Pediatric Septic Shock

Bone, 1992, Definitions for sepsis and organ failure, Crit Care Med, 20, 724, 10.1097/00003246-199206000-00002 Levy, 2003, 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference, Intensive Care Med, 29, 530, 10.1007/s00134-003-1662-x Hazelzet, 1996, Age-related differences in outcome and severity of DIC in children with septic shock and purpura, Thromb Haemost, 76, 932, 10.1055/s-0038-1650688 Anderson, 1997, Advances in the therapy for sepsis in children, Pediatr Clin North Am, 44, 179, 10.1016/S0031-3955(05)70469-7 Martinot, 1997, Sepsis in neonates and children: Definitions, epidemiology, and outcome, Pediatr Emerg Care, 13, 277, 10.1097/00006565-199708000-00011 Despond, 2001, Pediatric sepsis and multiple organ dysfunction syndrome, Curr Opin Pediatr, 13, 247, 10.1097/00008480-200106000-00006 DuPont, 1969, Infections due to Gram-negative organisms: An analysis of 860 patients with bacteremia at the University of Minnesota Medical Center, 1958-1966, Medicine, 48, 307, 10.1097/00005792-196907000-00003 Stoll, 1998, Decline in sepsis-associated neonatal and infant deaths in the United States, 1979 through 1994, Pediatrics, 102, e18, 10.1542/peds.102.2.e18 Watson, 2003, The epidemiology of severe sepsis in children in the United States, Am J Respir Crit Care Med, 167, 695, 10.1164/rccm.200207-682OC Pollard, 1999, Emergency management of meningococcal disease, Arch Dis Child, 80, 290, 10.1136/adc.80.3.290 Kanter, 1986, Pediatric emergency intravenous access. Evaluation of a protocol, Am J Dis Child, 140, 132, 10.1001/archpedi.1986.02140160050030 Ngo, 2001, Acute management of dengue shock syndrome: A randomized double-blind comparison of 4 intravenous fluid regimens in the first hour, Clin Infect Dis, 32, 204, 10.1086/318479 Carcillo, 1991, Role of early fluid resuscitation in pediatric septic shock, JAMA, 266, 1242, 10.1001/jama.1991.03470090076035 Powell, 1991, Normalization of plasma arginine vasopressin concentrations when children with meningitis are given maintenance plus replacement fluid therapy, J Pediatr, 117, 515, 10.1016/S0022-3476(05)80682-1 Ceneviva, 1998, Hemodynamic support in fluid-refractory pediatric septic shock, Pediatrics, 102, e19, 10.1542/peds.102.2.e19 Keeley, 1988, The use of inotropic and afterload-reducing agents in neonates, Clin Perinatol, 15, 467, 10.1016/S0095-5108(18)30692-4 Roberts, 1997, Inhaled nitric oxide and persistent pulmonary hypertension of the new born. Inhaled Nitric Oxide Study Group, N Engl J Med, 336, 605, 10.1056/NEJM199702273360902 Barton, 1996, Hemodynamic effects of i. v. milrinone lactate in pediatric patients with septic shock. A prospective, double-blinded, randomized, placebo-controlled, interventional study, Chest, 109, 1302, 10.1378/chest.109.5.1302 Lindsay, 1998, Pharmacokinetics and pharmacodynamics of milrinone lactate in pediatric patients with septic shock, J Pediatr, 132, 329, 10.1016/S0022-3476(98)70454-8 Irazuzta, 2001, Amrinone in paediatric refractory septic shock: An open-label pharma-codynamic study, PediatrCrit Care Med, 2, 24, 10.1097/00130478-200101000-00006 De Kleijn, 2002, Low serum cortisol in combination with high adrenocorticotrophic hormone concentrations are associated with poor outcomein children with severe meningococcal disease, Pediatr Infect Dis J, 21, 330, 10.1097/00006454-200204000-00013 Riordan, 1999, Admission cortisol and adrenocorticotrophic hormone levels in children with meningococcal disease: Evidence of adrenal insufficiency?, Crit Care Med, 27, 2257, 10.1097/00003246-199910000-00032 Hazelzet, 2001, Endothelial protein C activation in meningococcal sepsis, N Engl J Med, 345, 1776, 10.1056/NEJM200112133452413 de Kleijn, 2003, Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: A randomized, double-blinded, placebo-controlled, dose-finding study, Crit Care Med, 31, 1839, 10.1097/01.CCM.0000072121.61120.D8 Bilgin, 2001, A randomized trial of granulocyte-macrophage colony-stimulating factor in neonates with sepsis and neutropenia, Pediatrics, 107, 36, 10.1542/peds.107.1.36 La Gamma, 2002, What is the rationale for the use of granulocyte and granulocyte-macrophage colonystimulating factors in the neonatal intensive care unit?, Acta Paediatr Suppl, 91, 109, 10.1111/j.1651-2227.2002.tb02914.x Chaïbou, 1998, Clinically significant upper gastrointestinal bleeding acquired in a pediatric intensive care unit: A prospective study, Pediatrics, 102, 933, 10.1542/peds.102.4.933 Gauvin, 2001, The impact of clinically significant upper gastrointestinal bleeding in a paediatric intensive care unit, Paediatr Crit Care Med, 2, 294, 10.1097/00130478-200110000-00002 Alejandria, 2002, Intravenous immunoglobulin for treating sepsis and septic shock, Cochrane Database Syst Rev, 1, CD001090 Meyer, 1997, Results of extracorporeal membrane oxygenation in children with sepsis. The Extracorporeal LifeSupport Organization, Ann Thorac Surg, 63, 756, 10.1016/S0003-4975(96)01272-6 Goldman, 1997, Extracorporeal support for intractable cardiorespiratory failure due to meningococcal disease, Lancet, 349, 466, 10.1016/S0140-6736(96)12106-1 Brochard, 1994, Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation, Am J Respir Crit Care Med, 150, 896, 10.1164/ajrccm.150.4.7921460