Perception Versus Reality?: Virtual Crossmatch—How to Overcome Some of the Technical and Logistic Limitations

American Journal of Transplantation - Tập 9 - Trang 1886-1893 - 2009
A.R. Tambur1,2, D.S. Ramon1, D.B. Kaufman2, J. Friedewald3, X. Luo3, B. Ho3, A. Skaro2, J. Caicedo2, D. Ladner2, T. Baker2, J. Fryer2, L. Gallon3, J. Miller2, M.M. Abecassis2, J. Leventhal2
1Transplant Immunology Laboratory
2Division of Organ Transplantation, Department of Surgery
3Department of Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL

Tài liệu tham khảo

Pei, 2003, Single human leukocyte antigen flow cytometry beads for accurate identification of human leukocyte antigen antibody specificities, Transplantation, 75, 43, 10.1097/00007890-200301150-00008 El-Awar, 2005, HLA antibody identification with single antigen beads compared to conventional methods, Hum Immunol, 66, 989, 10.1016/j.humimm.2005.07.005 Cherikh WSBT, Nelson K, Land G, Leffell M, Nikaein A. Broader geographic sharing through accurate prediction of crossmatch results. AJT 2006; World Transplant Congress (Abstract) # 868 360. Cherikh W. Variability of PRA levels and reporting of unacceptable antigens among transplant centers. Report to the Histocompatibility Committee on January 26, 2006 of an analysis of OPTN/UNOS data Ho, 2008, Sensitivity, specificity and clinical relevance of different cross-matching assays in deceased-donor renal transplantation, Transpl Immunol, 20, 61, 10.1016/j.trim.2008.09.013 Van Den Berg-Loonen, 2008, Clinical relevance of pretransplant donor-directed antibodies detected by single antigen beads in highly sensitized renal transplant patients, Transplantation, 85, 1086, 10.1097/TP.0b013e31816b3ed1 Zachary, 2008, Antibody monitoring: A solid approach to predicting clinical outcome, Transplantation, 86, 768, 10.1097/TP.0b013e3181856ffa Available at: http://www.unos.org/SharedContentDocuments/CPRA_Professionals.pdf.In Zangwill, 2006, The virtual crossmatch–a screening tool for sensitized pediatric heart transplant recipients, Pediatr Transplant, 10, 38, 10.1111/j.1399-3046.2005.00394.x Bielmann, 2007, Pretransplant risk assessment in renal allograft recipients using virtual crossmatching, Am J Transplant, 7, 626, 10.1111/j.1600-6143.2007.01667.x Gupta, 2008, Pretransplant donor-specific antibodies in cytotoxic negative crossmatch kidney transplants: Are they relevant?, Transplantation, 85, 1200, 10.1097/TP.0b013e31816b1c37 Vaidya, 2006, Prediction of crossmatch outcome of highly sensitized patients by single and/or multiple antigen bead luminex assay, Transplantation, 82, 1524, 10.1097/01.tp.0000246311.43634.0a Zangwill, 2007, Practical application of the virtual crossmatch, Pediatr Transplant, 11, 650, 10.1111/j.1399-3046.2007.00746.x Vaidya, 2008, Clinical importance of anti-human leukocyte antigen-specific antibody concentration in performing calculated panel reactive antibody and virtual crossmatches, Transplantation, 85, 1046, 10.1097/TP.0b013e318168fdb5 Appel, 2006, Role of flow cytometry to define unacceptable HLA antigens in lung transplant recipients with HLA-specific antibodies, Transplantation, 81, 1049, 10.1097/01.tp.0000204046.89396.c5 Reinsmoen, 2008, Acceptable donor-specific antibody levels allowing for successful deceased and living donor kidney transplantation after desensitization therapy, Transplantation, 86, 820, 10.1097/TP.0b013e3181856f98 Available at: www.asts.org/Tools/Download.aspx–fid=760.in Tambur, 2008, Tailoring antibody testing and how to use it in the calculated panel reactive antibody era: The Northwestern University experience, Transplantation, 86, 1052, 10.1097/TP.0b013e3181874b06 Owens, 2008, A case of antibody mediated rejection from anti-donor HLA-Cw antibody., Hum Immunol, 69, S123, 10.1016/j.humimm.2008.08.255 Warner, 2008, Comparing the UNOS/OPTN CPRA system vs. local CPRA system, Hum Immunol, 69, S108, 10.1016/j.humimm.2008.08.224 Zoet, 2004, HLA-Cw specific antibodies and kidney transplantation, [Abstract] Transplantation, 78, 483 Bray, 2004, Evolution of HLA antibody detection: Technology emulating biology, Immunol Res, 29, 41, 10.1385/IR:29:1-3:041 Kerman, 1999, Flow cytometry-detected IgG is not a contraindication to renal transplantation: IgM may be beneficial to outcome, Transplantation, 68, 1855, 10.1097/00007890-199912270-00007 Karpinski, 2001, Flow cytometric crossmatching in primary renal transplant recipients with a negative anti-human globulin enhanced cytotoxicity crossmatch, J Am Soc Nephrol, 12, 2807, 10.1681/ASN.V12122807 Scornik, 2001, Outcome of kidney transplants in patients known to be flow cytometry crossmatch positive, Transplantation, 71, 1098, 10.1097/00007890-200104270-00015 Cho YW, Cecka JM. Crossmatch tests-an analysis of UNOS data from 1991–2000. Clin Transpl 2001: 237–246. Higgins, 2007, Blood levels of donor-specific human leukocyte antigen antibodies after renal transplantation: Resolution of rejection in the presence of circulating donor-specific antibody, Transplantation, 84, 876, 10.1097/01.tp.0000284729.39137.6e Gebel, 2002, Conundrums with FlowPRA beads, Clin Transplant, 16, 24, 10.1034/j.1399-0012.16.s7.3.x Lefaucheur, 2009, Clinical relevance of preformed HLA donor-specific antibodies in kidney transplantation, Contrib Nephrol, 162, 1 Crew, 2005, Overcoming immunologic incompatibility: Transplanting the difficult to transplant patient, Semin Dial, 18, 474, 10.1111/j.1525-139X.2005.00092.x Patel, 2007, Renal transplantation in patients with pre-transplant donor-specific antibodies and negative flow cytometry crossmatches, Am J Transplant, 7, 2371, 10.1111/j.1600-6143.2007.01944.x Lefaucheur, 2008, Clinical relevance of preformed HLA donor-specific antibodies in kidney transplantation, Am J Transplant, 8, 324, 10.1111/j.1600-6143.2007.02072.x Noreen, 2003, Positive remote crossmatch: Impact on short-term and long-term outcome in cadaver renal transplantation, Transplantation, 75, 501, 10.1097/01.TP.0000048225.98745.64 Gloor, 2004, Persistence of low levels of alloantibody after desensitization in crossmatch-positive living-donor kidney transplantation, Transplantation, 78, 221, 10.1097/01.TP.0000128516.82593.47 Williams, 2004, Acute vascular rejection and accommodation: Divergent outcomes of the humoral response to organ transplantation, Transplantation, 78, 1471, 10.1097/01.TP.0000140770.81537.64 Salama, 2001, Transplant accommodation in highly sensitized patients: A potential role for Bcl-xL and alloantibody, Am J Transplant, 1, 260, 10.1034/j.1600-6143.2001.001003260.x Salama, 2001, Challenges to achieving clinical transplantation tolerance, J Clin Invest, 108, 943, 10.1172/JCI200114142 Gloor, 2006, Histologic findings one year after positive crossmatch or ABO blood group incompatible living donor kidney transplantation, Am J Transplant, 6, 1841, 10.1111/j.1600-6143.2006.01416.x Haas, 2007, Subclinical acute antibody-mediated rejection in positive crossmatch renal allografts, Am J Transplant, 7, 576, 10.1111/j.1600-6143.2006.01657.x Jin, 2004, Anti-HLA class I antibody-mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells, Hum Immunol, 65, 291, 10.1016/j.humimm.2004.01.002 Jindra, 2006, Anti-HLA antibodies can induce endothelial cell survival or proliferation depending on their concentration, Transplantation, 82, S33, 10.1097/01.tp.0000231447.34240.3c Jindra, 2008, Anti-MHC class I antibody activation of proliferation and survival signaling in murine cardiac allografts, J Immunol, 180, 2214, 10.4049/jimmunol.180.4.2214 Gebel, 2003, Pre-transplant assessment of donor-reactive, HLA-specific antibodies in renal transplantation: Contraindication vs, risk. Am J Transplant, 3, 1488, 10.1046/j.1600-6135.2003.00273.x