Nguồn gốc ít ngày của tế bào gốc trung mô: Thạch Wharton, màng ối và màng đệm

Małgorzata Witkowska-Zimny1, Edyta Wróbel1
1Department of Biophysics and Human Physiology, Medical University of Warsaw, Chalubinskiego 5, 02-004 Warsaw, Poland

Tóm tắt

Tóm tắt

Gần đây, sinh học tế bào gốc đã trở thành một chủ đề thú vị, đặc biệt trong bối cảnh điều trị bệnh tật và chấn thương bằng liệu pháp ghép tế bào. Nhiều loại tế bào gốc người đã được phân lập và xác định cả trong cơ thể và ngoài cơ thể. Lý tưởng nhất, tế bào gốc cho ứng dụng y học tái sinh nên được tìm thấy với số lượng phong phú, thu hoạch qua quy trình xâm lấn tối thiểu, và sau đó được cấy ghép an toàn và hiệu quả vào chủ thể tự thân hoặc dị thân. Hai nhóm tế bào gốc chính, tế bào gốc phôi và tế bào gốc trưởng thành, đã được mở rộng để bao gồm các tế bào gốc từ thời kỳ sau sinh. Tế bào gốc trung mô từ mô sau sinh có thể rất hữu ích trong lâm sàng cho ghép tự thân cho thai nhi và trẻ sơ sinh, và sau khi lưu trữ ở các giai đoạn sau của cuộc đời, cũng như cho ghép trong tử cung trong trường hợp rối loạn di truyền.

Bài đánh giá này làm nổi bật các đặc điểm và tiềm năng điều trị của ba loại tế bào gốc trung mô người thu được từ các nguồn sau sinh: thạch Wharton, màng ối và màng đệm.

Từ khóa


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