Pharmaceutical supply chains: key issues and strategies for optimisation

Computers and Chemical Engineering - Tập 28 Số 6-7 - Trang 929-941 - 2004
Nilay Shah1
1Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College of Science, Technology and Medicine, London SW7 2BY, UK

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Anon (2002). Summary of the executive session on emergency preparedness and the pharmaceutical supply chain. American Journal of Health-System Pharmacy, 59 (3), 247–253.

Applequist, 2000, Risk and uncertainty in managing chemical manufacturing supply chains, Computers of Chemical Engineering, 24, 2211, 10.1016/S0098-1354(00)00585-8

Ballance, R., Pogany, J. & Forstner, H. (1992). The world’s pharmaceutical industries. London, UK: Edward Elgar [for UNIDO].

Barbosa-Povoa, 1999, Design of multipurpose production facilities: A RTN decomposition-based algorithm, Computers of Chemical Engineering, 23, S7, 10.1016/S0098-1354(99)80003-9

Bhagwat, 1995, Analysis of riskiness of pharmaceutical industry firms, Journal of Research in Pharmaceutical Economics, 6, 65, 10.1300/J063v06n01_05

Blau, 2000, Risk management in the development of new products in highly regulated industries, Computers of Chemical Engineering, 24, 1005, 10.1016/S0098-1354(00)00388-4

Booth, R. (1999). The global supply chain. FT healthcare management report. London: Financial Times Business Ltd.

Butler, 2002, The end of the blockbuster, Chemistry & Industry, 9, 9

Clay, 1997, A disaggregation algorithm for the optimization of stochastic planning models, Computers of Chemical Engineering, 21, 751, 10.1016/S0098-1354(96)00286-4

Eli Lilly (2003). http://www.newsroom.lilly.com/news/Financial/2003-01-23_q402sales_fullyear_2002.html.

Eppen, 1987, A scenario approach to capacity planning, Optical Research, 37, 517, 10.1287/opre.37.4.517

Gatica, G., Shah, N., & Papageorgiou, L. G. (2001). Capacity planning under clinical trials uncertainty for the pharmaceutical industries. In Proceedings of the ESCAPE-11 (pp. 865–870) Kondig, Denmark.

Gatica, G., Papageorgiou, L. G., & Shah, N. (2002a). Capacity planning under uncertainty for the pharmaceutical industry. Transformation of Institute of Chemical Engineering: Part A.

Gatica, G., Papageorgiou, L. G., & Shah, N. (2002b). An aggregation approach for capacity planning under uncertainty for the pharmaceutical industry. FOCAPO-2003.

Gjerdrum, J., Jalisi, Q. W. Z., Papageorgiou, L. G., & Shah, N. (2000). Dynamic simulation of physical and business processes for supply chain improvement. In Proceedings of the 5th Annual Conference on Industrial Engineering Theory, Applications and Practice. Hsinchu, Taiwan.

Gjerdrum, 2001, New product introduction supply chain planning. In O.-P. Hilmola, editor, Contemporary Research Issues in New Product Introduction. Acta Wasaensia, 77, 25

Grabowski, 1997, The effect of pharmacoeconomics on company research and development decisions, Pharmacoeconomics, 11, 389, 10.2165/00019053-199711050-00002

Henning, 1994, Design and planning of multipurpose plants involving nonlinear processing networks, Computers of Chemical Engineering, 18, 129, 10.1016/0098-1354(94)80133-9

Jain, 1999, Resource-constrained scheduling of tests in new product development, Industrial Engineering and Chemical Research, 38, 3013, 10.1021/ie9807809

Kall, P., & Wallace, S. W. (1994). Stochastic programming. New York: Wiley.

Lazaro, 1989, A comprehensive approach to production planning in multipurpose batch plants, Computers of Chemical Engineering, 13, 1031, 10.1016/0098-1354(89)87045-0

Lerwent, J. (1994). The new pharmaceutical paradigm: scientific management at Merck. Harvard Business Review, Jan-Feb, 88–89.

Linninger, 1996, Knowledge-based validation and waste management of batch pharmaceutical process designs, Computers of Chemical Engineering, 20, S1431, 10.1016/0098-1354(96)00245-1

Maravelias, 2001, Simultaneous planning for new product development and batch manufacturing facilities, Industrial Engineering of Chemical Research, 40, 6147, 10.1021/ie010301x

Mauderli, 1979, Production planning and scheduling for multipurpose batch chemical plants, Computers of Chemical Engineering, 3, 199, 10.1016/0098-1354(79)80033-2

Mauderli, 1980, Scheduling production in multipurpose batch plants: the Batchman program, Chemical Engineering Progress, 4, 37

Moser, 2000, Cleaning validation of a multipurpose plant for active pharmaceutical ingredient bulk production, Chimia, 54, 731, 10.2533/chimia.2000.731

Mulvey, 1997, Strategic financial risk management and operations research, EJOR, 97, 1, 10.1016/S0377-2217(96)00222-6

Myers, S. (1999). Measuring pharmaceutical risk and the cost of capital. In J. Sussex, & N. Marchant, editors. Risk and return in the pharmaceutical industry (pp. 59–76). London: OHE.

Papageorgaki, 1990, Optimal design of multipurpose batch plants, Industrial Engineering of Chemical Research, 29, 2054, 10.1021/ie00106a013

Papageorgiou, 1996, Optimal campaign planning/scheduling of multipurpose batch/semicontinuous tasks. 1. Mathematical formulation, Industrial Engineering of Chemical Research, 35, 488, 10.1021/ie950081l

Papageorgiou, G. E., Rotstein, G.E. & Shah, N. (2001). Strategic supply chain optimization for the pharmaceutical industries. Industrial Engineering of Chemical Research 40, 275–286.

Reklaitis, G. V. (1991). Perspectives on scheudling and planning of process operations. In Proceedings of the PSE-1991. Montebello, Canada.

Rotstein, 1999, A product portfolio approach in the pharmaceutical industry, Computers of Chemical Engineering, 23, 883, 10.1016/S0098-1354(99)80217-8

Schmidt, 1996, Optimization models for the scheduling of testing tasks in new product development, Industrial Engineering of Chemical Research, 35, 3498, 10.1021/ie9601099

Shah, 1998, Single- and multisite planning and scheduling: current status and future challenges, AIChE Symposium Series, 320, 75

Shah, 1991, Optimal long-term campaign planning and design of batch plants, Industrial Engineering of Chemical Research, 30, 2308, 10.1021/ie00058a010

Shah, 1992, Design of multipurpose batch plants with uncertain production requirements, Industrial Engineering of Chemical Research, 31, 1325, 10.1021/ie00005a013

Shah, 2000, Modelling and optimisation for pharmaceutical and fine chemical process development, AIChE Symposium Series, 323, 31

Sparrow, 1975, The choice of equipment sizes for multiproduct batch plants: heuristics versus branch-and-bound, Industrial Engineering and Process Design Development, 14, 197, 10.1021/i260055a001

Stephanopoulos, 2000, Batch process development: challenging traditional approaches, AIChE Symposium Series, 323, 46

Subramanian, 2001, A simulation-optimization framework for Research and Development Pipeline management, AIChE Journal, 47, 2226, 10.1002/aic.690471010

Thwaites, 1998, Pharmacoeconomics in the new millenium, Pharmacoeconomics, 13, 175, 10.2165/00019053-199813020-00002

van der Vorst, 2000, Modelling and simulating multi-echelon food systems, EJOR, 122, 354, 10.1016/S0377-2217(99)00238-6

Voudouris, 1992, Mixed-integer linear-programming reformulations for batch process design with discrete equipment sizes, Industrial Engineering of Chemical Research, 31, 1315, 10.1021/ie00005a012

Yeh, 1987, Synthesis and sizing of batch/semicontinuous processes: single product plants, Computers of Chemical Engineering, 11, 639, 10.1016/0098-1354(87)87009-6