Pharmacokinetics and Toxicity of Bismuth Compounds

Anja Slikkerveer1, de Wolff Fa2
1Toxicology Laboratory, University Hospital, P.O. Box 9600, 300, RA Leiden, The Netherlands
2Toxicology Laboratory, University Hospital, RA Leiden, The Netherlands

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Abbracchio MP, Balduini W, Cavallaro A, Adamoli P, Fittipaldi M, et al. Brain and blood levels of bismuth after oral or parenteral administration of tripotassium-dicitrato-bismuthate to rats. Neurotoxicology 6: 139–144, 1985

Allain P. Le dosage du bismuth dans les milieux biologiques par absorption atomique sans flamme. Clinica Chimica Acta 64: 281–286, 1975

Allain P, Alquier P, Dumont A-M. Étude expérimentale de l’élimination du bismuth par hémodialyse. Thérapie 31: 703–706, 1976

Allain P, Chaleil D, Emile J. L’élévation des concentrations de bismuth dans les tissues des malades intoxiqués. Thérapie 35: 303–304, 1980

Ayman D. Bismuth subnitrate in the treatment of arteriolar (essential) hypertension. Journal of the American Medical Association 98: 545–548, 1932

Bader JP. The safety profile of De-Nol®. Digestion 37 (Suppl. 2): 53–59, 1987

Badinand A, Quincy Cl. Étude expérimentale de la répartition du bismuth administré sous forme de chélate. Thérapie 14: 888–892, 1959

Basinger MA, Jones MM, McCroskey SA. Antidotes for acute bismuth intoxication. Journal of Toxicology — Clinical Toxicology 20: 159–165, 1983

Beaver DL, Burr RE. Bismuth inclusions in the human kidney. Archives of Pathology 76: 89–94, 1963a

Beaver DL, Burr RE. Electron microscopy of bismuth inclusions. American Journal of Pathology 42: 609–613, 1963b

Beerman H. Fatalities due to bismuth in the treatment of syphilis. Archives of Dermatology and Syphilogy 26: 797–801, 1932

Bertholf RL, Renoe BW. The determination of bismuth in serum and urine by electrothermal atomic absorption spectrometry. Analytica Chimica Acta 139: 287–295, 1982

Bès A, Caussanel JP, Géraud G, Jauzac Ph, Géraud J. Encéphalopathie toxique par les sels de bismuth. Revue de Médecine de Toulouse 12: 801–813, 1976

Billiard M, Besset A, Renaud B, Baldy-Moulinier M, Passouant P. L’insomnie de l’encéphalopathie bismuthique. Revue d’Electroencéphalographie et de Neurophysiologie Clinique 7: 147–152, 1977

Billon JP, Gernez G, Gourdin JC, Martin Ch, Pallière M. Quelques caractéristiques physicochimiques de sels de bismuth utilisés en pharmacie. Annales Pharmaceutiques Françaises 34: 161–171, 1976

Boiteau H-L, Cler J-M, Mathé J-F, Delobel R, Fève J-R. Relations entre l’évolution des encéphalopathies bismuthiques et les taux de bismuth dans le sang et dans les urines. European Journal of Toxicology 9: 233–239, 1976

Boudène C, Bouley G, Belegaud J, Comoy E. Recherches étiologiques et pathogéniques expérimentales sur la toxicité du sousnitrate de bismuth lourd micronisé chez le rat. Journal de Pharmacologie 10: 93–104, 1979

Bourdon R, Galliot M, Prouillet F. Dosage du cuivre, du plomb, du manganèse, du bismuth, du cadmium et de l’or dans les liquides biologiques par spectrométrie d’absorption atomique sans flamme. Annales de Biologie Clinique 32: 413–422, 1974

Boyette DP, Ahoskie AC. Bismuth nephrosis with anuria in an infant: report of a case. Journal of Pediatrics 28: 493–497, 1946

Bruen C. The therapeutic efficacy of bismuth subnitrate in arterial hypertension. American Journal of the Medical Sciences 188: 21–32, 1934

Buge A, Hubault A, Rancurel G. Les arthropathies de l’intoxication par le bismuth. Revue du Rhumatisme et des Maladies Osteo-articulaires 42: 721–729, 1975

Buge A, Rancurel G, Dechy H. Encéphalopathies myocloniques bismuthiques formes évolutives, complications tardives, durables ou définitives. Revue Neurologique 133: 401–415, 1977

Buge A, Rancurel G, Dechy H. Encéphalopathies bismuthiques: données étiologiques et pharmacologiques. Nouvelle Presse Médicale 7: 3531–3534, 1978

Buge A, Rancurel G, Poisson M, Gazengel J, Dechy H, et al. 20 observations d’encéphalopathies aiguës avec myoclonies au cours de traitements oraux par les sels de bismuth. Annales de Médecine Interne 125: 877–888, 1974

Buge A, Supino-Viterbo V, Rancurel G, Metzger J, Dechy H, et al. Corrélations évolutives: cliniques électro-encéphalographiques, tomodensitométriques et toxicologiques, dans cinq cas d’encéphalopathies bismuthiques. Semaine des Hôpitaux de Paris 55: 1466–1472, 1979

Buge A, Supino-Viterbo V, Rancurel G, Pontes C. Epileptic phenomena in bismuth toxic encephalopathy. Journal of Neurology, Neurosurgery and Psychiatry 44: 62–67, 1981

Buijs WC, Corstens FH, Beentjes LB. Long-term retention of 207 Bi in the body after injection of 206 Bi. Health Physics 49: 1267–1269, 1985

Burns R, Thomas DW, Barron VJ. Reversible encephalopathy possibly associated with bismuth subgallate ingestion. British Medical Journal 1: 220–223, 1974

Burr RE, Gotto AM, Beaver DL. Isolation and analysis of renal bismuth inclusions. Toxicology and Applied Pharmacology 7: 588–591, 1965

Caruzzo F. L’encéphalopathie myoclonique bismuthique: une intoxication insolite. Revue de Médecine Thérapeutique 21: 1171–1177, 1980

Cervello MA, Alfaro A, Antolin MA, Penarrocha M. Encefalopatia mioclónica bismútica: a propósito de dos nuevas observaciones clínicas. Medicina Clinica 79: 137–140, 1982

Chaleil D, Allain P, Emile J. Étude de l’élimination urinaire et fécale du bismuth administré par voie parentérale. Pathologie Biologie 27: 417–420, 1979b

Chaleil D, Hugot P, Allain P. Augmentation des concentrations sanguines de bismuth par la cystéine chez le rat. Thérapie 34: 397–399, 1979a

Chaleil D, Lefevre F, Allain P, Martin GJ. Enhanced bismuth digestive absorption in rats by some sulfhydryl compounds: NMR study of complexes formed. Journal of Inorganic Biochemistry 15: 213–221, 1981

Chaleil D, Regnault JP, Allain P, Motta R, Raynaud G, et al. Action d’une flore microbienne méthanogène d’origine humaine sur l’absorption et la fixation du bismuth chez le rat. Annales Pharmaceutiques Françaises 46: 133–137, 1988

Cherian MG, Nordberg M. Cellular adaptation in metal toxicology and metallothionein. Toxicology 28: 1–15, 1983

Chou PP, Jaynes PK, Bailey JL. Determination of bismuth in urine by atomic absorption with hydride generation. Journal of Analytical Toxicology 8: 158–160, 1984

Coenegracht JM, Dorleyn M. The distribution of intravenously administered tracer doses of Bi206 compounds in the human body. Journal Belge de Radiologie 44: 485–504, 1961

Coffey GL, Graham JW. Mental illness or metal illness? Bismuth subgallate. Medical Journal of Australia 2: 885, 1974

Coghill SB, Hopwood D, McPherson S, Hislop S. The ultrastructural localisation of De-Nol® (colloidal tripotassium dicitratobismuthate-TDB) in the upper gastrointestinal tract of man and rodents following oral and instrumental administration. Journal of Pathology 139: 105–114, 1983

Collignon R, Bruyer R, Rectem D, Indekeu P, Laterre EC. Analyse sémiologique de l’encéphalopathie bismuthique. Acta Neurologica Belgica 79: 73–91, 1979

Conso F, Bourdon R, Gaultier M. Bismuth sanguin et urinaire après traitement bref par différents sels ‘insolubles’ de bismuth. European Journal of Toxicology 8: 137–141, 1975

Costa-Jussa Relat F, Aguilar Barbera M, Martinez Matos JA, Lopez Pousa S, Marti Vilalta JL. Encefalopatía por sales insolubles de bismuto: a propósito de tres observaciones clinicas. Revue Neurologique 7: 289–296, 1979

Cramer H, Renaud B, Billiard M, Mouret J, Hammers R. Monoaminmetabolite und zyklische Nukleotide des Liquor cerebrospinalis bei Wismut- und Quecksilber-Encephalopathien. Archiv für Psychiatrie und Nervenkrankheiten 226: 173–181, 1978

Czerwinski AW, Ginn HE. Bismuth nephrotoxicity. American Journal of Medicine 37: 969–975, 1964

De Bray J-M, Emile J, Moreau R, Daver A, Cheguillaume J, et al. Pathogénie des encéphalopathies bismuthiques: étude préliminaire à l’aide du bismuth206 chez l’homme. Nouvelle Presse Médicale 6: 1394, 1977

De Doncker K, Dumarey R, Dams R, Hoste J. The use of 1,10-phenanthroline in minimizing the nickel interference in determinations of bismuth and antimony by hydride generation/atomic absorption spectrometry. Analytica Chimica Acta 169: 339–341, 1985

Dekker W, Dal Monte PR, Bianchi Porro G, van Bentem N, Boekhorst JC, et al. An international multi-clinic study comparing the therapeutic efficacy of colloidal bismuth subcitrate coated tablets with chewing tablets in the treatment of duodenal ulceration. Scandinavian Journal of Gastroenterology 21 (Suppl. 122): 46–50, 1986

Dekker W, Reisma K. Double-blind controlled trial with colloidal bismuth subcitrate in the treatment of symptomatic duodenal ulcers, with special references to blood and urine bismuth levels. Annals of Clinical Research 11: 94–97, 1979

De Mol J, Loseke N, Leleux C. Troubles mentaux dans l’encéphalopathie bismuthique. Acta Psychiatrica Belgica 79: 185–197, 1979

Dérot M, Tanret P, Grivaut M. Erythrodermie vésiculo-oedémateuse d’origine bismuthique traitée avec succès par le 1–2 dimercaptopropanol. Bulletin et Memoires de la Societé de Médecine des Hôpitaux de Paris, 1090–1093, 1947

De Sèze S, Hioco D, Mazabraud A, Bordier Ph. Ostéoses décalcifiantes mixtes d’origine bismuthique: rapport de 7 cas. Revue du Rhumatisme et des Maladies Osteo-articulaires 25: 623–634, 1958

Djudzman R, Vanden Eeckhout E, De Moerloose P. Détermination du bismuth dans le sang et l’urine après traitement de courte durée avec des sels insolubles de bismuth. Acta Gastro-Enterologica Belgica 41: 81–86, 1978

D’Souza RW, Francis WR. Bioavailability and pharmacokinetics of bismuth in the rat. Abstract. Pharmaceutical Research 4 (Suppl.): S115, 1987

Dowds JH. Poisoning by sodium bismuth tartrate injections; three fatal cases. Lancet 2: 1039–1040, 1939

Emile J, De Bray JM, Bernat M, Morer T, Allain P. Les ostéopathies scapulaires et vertébrales des encéphalopathies aiguës myocloniques bismuthiques. Annales de Médecine Interne 130: 75–80, 1979

Emile J, De Bray JM, Bernat M, Morer T, Allain P. Osteoarticular complications in bismuth encephalopathy. Clinical Toxicology 18: 1285–1290, 1981

Emile J, Feve J, Bastard J, Clerc P, de Bray J, et al. Encéphalopathie aiguë myoclonique résolutive: rôle probable de l’ingestion d’un sel de bismuth. Archives Médicales de l’Ouest 6: 699–722, 1974

Erdani S, Balzarini M, Taglioretti D, Romussi M, Valentini R. The distribution of radiobismuth in the rat. British Journal of Radiology 37: 311–314, 1964

Escourolle R, Bourdon R, Galli A, Galle P, Jaudon MC, et al. Étude neuropathologique et toxicologique de douze cas d’encéphalopathie bismuthique. Revue Neurologique 133: 153–163, 1977

Ferrer X, Raymond JM, Begaud B, Raptopoulo F, Lagueny A, et al. Encéphalopathie bismuthique. Persistance du risque avec les préparations magistrales. Presse Médicale 13: 1749–1750, 1984

Fowler BA, Goyer RA. Bismuth localization within nuclear inclusions by x-ray microanalysis. Journal of Histochemistry and Cytochemistry 23: 722–726, 1975

Fowler BA, Vouk V. Bismuth. In Friberg et al. (Eds) Handbook on the toxicology of metals, 2nd ed., Vol. II, pp. 117–129, Elsevier, Amsterdam, 1986

Froomes PRA, Wan AT, Harrison PM, McLean AJ. Improved assay for bismuth in biological samples by atomic absorption spectrophotometry with hydride generation. Clinical Chemistry 34: 382–384, 1988

Ganrot PO. Metabolism and possible health effects of aluminum. Environmental Health Perspectives 65: 363–441, 1986

Garcia JL, Penin F, Weber M, Regent MCh, Cuny G. Les lésions ostéo-articulaire au cours des encéphalopathies aiguës bismuthiques. Revue du Rhumatisme et des Maladies Osteo-articulaires 47: 275–280, 1980

Gardeur D, Buge A, Rancurel G, Dechy H, Metzger J. Bismuth encephalopathy and cerebral computed tomography. Journal of Computer Assisted Tomography 2: 436–438, 1978

Gastaut JL, Tassarini CA, Terzano G, Picornell I. Étude polygraphique de l’encéphalopathie myoclonique bismuthique. Revue d’Electroencéphalographie et de Neurophysiologie Clinique 5: 295–302, 1975

Gaucher A, Netter P, Faure G, Hutin MF. Le dosage du bismuth dans l’os: son intérêt clinique. Thérapie 35: 297–299, 1980a

Gaucher A, Netter P, Faure G, Pourel J, Hutin MF, et al. Les ostéoarthropathies ‘bismuthiques’: intérêt du dosage du bismuth osseux. Revue du Rhumatisme et des Maladies Osteoarticulaires 47: 31–35, 1980b

Gavey CJ, Szeto M-L, Nwokolo CU, Sercombe J, Pounder RE. Bismuth accumulates in the body during treatment with tripotassium dicitrato bismuthate. Alimentary Pharmacology and Therapeutics 3: 21–28, 1989

Ghadially FN. Ultrastructural localization and in situ analysis of iron, bismuth and gold inclusions. CRC Critical Reviews in Toxicology 6: 303–350, 1979

Goas JY, Borsotti JP, Missoum A, Allain P, Chaleil D. Encéphalopathie myoclonique par le sous-nitrate de bismuth. Nouvelle Presse Médicale 10: 3855, 1981

Goodman L. Sudden death after intravenous sodium bismuth tartrate. British Medical Journal 1: 978–979, 1948

Goule JP, Husson A, Fondimare A, Rapoport F, Lebreton M, et al. Encéphalopathie aux sels insolubles de bismuth. Nouvelle Presse Médicale 4: 1366, 1975

Goyer RA. Toxic effects of metals. Bismuth. In Klaassen et al. (Eds) Casarett and Doull’s toxicology, 3rd ed., p. 620, Macmillan Publishing Company, New York, 1986

Grandjean EM, Ducommun E, Gauthier G, Courvoisier B. L’encéphalopathie myoclonique associée aux sels de bismuth: recherche négative d’un élément toxique associé. Schweizerische Medizinische Wochenschrift 106: 1006–1011, 1976

Gregus Z, Klaassen CD. Disposition of metals in rats: a comparative study of fecal, urinary and biliary excretion and tissue distribution of eighteen metals. Toxicology and Applied Pharmacology 85: 24–38, 1986

Gryboski JD, Gotoff SP. Bismuth nephrotoxicity: report of a case. New England Journal of Medicine 265: 1289–1291, 1961

Guard O, Soichot P, Dumas R, Besancenot J-B, Gaudet M. Réflexions a propos de dix observations d’encéphalopathie bismuthique. Journal de Médecine de Lyon 58: 403–416, 1977

Guilbert F, De Bray JM, Girault M. Chromatographie des acides aminés urinaires au cours d’encéphalopathie bismuthique. Pathologie Biologie 26: 572–576, 1978

Hall RJ, Farber T. Drug residues in animal tissues: determination of bismuth in body tissues and fluids after administration of controlled doses. Journal of the Association of Official Analytical Chemists 55: 639–642, 1972

Hamilton EI, Minski MJ, Cleary JJ. The concentration and distribution of some stable elements in healthy human tissues from the United Kingdom. Science of the Total Environment 1: 341–374, 1972/73

Hartemann P, Maugras M. Intoxications bismuthiques: un suspect, l’acide lactique. Nouvelle Presse Médicale 5: 1001, 1976

Hasking GJ, Duggan JM. Encephalopathy from bismuth subsalicylate. Medical Journal of Australia 2: 167, 1982

Hazemann P, Rebelo F, Landau J. Encéphalopathie par le bismuth. Revue d’Electroencéphalographie et de Neurophysiologie Clinique 5: 291–294, 1975

Heller RH, Waitsmann ES. Bismuth ingestion simulating acute plumbism on abdominal roentgenogram. Journal of Pediatrics 76: 637–638, 1970

Hespe W, Staal HJM, Hall DWR. Bismuth absorption from the colloidal subcitrate. Lancet 2: 1258, 1988

Hillemand P, Cottet J. A propos de la toxicité du sous-nitrate de bismuth et des règles de son emploi en thérapeutique digestive. Bulletin de l’Académie Nationale de Médecine 160: 274–278, 1976

Hillemand P, Pallière M, Laquais B, Bouvet P. Traitement bismuthique et bismuthémie. Semaine des Hôpitaux de Paris 53: 1663–1669, 1977

Hudson M, Mowat NAG. Colloidal bismuth subcitrate (De-Nol®) self-poisoning — reversible toxicity. British Medical Journal, in press, 1989

Hursh JB, Brown C. Tissue distribution of 212 Bi in rats. Proceedings of the Society for Experimental Biology and Medicine 131: 116–120, 1969

Ibels LS, Pollock CA. Lead intoxication. Medical Toxicology 1: 387–410, 1986

Indekeu P, Laterre Ch. L’encéphalopathie bismuthique a propos de 5 observations. Acta Clinica Belgica 33: 350–362, 1978

Irth H, Brouwer E, de Jong GJ, Brinkman UATh, Frei RW. Trace enrichment and separation of AsIII, SbIII as diethyldithiophosphate complexes by reversed-phase high-performance liquid chromatography. Journal of Chromatography 439: 63–70, 1988

James JJ. Acute renal failure due to a bismuth preparation. California Medicine 109: 317–319, 1968

Jeanrot R, Chaleil D, Allain P, Papillon C, Raynaud G, et al. Fixation sur les tissus du bismuth administré par voie orale chez le rat: influence de la flore microbienne digestive. Toxicological European Research 4: 181–185, 1982

Karelitz S, Freedman AD. Hepatitis and nephrosis due to soluble bismuth. Pediatrics 8: 772–777, 1951

Komsta-Szumska E, Chmielnicka J, Piotrowski JK. The influence of selenium on binding of inorganic mercury by metallothionein in the kidney and liver of the rat. Biochemical Pharmacology 25: 2539–2540, 1976

Krüger G, Thomas DJ, Weinhardt F, Hoyer S. Disturbed oxidative metabolism in organic brain syndrome caused by bismuth in skin creams. Lancet 2: 485–487, 1976

Kulchar GV, Reynolds WJ. Bismuth hepatitis. A survey of 121 cases. Journal of the American Medical Association 120: 343–348, 1942

Lagier G. Encéphalopathies bismuthiques: situation dans les pays autres que la France. Thérapie 35: 315–317, 1980

Lagueny A, Vallat J-M, Julien J. Enregistrement électromyographique au cours des encéphalopathies par les sels de bismuth. Nouvelle Presse Médicale 5: 2252–2253, 1976

Lazarini F. On the hydrolysis of bisuth (III) nitrate — the predominant role of the Bi6 O4 (OH)4 6+ cation. Bulletin of the Bismuth Institute 32: 3–8, 1981

Lechat P, Kisch R. Les encéphalopathies bismuthiques: réévaluation du risque. Gastroenterologie Clinique et Biologique 10: 562–569, 1986

Lechat P, Majoie B, Levillain R, Cluzan R, Deleau D. Étude de la toxicité à court terme de l’association sous-nitrate de bismuth et sorbitol. Thérapie 19: 551–556, 1964

Lechat P, Pallière M, Gernez G, Dechy H, Letteron N. Répartition comparée du bismuth dans l’organisme du rat après administration orale répétée de différent sels. Annales Pharmaceutiques Françaises 34: 179–182, 1976

Lee SP. Studies on the absorption and excretion of tripotassiumdicitrato-bismuthate in man. Research Communications in Chemical Pathology and Pharmacology 43: 359–364, 1981

Lee SP, Lim TH, Pybus J, Clarke AC. Tissue distribution of orally administered bismuth in the rat. Clinical and Experimental Pharmacology and Physiology 7: 319–324, 1980

Lhermitte F, Mallecourt J, Chedru F, Kuperwasser B, Glaser P. Encéphalopathie aiguë mortelle avec ostéonécrose des deux têtes humérales après ingestion de doses minimes de sels insolubles de bismuth. Nouvelle Presse Médicale 7: 2170–2171, 1978

Liessens JL, Monstrey J, Vanden Eeckhout E, Djudzman R, Martin JJ. Bismuth encephalopathy: a clinical and anatomo-pathological report of one case. Acta Neurologica Belgica 78: 301–309, 1978

Loiseau P, Henry P, Jallon P, Legroux M. Encéphalopathies myocloniques iatrogènes aux sels de bismuth. Journal of the Neurological Sciences 27: 133–143, 1976

Loseke N, Retif J, Coune A, Soebert A, Molle L, et al. L’encéphalopathie myoclonique bismuthique. Acta Gastro-Enterologica Belgica 41: 72–80, 1978

Lotstra F, Soebert A, Linkowski P, Mendlewicz J. A propos du dix-huitième cas connu d’encéphalopathie au bismuth en Belgique. Acta Neurologica Belgica 83: 135–141, 1983

Lowe DJ. Adverse effects of bismuth subgallate: a further report from the Australian Drug Evaluation Committee. Medical Journal of Australia 2: 664–666, 1974

Mabille JP, Gaudet M, Charpin JF. Ostéonécrose de la tête numérale au cours de l’encéphalopathie bismuthique. Annales de Radiologie 23: 515–517, 1980

Mabin D, Goas J-Y, Bedou G, Besson G, Tuset M-C. Aspects cliniques et électroencéphalographiques de l’encéphalopathie par les sels insolubles de bismuth. Semaine des Hôpitaux de Paris Thérapeutique 52: 109–116, 1976

Marshall BJ, Armstrong JA, Francis GJ, Nokes NT, Wee SH. Antibacterial action of bismuth in relation to Campylobacter pyloridis colonization and gastritis. Digestion 37 (Suppl. 2): 16–30, 1987

Martin-Bouyer G. Intoxications par les sels de bismuth administrés par voie orale: enquête épidémiologique. Thérapie 31: 683–702, 1976

Martin-Bouyer G, Barin C, Beugnet A, Cordier J, Guerbois H. Intoxications par les sels de bismuth administrés par voie orale. Gastroenterologie Clinique et Biologique 2: 349–356, 1978

Martin-Bouyer G, Foulon B, Guerbois H, Barin C. Aspects épidémiologiques des encéphalopathies après administration de bismuth par voie orale. Thérapie 35: 307–313, 1980

Martin-Bouyer G, Foulon G, Guerbois H, Barin C. Epidemiological study of encephalopathies following bismuth administration per os: characteristics of intoxicated subjects — comparison with a control group. Clinical Toxicology 18: 1277–1283, 1981a

Martin-Bouyer G, Nevot P, Singlas E,, Foulon G, Philippon A, et al. Rôle possible de la flore intestinale dans les intoxications par le bismuth. Thérapie 36: 483–488, 1981b

Matsusaki K, Yoshino T, Yamamoto Y. Interference effect of chloride on the determination of bismuth by electrothermal atomic absorption spectrometry. Analytica Chimica Acta 167: 299–304, 1985

Mattle H, Henn V, Baumgartner G. Akutes Delir bei Wismut-Intoxikation. Schweizerische Medizinische Wochenschrift 112: 1308–1311, 1982

McClendon SJ. Toxic effects with anuria from a single injection of a bismuth preparation: report of two cases. American Journal of Diseases of Children 61: 339–341, 1941

McLean AJ, Froomes P, McNeil JJ, Wan AT, Harrison PM. Bismuth subcitrate handling in man. Abstract. Clinical Pharmacology and Therapeutics 43: 186, 1988

Mehrtens HG, Hanzlik PJ, Marshall DC, Brown NS. Bismuth as a diuretic. Journal of the American Medical Association 91: 223–225, 1928

Metzger J, Buge A, Rancurel G, Gardeur D. Aspects tomodensitométriques de trois observations d’encéphalopathies bismuthiques aiguës. Revue Neurologique 134: 619–624, 1978

Moindrot J, Evreux JC, Savet JF, Aimard G. Encéphalopathies bismuthiques: bilan et commentaires. Lyon Médical 238: 537–541, 1977

Molina JA, Calandre L, Bermejo F. Myoclonic encephalopathy due to bismuth salts: treatment with dimercaprol and analysis of CSF transmitters. Acta Neurologica Scandinavica 79: 200–203, 1989

Monseu G, Struelens M, Roland M. Bismuth encephalopathy. Acta Neurologica Belgica 76: 301–308, 1976

Müller H-A, von Ramin D. Morphologie und Morphogenese der durch Schwermetalle (Pb, Bi) hervorgerufenen Kerneinschlüsse in den Hauptstückepithelien der Rattenniere. Beitragen zur Pathologischen Anatomie und Allgemeinen Pathologie 128: 445–467, 1963

Murray JR. Bismuth neurotoxicity. Medical Journal of Australia 1: 279–280, 1978

Murray JR. Bismuth-induced osteoarthropathies. Medical Journal of Australia 1: 522, 1979

Nogué S, Mas A, Parés A, Nadal P, Bertrán A, et al. Encefalopatía mioclónica y convulsiva por bismuto: utilidad del tratamiento con dimercaprol. Medicina Clinica 84: 530–532, 1985

Nwokolo CU, Gavey CJ, Smith JTL, Pounder RE. The absorption of bismuth from oral doses of tripotassium dicitrato bismuthate. Alimentary Pharmacology and Therapeutics 3: 29–39, 1989

O’Brien D. Anuria due to bismuth thioglycollate. American Journal of Diseases of Children 97: 384–386, 1959

Olive G. Recherches menées par 1TNSERM sur les encéphalopathies myocloniques provoquées par les sels insolubles de bismuth utilisés en gastro-entérologie. Thérapie 35: 305–306, 1980

Pallière P, Gernez G. Technique de dosage par spectrométrie d’absorption atomique du bismuth dans les milieux biologiques. Annales Pharmaceutiques Françaises 34: 183–188, 1976

Passouant P, Billiard M, Besset A, Renaud B. Encephalopathy associated with bismuth salt ingestion and brain monoamines. International Journal of Neurology 12: 199–204, 1979

Pellerin F, Goullé J-P, Dumitrescu D. La formation de complexes et chélates solubles de bismuth avec divers médicaments et aliments; detection par absorption atomique. Annales Pharmaceutiques Françaises 35: 281–286, 1977

Pellerin F, Mancheron D. La formation de chélate nitrate de bismuth sorbitol, son incidence dans les préparations pharmaceutiques. Annales Pharmaceutiques Françaises 25: 797–802, 1967

Pieri F, Wegmann R. Étude pharmacocinétique du 206 Bi-citrate chez le rat: répartition compartimentale. Cellular and Molecular Biology 27: 57–60, 1981

Piotrowski JK, Szymanska JA. Influence of certain metals on the level of metallothionein-like proteins in the liver and kidneys of rats. Journal of Toxicology and Environmental Health 1: 991–1002, 1976

Piotrowski JK, Szymanska JA, Mogilnicka EM, Zelazowski AJ. Renal metal binding proteins. Experientia Supplement 34: 363–371, 1979

Randall RE, Osherhoff RJ, Bakerman S, Setter JG. Bismuth nephrotoxicity. Annals of Internal Medicine 77: 481–482, 1972

Rauws EAJ, Langenberg W, Houthoff HJ, Zamen HC, Tytgat GNJ. Campylobacter pyloridis-associated chronic active antral gastritis: a prospective study of its prevalence and the effects of antibacterial and antiulcer treatment. Gastroenterology 94: 33–40, 1988

Ravault P, Lejeune E, Pellet M. Les ostéoses décalcifiantes d’origine bismuthique (étude critique a propos de 14 observations chez l’adulte). Revue Lyonnaise de Médecine 7: 827–837, 1958

Reinicke C. Bismuth. In Dukes (Ed.) Dukes side effects of drugs (Annual 6), pp. 217–221, Excerpta Medica, Amsterdam, 1982

Ribadeau-Dumas J-L, Lechevalier B, Breteau M, Allain Y. Encéphalopathie bismuthique: répartition intra-cérébrale du bismuth. Nouvelle Presse Médicale 7: 4021–4025, 1978

Robertson JF. Mental illness or metal illness? Bismuth subgallate. Medical Journal of Australia 1: 887–888, 1974

Rooney RC. Determination of bismuth in blood and urine. Analyst 101: 749–752, 1976

Russ GA, Bigler RE, Tilbury RS, Woodard HQ, Laughlin JS. Metabolic studies with radiobismuth, I: retention and distribution of 206 Bi in the normal rat. Radiation Research 63: 443–454, 1975

Sany J, Bataille R, Rosenberg F, Ántoine L, Serre H, et al. Arthropathie de l’épaule par intoxication au bismuth. Revue du Rhumatisme et des Maladies Osteo-articulaires 45: 729–732, 1978

Serfontein WJ, Mekel R. Bismuth toxicity in man II: review of bismuth blood and urine levels in patients after administration of therapeutic bismuth formulations in relation to the problem of bismuth toxicity in man. Research Communications in Chemical Pathology and Pharmacology 26: 391–411, 1979

Sollmann T, Cole HN, Henderson K. Clinical excretion of bismuth, VII: the autopsy distribution of bismuth in patients after clinical bismuth treatment. American Journal of Syphilis, Gonorrhea and Venereal Diseases 22: 555–583, 1938

Sollman T, Seifter J. The pharmacology of trimethyl bismuth. Journal of Pharmacology and Experimental Therapeutics 67: 17–49, 1939

Sollmann T, Seifter J. Intravenous injections of soluble bismuth compounds: their toxicity and their sojourn in the blood and organs. Journal of Pharmacology and Experimental Therapeutics 74: 134–154, 1942

Soutar RL, Coghill SB. Interaction of tripotassium dicitrato bismuthate with macrophages in the rat and in vitro. Gastroenterology 91: 84–93, 1986

Stahl JP, Gaillat J, Leverve X, Carpentier F, Guignier M, et al. Encéphalites au sel insoluble de bismuth: toujours d’actualité. Nouvelle Presse Médicale 11: 3856, 1982

Stieglitz EJ. Bismuth subnitrate in the treatment of arterial hypertension. Journal of the American Medical Association 95: 842–846, 1930

Stiel D, Murray DJ, Peters TJ. Uptake and subcellular localisation of bismuth in the gastrointestinal mucosa of rats after short term administration of colloidal bismuth subcitrate. Gut 26: 364–368, 1985

Supino-Viterbo V, Sicard C, Cathala H-P. Altérations E.E.G. observées chez 15 malades atteints d’encéphalopathie par les sels de bismuth. Revue d’Electroencéphalographie et de Neurophysiologie Clinique 7: 139–146, 1977a

Supino-Viterbo V, Sicard C, Risvegliato M, Rancurel G, Buge A. Toxic encephalopathy due to ingestion of bismuth salts: clinical and EEG studies of 45 patients. Journal of Neurology, Neurosurgery and Psychiatry 40: 748–752, 1977b

Szymańska JA, Mogilnicka EM, Kaszper BW, Binding of bismuth in the kidneys of the rat: the role of metallothionein-like proteins. Biochemical Pharmacology 26: 257–258, 1977

Szymańska JA, Piotrowski JK. Studies to identify the low molecular weight bismuth-binding proteins in rat kidney. Biochemical Pharmacology 29: 2913–2918, 1980

Szymańska JA, Zelazowski AJ. Induced synthesis of chromochelatin, the low molecular weight bismuth-binding protein in rat kidneys. Chemico-Biological Interactions 26: 139–146, 1979a

Szymańska JA, Zelazowski AJ. Effect of cadmium, mercury and bismuth on the copper content in the rat tissues. Environmental Research 19: 121–126, 1979b

Szymańska JA, Zelazowski AJ, Kawiorski S. Some aspects of bismuth metabolism. Clinical Toxicology 18: 1291–1298, 1981

Szymańska JA, Zychowicz M, Zelazowski AJ, Piotrowski JK. Effect of selenium on the organ distribution and binding of bismuth in rat tissues. Archives of Toxicology 40: 131–141, 1978

Thomas DW, Hartley TF, Coyle P, Sobecki S. Clinical and laboratory investigations of the metabolism of bismuth containing pharmaceuticals by man and dogs. In Brown (Ed.) Clinical chemistry and chemical toxicology of metals, pp. 293–296, Elsevier/North Holland Biomedical Press, Amsterdam, 1977

Thomas DW, Sobecki S, Hartley TF, Coyle P, Alp MH. Variable absorption and excretion of bismuth and its potential for tox icity. In Brown & Savory (Eds) Chemical toxicology and clinical chemistry of metals, pp. 391–394, Academic Press, London, 1983

Urizar R, Vernier RL. Bismuth nephropathy. Journal of the American Medical Association 198: 207–209, 1966

Van der Werff JTh. Radioactive bismuth 206 Bi. Experimental studies and clinical applications. Acta Radiologica (Suppl. 243): 3–49, 1965

Vidailhet M, Le Thi Huong Du, Wechsler B, Godeau P, L’encéphalopathie au bismuth n’a pas disparu. Presse Médicale 16: 1054, 1987

Vienet R, Bouvet P, Istin M. Cinétique et distribution du 206 Bi chez le rat et le lapin: un modèle. International Journal of Applied Radiation and Isotopes 34: 747–753, 1983

Wagstaff AJ, Benfield P, Monk JP. Colloidal bismuth subcitrate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in peptic ulcer disease. Drugs 36: 132–157, 1988

Warren HV, Horsky SJ, Gould CE. Quantitative analysis of zinc, copper, lead, molybdenum, bismuth, mercury and arsenic in brain and other tissues from multiple sclerosis and non-multiple sclerosis cases. Science of the Total Environment 29: 163–169, 1983

Weller MPI. Neuropsychiatric symptoms following bismuth intoxication. Postgraduate Medical Journal 64: 308–310, 1988

Wieriks J, Hespe W, Jaitly KD, Koekkoek PH, Lavy U. Pharmacological properties of colloidal bismuth subcitrate (CBS, De-Nol®). Scandinavian Journal of Gastroenterology 17 (Suppl. 80): 11–16, 1982

Williams DR. Analytical and computer simulation studies of a colloidal bismuth citrate system used as an ulcer treatment. Journal of Inorganic and Nuclear Chemistry 39: 711–714, 1977

Winge DR, Premakumar R, Rajagopalan KV, Metal-induced formation of metallothionein in rat liver. Archives of Biochemistry and Biophysics 170: 242–252, 1975

Winship KA. Toxicity of bismuth salts. Adverse Drug Reactions and Acute Poisoning Reviews 2: 103–121, 1983

Woods JS, Fowler BA. Alteration of mitochondrial structure and heme biosynthetic parameters in liver and kidney cells by bismuth. Toxicology and Applied Pharmacology 90: 274–283, 1987

Woolrich PF. Occurrence of trace metals in the environment: an overview. American Industrial Hygiene Association Journal 217–226, 1973

Zarranz JJ, Forcadas I, Larracoechea J, Caldera A. Encefalopatía mioclónica debida a intoxicación por sales insolubles de bismuto. Medicina Clinica 68: 78–80, 1977

Zelazowski AJ, Piotrowski JK. Mercury-binding, copper-zinc proteins from rat kidney: amino acid composition, molecular weight and metal content. Biochimica et Biophysica Acta 625: 89–99, 1980

Zidenberg-Cherr S, Parks NJ, Keen CL. Tissue and subcellular distribution of bismuth radiotracer in the rat: considerations of cytotoxicity and microdosimetry for bismuth radiopharmaceuticals. Radiation Research 111: 119–129, 1987