Perivascular niches: critical hubs in cancer evolution
Tài liệu tham khảo
Lugano, 2020, Tumor angiogenesis: causes, consequences, challenges and opportunities, Cell. Mol. Life Sci., 77, 1745, 10.1007/s00018-019-03351-7
Bao, 2006, Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor, Cancer Res., 66, 7843, 10.1158/0008-5472.CAN-06-1010
Cuypers, 2022, Tumor vessel co-option: the past & the future, Front. Oncol., 12, 10.3389/fonc.2022.965277
Nolan, 2007, Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization, Genes Dev., 21, 1546, 10.1101/gad.436307
Luo, 2020, Vasculogenic mimicry in carcinogenesis and clinical applications, J. Hematol. Oncol., 13, 1, 10.1186/s13045-020-00858-6
Maniotis, a. J., 1999, Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry, Am. J. Pathol., 155, 739, 10.1016/S0002-9440(10)65173-5
Carmeliet, 2011, Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases, Nat. Rev. Drug Discov., 10, 417, 10.1038/nrd3455
Nikolova, 2007, The vascular niche and its basement membrane, Trends Cell Biol., 17, 19, 10.1016/j.tcb.2006.11.005
Sahai, 2020, A framework for advancing our understanding of cancer-associated fibroblasts, Nat. Rev. Cancer, 20, 174, 10.1038/s41568-019-0238-1
Kalluri, 2006, Fibroblasts in cancer, Nat. Rev. Cancer, 6, 392, 10.1038/nrc1877
Butler, 2010, Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors, Nat. Rev. Cancer, 10, 138, 10.1038/nrc2791
Chotard-Ghodsnia, 2007, Morphological analysis of tumor cell/endothelial cell interactions under shear flow, J. Biomech., 40, 335, 10.1016/j.jbiomech.2006.01.001
Akino, 2009, Cytogenetic abnormalities of tumor-associated endothelial cells in human malignant tumors, Am. J. Pathol., 175, 2657, 10.2353/ajpath.2009.090202
Croix, 2000, Genes expressed in human tumor endothelium, Science, 289, 1197, 10.1126/science.289.5482.1197
Lambrechts, 2018, Phenotype molding of stromal cells in the lung tumor microenvironment, Nat. Med., 24, 1277, 10.1038/s41591-018-0096-5
Goveia, 2020, An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates, Cancer Cell, 37, 21, 10.1016/j.ccell.2019.12.001
Zeisberg, 2007, Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts, Cancer Res., 67, 10123, 10.1158/0008-5472.CAN-07-3127
Choi, 2018, Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization, Nat. Commun., 9, 5108, 10.1038/s41467-018-07470-w
Clere, 2020, Endothelial-to-mesenchymal transition in cancer, Front. Cell Dev. Biol., 8, 747, 10.3389/fcell.2020.00747
Ghiabi, 2015, Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche, J. Transl. Med., 13, 10.1186/s12967-015-0386-3
Ohmura-Kakutani, 2014, Identification of tumor endothelial cells with high aldehyde dehydrogenase activity and a highly angiogenic phenotype, PLoS One, 10.1371/journal.pone.0113910
Ohga, 2012, Heterogeneity of tumor endothelial cells: comparison between tumor endothelial cells isolated from high- and low-metastatic tumors, Am. J. Pathol., 180, 1294, 10.1016/j.ajpath.2011.11.035
Amersfoort, 2022, Immunomodulation by endothelial cells — partnering up with the immune system?, Nat. Rev. Immunol., 22, 576, 10.1038/s41577-022-00694-4
Demaria, 2015, STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity, Proc. Natl. Acad. Sci. U. S. A., 112, 15408, 10.1073/pnas.1512832112
Nagl, 2020, Tumor endothelial cells (TECs) as potential immune directors of the tumor microenvironment - new findings and future perspectives, Front. Cell Dev. Biol., 8, 766, 10.3389/fcell.2020.00766
Motz, 2014, Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors, Nat. Med., 20, 607, 10.1038/nm.3541
Sharma, 2020, Onco-fetal reprogramming of endothelial cells drives immunosuppressive macrophages in hepatocellular carcinoma, Cell, 183, 377, 10.1016/j.cell.2020.08.040
Georganaki, 2020, Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy, Oncoimmunology, 9, 10.1080/2162402X.2020.1730538
Geldhof, 2022, Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast, Nat. Commun., 13, 1, 10.1038/s41467-022-33052-y
Amoozgar, 2022, Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells, bioRxiv
Zhou, 2020, The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic–epigenetic reprogramming and resolves inflammatory injury, Nat. Immunol., 21, 1430, 10.1038/s41590-020-0764-8
Hendrix, 2003, Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma, Nat. Rev. Cancer, 3, 411, 10.1038/nrc1092
Fernández-Cortés, 2019, Vasculogenic mimicry: become an endothelial cell “but not so much”, Front. Oncol., 9, 803, 10.3389/fonc.2019.00803
van der Schaft, 2004, Effects of angiogenesis inhibitors on vascular network formation by human endothelial and melanoma cells, J. Natl. Cancer Inst., 96, 1473, 10.1093/jnci/djh267
Lai, 2012, CD133+ melanoma subpopulations contribute to perivascular niche morphogenesis and tumorigenicity through vasculogenic mimicry, Cancer Res., 72, 5111, 10.1158/0008-5472.CAN-12-0624
Wang, 2010, Glioblastoma stem-like cells give rise to tumour endothelium, Nature, 468, 829, 10.1038/nature09624
Wurmser, 2004, Cell fusion-independent differentiation of neural stem cells to the endothelial lineage, Nature, 430, 350, 10.1038/nature02604
Zhao, 2018, ETV2 mediates endothelial transdifferentiation of glioblastoma, Signal Transduct. Target. Ther., 3, 1, 10.1038/s41392-018-0007-8
Wagenblast, 2015, A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis, Nature, 520, 358, 10.1038/nature14403
Soda, 2011, Transdifferentiation of glioblastoma cells into vascular endothelial cells, Proc. Natl. Acad. Sci. U. S. A., 108, 4274, 10.1073/pnas.1016030108
Li, 2020, Disseminated melanoma cells transdifferentiate into endothelial cells in intravascular niches at metastatic sites, Cell Rep., 31, 10.1016/j.celrep.2020.107765
Beck, 2011, A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours, Nature, 478, 399, 10.1038/nature10525
Calabrese, 2007, A perivascular niche for brain tumor stem cells, Cancer Cell, 11, 69, 10.1016/j.ccr.2006.11.020
Karras, 2022, A cellular hierarchy in melanoma uncouples growth and metastasis, Nature, 610, 190, 10.1038/s41586-022-05242-7
Cao, 2014, Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance, 25, 350
Cao, 2017, Molecular checkpoint decisions made by subverted vascular niche transform indolent tumor cells into chemoresistant cancer stem cells, Cancer Cell, 31, 110, 10.1016/j.ccell.2016.11.010
Harrell, 2018, Molecular mechanisms underlying therapeutic potential of pericytes, J. Biomed. Sci., 25, 21, 10.1186/s12929-018-0423-7
Furuhashi, 2004, Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate, Cancer Res., 64, 2725, 10.1158/0008-5472.CAN-03-1489
Guo, 2003, Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment, Am. J. Pathol., 162, 1083, 10.1016/S0002-9440(10)63905-3
Hosaka, 2013, Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis, Nat. Commun., 4, 2129, 10.1038/ncomms3129
Barlow, 2013, Pericytes on the tumor vasculature: jekyll or hyde?, Cancer Microenviron., 6, 1, 10.1007/s12307-012-0102-2
Wong, 2020, Cancer burden is controlled by mural cell-β3-integrin regulated crosstalk with tumor cells, Cell, 181, 1346, 10.1016/j.cell.2020.02.003
Chen, 2016, Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells, Nat. Commun., 7, 12422, 10.1038/ncomms12422
Navarro, 2016, Immune regulation by pericytes: modulating innate and adaptive immunity, Front. Immunol., 7, 1, 10.3389/fimmu.2016.00480
Qian, 2009, A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth, PLoS One, 4, 10.1371/journal.pone.0006562
Pombero, 2023, Pericyte-glioblastoma cell interaction: a key target to prevent glioblastoma progression, Cells, 12, 1324, 10.3390/cells12091324
Yang, 2016, The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages, Nat. Commun., 7, 11385, 10.1038/ncomms11385
Zhang, 2022, Pericyte mediates the infiltration, migration, and polarization of macrophages by CD163/MCAM axis in glioblastoma, iScience, 25
Paiva, 2018, Pericytes in the premetastatic niche, Cancer Res., 78, 2779, 10.1158/0008-5472.CAN-17-3883
Prazeres, 2017, Pericytes are heterogeneous in their origin within the same tissue, Dev. Biol., 427, 6, 10.1016/j.ydbio.2017.05.001
Birbrair, 2014, Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner, Stem Cell Res. Ther., 5, 122, 10.1186/scrt512
Meng, 2021, Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities, Nat. Commun., 12, 1, 10.1038/s41467-021-26259-y
Hosaka, 2016, Pericyte-fibroblast transition promotes tumor growth and metastasis, Proc. Natl. Acad. Sci. U. S. A., 113, E5618, 10.1073/pnas.1608384113
Zhang, 2017, Malignant pericytes expressing GT198 give rise to tumor cells through angiogenesis, Oncotarget, 8, 51591, 10.18632/oncotarget.18196
Cho, 2003, Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation, FASEB J., 17, 440, 10.1096/fj.02-0340fje
Murgai, 2017, KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis, Nat. Med., 23, 1176, 10.1038/nm.4400
Stapor, 2012, Identification of class III β-tubulin as a marker of angiogenic perivascular cells, Microvasc. Res., 83, 257, 10.1016/j.mvr.2011.09.003
Berger, 2005, Regulator of G-protein signaling-5 induction in pericytes coincides with active vessel remodeling during neovascularization, Blood, 105, 1094, 10.1182/blood-2004-06-2315
Vries, 2000, The regulator of G protein signaling family, Annu. Rev. Pharmacol. Toxicol., 40, 235, 10.1146/annurev.pharmtox.40.1.235
Hamzah, 2008, Vascular normalization in Rgs5-deficient tumours promotes immune destruction, Nature, 453, 410, 10.1038/nature06868
Lugassy, 2014, Angiotropism, pericytic mimicry and extravascular migratory metastasis in melanoma: an alternative to intravascular cancer dissemination, Cancer Microenviron., 7, 139, 10.1007/s12307-014-0156-4
Lugassy, 2013, Pilot study on “pericytic mimicry” and potential embryonic/stem cell properties of angiotropic melanoma cells interacting with the abluminal vascular surface, Cancer Microenviron., 6, 19, 10.1007/s12307-012-0128-5
Rajan, 2020, Dual function of perivascular fibroblasts in vascular stabilization in zebrafish, PLoS Genet., 16, 10.1371/journal.pgen.1008800
Bertero, 2019, Tumor-stroma mechanics coordinate amino acid availability to sustain tumor growth and malignancy, Cell Metab., 29, 124, 10.1016/j.cmet.2018.09.012
Ippolito, 2019, Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer, Oncogene, 38, 5339, 10.1038/s41388-019-0805-7
Plaks, 2015, The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?, Cell Stem Cell, 16, 225, 10.1016/j.stem.2015.02.015
Rudnick, 2011, Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells, PLoS One, 6, 10.1371/journal.pone.0024605
Elyada, 2019, Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts, Cancer Discov., 9, 1102, 10.1158/2159-8290.CD-19-0094
Barrett, 2020, Cancer-associated fibroblasts and their influence on tumor immunity and immunotherapy, eLife, 9, 10.7554/eLife.57243
Calvo, 2013, Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts, Nat. Cell Biol., 15, 637, 10.1038/ncb2756
Sewell-Loftin, 2017, Cancer-associated fibroblasts support vascular growth through mechanical force, Sci. Rep., 7, 10.1038/s41598-017-13006-x
Costa, 2018, Fibroblast heterogeneity and immunosuppressive environment in human breast cancer, Cancer Cell, 33, 463, 10.1016/j.ccell.2018.01.011
Luo, 2022, Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment, Nat. Commun., 13, 6619, 10.1038/s41467-022-34395-2
Verginadis, 2022, A stromal integrated stress response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression, Nat. Cell Biol., 24, 940, 10.1038/s41556-022-00918-8
Lo, 2015, Tumor-promoting desmoplasia is disrupted by depleting FAP-expressing stromal cells, Cancer Res., 75, 2800, 10.1158/0008-5472.CAN-14-3041
Mao, 2021, Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives, Mol. Cancer, 20, 131, 10.1186/s12943-021-01428-1
Kumar, 2017, Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors, Cancer Cell, 32, 654, 10.1016/j.ccell.2017.10.005
Huang, 2022, Targeting cancer-associated fibroblast-secreted WNT2 restores dendritic cell-mediated antitumour immunity, Gut, 71, 333, 10.1136/gutjnl-2020-322924
Massagué, 2021, Metastasis-initiating cells and ecosystems, Cancer Discov., 11, 971, 10.1158/2159-8290.CD-21-0010
Xian, 2006, Pericytes limit tumor cell metastasis, J. Clin. Invest., 116, 642, 10.1172/JCI25705
Yonenaga, 2005, Absence of smooth muscle actin-positive pericyte coverage of tumor vessels correlates with hematogenous metastasis and prognosis of colorectal cancer patients, Oncology, 69, 159, 10.1159/000087840
Cooke, 2012, Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway, Cancer Cell, 21, 66, 10.1016/j.ccr.2011.11.024
Harney, 2015, Real-time imaging reveals local, transient vascular permeability, and tumor cell intravasation stimulated by TIE2hi macrophage-derived VEGFA, Cancer Discov., 5, 932, 10.1158/2159-8290.CD-15-0012
Rossi, 2022, PHGDH heterogeneity potentiates cancer cell dissemination and metastasis, Nature, 605, 747, 10.1038/s41586-022-04758-2
Kienast, 2010, Real-time imaging reveals the single steps of brain metastasis formation, Nat. Med., 16, 116, 10.1038/nm.2072
Ubellacker, 2020, Lymph protects metastasizing melanoma cells from ferroptosis, Nature, 585, 113, 10.1038/s41586-020-2623-z
Melo, 2017, A distinct role for Lgr5 + stem cells in primary and metastatic colon cancer, Nature, 543, 676, 10.1038/nature21713
Strilic, 2016, Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis, Nature, 536, 215, 10.1038/nature19076
Malladi, 2016, Metastatic latency and immune evasion through autocrine inhibition of WNT, Cell, 165, 45, 10.1016/j.cell.2016.02.025
Molnár, 2020, Pericyte-secreted IGF2 promotes breast cancer brain metastasis formation, Mol. Oncol., 14, 2040, 10.1002/1878-0261.12752
Er, 2018, Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization, Nat. Cell Biol., 20, 966, 10.1038/s41556-018-0138-8
Al-Mehdi, 2000, Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis, Nat. Med., 6, 100, 10.1038/71429
Bald, 2014, Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma, Nature, 507, 109, 10.1038/nature13111
Kang, 2021, Tenascin-c knockdown suppresses vasculogenic mimicry of gastric cancer by inhibiting ERK- triggered EMT, Cell Death Dis., 12, 890, 10.1038/s41419-021-04153-1
Yang, 2019, Tenascin-C is involved in promotion of cancer stemness via the Akt/HIF1α axis in esophageal squamous cell carcinoma, Exp. Mol. Pathol., 109, 10.1016/j.yexmp.2019.03.007
Sun, 2018, Tenascin-C promotes tumor cell migration and metastasis through integrin α9β1-mediated YAP inhibition, Cancer Res., 78, 950, 10.1158/0008-5472.CAN-17-1597
Hongu, 2022, Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs, Nat. Can., 3, 486, 10.1038/s43018-022-00353-6
Hambardzumyan, 2008, PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo, Genes Dev., 22, 436, 10.1101/gad.1627008
Carlson, 2019, Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy, Nat. Cell Biol., 21, 238, 10.1038/s41556-018-0267-0
Ghajar, 2015, Metastasis prevention by targeting the dormant niche, Nat. Rev. Cancer, 15, 238, 10.1038/nrc3910
Ghajar, 2013, The perivascular niche regulates breast tumour dormancy, Nat. Cell Biol., 15, 807, 10.1038/ncb2767
Oshimori, 2015, TGF-β promotes heterogeneity and drug resistance in squamous cell carcinoma, Cell, 160, 963, 10.1016/j.cell.2015.01.043
Zhu, 2011, Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells, Cancer Res., 71, 6061, 10.1158/0008-5472.CAN-10-4269
Gering, 2008, Notch in the niche, Cell Stem Cell, 2, 293, 10.1016/j.stem.2008.03.016
Majumder, 2021, Targeting Notch in oncology: the path forward, Nat. Rev. Drug Discov., 20, 125, 10.1038/s41573-020-00091-3
Ridgway, 2006, Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis, Nature, 444, 1083, 10.1038/nature05313
Noguera-Troise, 2006, Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis, Nature, 444, 1032, 10.1038/nature05355
Liu, 2023, Angiogenic signaling pathways and anti-angiogenic therapy for cancer, Signal Transduct. Target. Ther., 8, 198, 10.1038/s41392-023-01460-1
Zhou, 2022, Notch signaling pathway: architecture, disease, and therapeutics, Signal Transduct. Target. Ther., 7, 95, 10.1038/s41392-022-00934-y
Boyerinas, 2013, Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy, Blood, 121, 4821, 10.1182/blood-2012-12-475483
Khoo, 2019, A niche-dependent myeloid transcriptome signature defines dormant myeloma cells, Blood, 134, 30, 10.1182/blood.2018880930
Dai, 2020, Exosomes: key players in cancer and potential therapeutic strategy, Signal Transduct. Target. Ther., 5, 145, 10.1038/s41392-020-00261-0
Hua, 2022, Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop, Cancer Cell, 40, 1600, 10.1016/j.ccell.2022.11.002
Marturano-Kruik, 2018, Human bone perivascular niche-on-a-chip for studying metastatic colonization, Proc. Natl. Acad. Sci. U. S. A., 115, 1256, 10.1073/pnas.1714282115
Ngo, 2022, Perivascular stromal cells instruct glioblastoma invasion, proliferation, and therapeutic response within an engineered brain perivascular niche model, Adv. Sci. Lett., 9