Phacoemulsification versus manual small‐incision cataract surgery for age‐related cataract: meta‐analysis of randomized controlled trials

Clinical and Experimental Ophthalmology - Tập 41 Số 4 - Trang 379-386 - 2013
Jiayu Zhang1, Yifan Feng2, Jianqiu Cai3
1The Third Affiliated Hospital, Ruian People's Hospital of Wenzhou Medical College, Zhejiang, China
2The Affiliated Eye Hospital of Wenzhou Medical College, Zhejiang, China
3The Second Affiliated Hospital, Yuying Children's Hospital of Wenzhou Medical College, Zhejiang, China

Tóm tắt

AbstractBackgroundTo compare outcomes of phacoemulsification (PE) with manual small‐incision cataract surgery (MSICS) for age‐related cataract.DesignMeta‐analysis.ParticipantsPatients from previously reported randomized controlled trials (RCTs) of PE and MSICS with clinical outcomes.MethodsA comprehensive literature search of Cochrane Library, PubMed and EMBASE to identify relevant RCTs comparing PE and MSICS. A meta‐analysis was performed on the results and a RevMan 5.0 software (version 5.0; Cochrane Collaboration, Oxford, UK) was used for data analysis.Main Outcome MeasuresPrimary outcome measures included best corrected vision acuity (BCVA), uncorrected visual acuity (UCVA). Secondary outcome measures included surgically induced astigmatism (SIA), percentage of endothelial cell count (ECC) loss and complications.ResultsSix RCTs describing a total of 1315 eyes were identified. There were no significant differences between the techniques regarding the BCVA 6/9 or better (P = 0.69) and less than 6/18 (P = 0.68), percent of ECC loss (P = 0.45), intraoperative or postoperative complications (P = 0.44 and P = 0.87, respectively). However, a greater proportion of patients in the PE group had final UCVA ≥ 6/9 (P = 0.03), whereas a greater proportion of patients in the MSICS group had final UCVA < 6/18 (P = 0.03). Moreover, PE group induced less SIA (P < 0.00001).ConclusionsPE is superior to MSICS in UCVA and causes less SIA, but there were no significant differences in visual rehabilitation, ECC loss and complication rates between the two techniques.

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Clinical and Experimental Ophthalmology

Tập 41 Số 4

379-386

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