Periprandial changes and effects of short- and long-term fasting on ghrelin, GOAT, and ghrelin receptors in goldfish (Carassius auratus)

Amole N, Unniappan S (2009) Fasting induces preproghrelin mRNA expression in the brain and gut of zebrafish, Danio rerio. Gen Comp Endocrinol 161:133–137 Ariyasu H, Takaya K, Hosoda H, Iwakura H, Ebihara K, Mori K, Ogawa Y, Hosoda K, Akamizu T, Kojima M, Kangawa K, Nakao K (2002) Delayed short-term secretory regulation of ghrelin in obese animals:evidenced by a specific RIA for the active form of ghrelin. Endocrinology 143:3341–3350 Arisayu H, Takaya K, Tagami T, Ogawa Y, Hosoda K, Akamizu T, Suda M, Koh T, Natsui K, Toyooka S, Shirakami G, Usui T, Shimatsu A, Doi K, Hosoda H, Kojima M, Kangawa K, Nakao K (2001) Stomach is the major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab 86:4753–4758 Breves JP, Veillette PA, Specker JL (2009) Ghrelin in the summer flounder: immunolocalization to the gastric glands and action on plasma cortisol levels. Comp Biochem Physiol A Mol Integr Physiol 152:268–272 Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS (2001) A preprandial rise in ghrelin levels suggests a role in meal initiation in humans. Diabetes 50:1714–1719 Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, Grove KL, Strasburger CJ et al (2003) The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 37:649–661 Delhanty PJD, Neggers SJ, van der Lely AJ (2012) Ghrelin: the differences between acyl- and des-acyl-ghrelin. Eur J Endocrinol 167:601–608 Delporte C (2013) Structure and physiological actions of ghrelin. Scientifica 2013:1–25 Eom J, Hong M, Cone RD, Song Y (2013) Zebrafish ghrelin is expressed in pancreatic endocrine cells and regulated by metabolic state. Biochem Biophys Res Commun 439:115–120 Eom J, Hong A, Kang YH, Yoo HJ, Chang EJ, Kang SW, Yoon SY, Kim SY, Song Y (2014) Molecular cloning, regulation, and functional analysis of two GHS-R genes in zebrafish. Exp Cell Res 326:10–21 Feng K, Zhang GR, Wei KJ, Xiong BX (2013) Molecular cloning, tissue distribution, and ontogenetic expression of ghrelin and regulation of expression by fasting and refeeding in the grass carp (Ctenopharyngodon idellus). J Exp Zool Part Ecol Genet Physiol 319:202–212 Fox BK, Breves JP, Hirano T, Grau EG (2009) Effects of short- and long-term fasting on plasma and stomach ghrelin, and the growth hormone/insulin-like growth factor I axis in the tilapia, Oreochromis mossambicus. Domest Anim Endocrinol 37:1–11 Gahete MD, Córdoba-Chacón J, Salvatori R, Castaño JP, Kineman RD, Luque RM (2010) Metabolic regulation of ghrelin O-acyl transferase (GOAT) expression in the mouse hypothalamus, pituitary, and stomach. Mol Cell Endocrinol 317:154–160 Gauna C, Delhanty PJ, Hofland LJ, Janssen JA, Broglio F, Ross RJ, Ghigo E, van der Lely AJ (2005) Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes. J Clin Endocrinol Metab 90:1055–1060 Gauna C, Kiewiet RM, Janssen JAMJL, van de Zande B, Delhanty PJD, Ghigo E, Hofland LJ, Themmen APN, van der Lely AJ (2007) Unacylated ghrelin acts as a potent insulin secretagogue in glucose-stimulated conditions. Am J Physiol Endocrinol Metab 293:E697–E704 González CR, Vázquez MJ, López M, Diéguez C (2008) Influence of chronic undernutrition and leptin on GOAT mRNA levels in rat stomach mucosa. J Mol Endocrinol 41:415–421 Gutierrez JA, Solenberg PJ, Perkins DR, Willency JA, Knierman MD, Jin Z, Witcher DR, Luo S, Onyia JE, Hale JE (2008) Ghrelin octanoylation mediated by an orphan lipid transferase. Proc Natl Acad Sci USA 105:6320–6325 Hatef A, Yufa R, Unniappan S (2015) Ghrelin O-acyl transferase in zebrafish is an evolutionarily conserved peptide upregulated during calorie restriction. Zebrafish 12:327–338 Heppner KM, Tong J, Kirchner H, Nass R, Tschöp MH (2011) The ghrelin O-acyltransferase–ghrelin system: a novel regulator of glucose metabolism. Curr Opin Endocrinol Diabetes Obes 18:50–55 Hevrøy EM, Azpeleta C, Shimizu M, Lanzén A, Kaiya H, Espe M, Olsvik PA (2011) Effects of short-term starvation on ghrelin, GH-IGF system, and IGF-binding proteins in Atlantic salmon. Fish Physiol Biochem 37:217–232 Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M et al (1996) A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 273:974–977 Inhoff T, Wiedenmann B, Klapp BF, Mönnikes H, Kobelt P (2009) Is desacyl ghrelin a modulator of food intake?. Peptides 30:991–994 Jönsson E, Forsman A, Einarsdottir IE, Kaiya H, Ruohonen K, Björnsson BT (2007) Plasma ghrelin levels in rainbow trout in response to fasting, feeding and food composition, and effects of ghrelin on voluntary food intake. Comp Biochem Physiol A Mol Integr Physiol 147:1116–1124 Kaiya H, Kojima M, Hosoda H, Moriyama S, Takahashi A, Kawauchi H, Kangawa K (2003) Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. Endocrinology 144:5215–5226 Kaiya H, Miyazato M, Kangawa K, Peter RE, Unniappan S (2008) Ghrelin: a multifunctional hormone in non-mammalian vertebrates. Comp Biochem Physiol A Mol Integr Physiol 149:109–128 Kaiya H, Miura T, Matsuda K, Miyazato M, Kangawa K (2010) Two functional growth hormone secretagogue receptor (ghrelin receptor) type 1a and 2a in goldfish, Carassius auratus. Mol Cell Endocrinol 327:25–39 Kaiya H, Kangawa K, Miyazato M (2013) Ghrelin receptors in non-mammalian vertebrates. Front Endocrinol 4:81 Kirchner H, Gutierrez JA, Solenberg PJ, Pfluger PT, Czyzyk TA, Willency JA, Schürmann A, Joost HG, Jandacek RJ, Hale JE, Heiman ML, Tschöp MH (2009) GOAT links dietary lipids with the endocrine control of energy balance. Nat Med 15:741–745 Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K (1999) Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:656–660 Korhonen T, Saarela S (2005) Role of adiposity hormones in the mouse during fasting and winter-acclimatization. Comp Biochem Physiol A Mol Integr Physiol 140:217–223 Koven W, Schulte P (2012) The effect of fasting and refeeding on mRNA expression of PepT1 and gastrointestinal hormones regulating digestion and food intake in zebrafish (Danio rerio). Fish Physiol Biochem 38:1565–1575 Larhammar D, Risinger C (1994) Molecular aspects of tetraploidy in the common carp Cyprinus carpio. Mol Phylogenet Evol 3:59–68 Lear PV, Iglesias MJ, Feijóo-Bandín S, Rodríguez-Penas D, Mosquera-Leal A, García-Rúa V, Gualillo O et al (2010) Des-acyl-ghrelin has specific binding sites and different metabolic effects from ghrelin in cardiomyocytes. Endocrinology 151:3286–3298 Lim CT, Kola B, Korbonits M (2011) The ghrelin/GOAT/GHS-R system and energy metabolism. Rev Endocr Metab Disord 12:173–186 Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402–408 Matsuda K, Miura T, Kaiya H, Maruyama K, Uchiyama M, Kangawa K, Shioda S (2006a) Stimulatory effect of n-octanoylated ghrelin on locomotor activity in the goldfish, Carassius auratus. Peptides 27:1335–1340 Matsuda K, Miura T, Kaiya H, Maruyama K, Shimakura SI, Uchiyama M, Kangawa K, Shioda S (2006b) Regulation of food intake by acyl and des-acyl-ghrelins in the goldfish. Peptides 27:2321–2325 Miura T, Maruyama K, Kaiya H, Miyazato M, Kangawa K, Uchiyama M, Shioda S, Matsuda K (2009) Purification and properties of ghrelin from the intestine of the goldfish, Carassius auratus. Peptides 30:758–765 Müller TD, Nogueiras R, Andermann ML, Andrews ZB, Anker SD, Argente J, Batterham RL et al (2015) Ghrelin. Mol Metab 4:437–460 Pankhurst NW, King HR, Ludke SL (2008) Relationship between stress, feeding and plasma ghrelin levels in rainbow trout, Oncorhynchus mykiss. Mar Freshw Behav Physiol 41:53–64 Peddu SC, Breves JP, Kaiya H, Grau EG, Riley LG Jr (2009) Pre- and postprandial effects on ghrelin signaling in the brain and on the GH/IGF-I axis in the Mozambique tilapia (Oreochromis mossambicus). Gen Comp Endocrinol 161:412–418 Picha ME, Strom CN, Riley LG, Walker AA, Won ET, Johnstone WM, Borski RJ (2009) Plasma ghrelin and growth hormone regulation in response to metabolic state in hybrid striped bass: Effects of feeding, ghrelin and insulin-like growth factor-I on in vivo and in vitro GH secretion. Gen Comp Endocrinol 161:365–372 Riley LG, Fox BK, Breves JP, Kaiya H, Dorough CP, Hirano T, Grau EG (2008) Absence of effects of short-term fasting on plasma ghrelin and brain expression of ghrelin receptors in the tilapia, Oreochromis mossambicus. Zool Sci 25:821–827 Sánchez-Bretaño A, Blanco AM, Unniappan S, Kah O, Gueguen M-M, Bertucci JI, Alonso-Gómez AL, Valenciano AI, Isorna E, Delgado MJ (2015) In situ localization and rhythmic expression of ghrelin and ghs-r1 ghrelin receptor in the brain and gastrointestinal tract of goldfish (Carassius auratus). PLoS One 10:e0141043 Sato M, Nakahara K, Goto S, Kaiya H, Miyazato M, Date Y, Nakazato M, Kangawa K, Murakami N (2006) Effects of ghrelin and des-acyl ghrelin on neurogenesis of the rat fetal spinal cord. Biochem Biophys Res Commun 350:598–603 Sato T, Nakamura Y, Shiimura Y, Ohgusu H, Kangawa K, Kojima M (2012) Structure, regulation and function of ghrelin. J Biochem 151:119–128 Terova G, Rimoldi S, Bernardini G, Gornati R, Saroglia M (2008) Sea bass ghrelin: molecular cloning and mRNA quantification during fasting and refeeding. Gen Comp Endocrinol 155:341–351 Unniappan S, Lin X, Cervini L, Rivier J, Kaiya H, Kangawa K, Peter RE (2002) Goldfish ghrelin: molecular characterization of the complementary deoxyribonucleic acid, partial gene structure and evidence for its stimulatory role in food intake. Endocrinology 143:4143–4146 Unniappan S, Canosa LF, Peter RE (2004) Orexigenic actions of ghrelin in goldfish: feeding-induced changes in brain and gut mRNA expression and serum levels, and responses to central and peripheral injections. Neuroendocrinology 79:100–108 Yang J, Brown MS, Liang G, Grishin NV, Goldstein JL (2008) Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 132:387–396 Zhao Z, Sakata I, Okubo Y, Koike K, Kangawa K, Sakai T (2008) Gastric leptin, but not estrogen and somatostatin, contributes to the elevation of ghrelin mRNA expression level in fasted rats. J Endocrinol 196:529–538 Zhou C, Zhang X, Liu T, Wei R, Yuan D, Wang T, Lin F et al (2014) Schizothorax davidi ghrelin: cDNA cloning, tissue distribution and indication for its stimulatory character in food intake. Gene 534:72–77