Pediatric Inflammatory Myofibroblastic Tumor with Late Metastasis to the Lung: Case Report and Review of the Literature

SAGE Publications - Tập 8 Số 2 - Trang 224-229 - 2005
Raffaella Morotti1, Michael D. Legman1, Nanda Kerkar2, Bruce Pawel3, Warren G. Sanger4, Cheryl M. Coffin5
1Department of Pathology, Box 1194, Mount Sinai Medical Center, One Gustave L. Levy Place, New York, NY 10029, USA
2Recanati-Miller Transplant Institute and Division of Hepatology, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA
3Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine and The Children's Hospital of Philadelphia, Philadelphia, PA, USA
4Department of Pediatrics and Pathology, Human Genetics Laboratories, Munroe-Mayer Institute, Nebraska Medical Center, Omaha, NE, USA
5Department of Pediatric Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA

Tóm tắt

Inflammatory myofibroblastic tumors (IMTs) are challenging lesions with respect to classification, differential diagnosis, and biologic potential. In children, extrapulmonary IMTs, particularly those from the abdomen or mesentery, are generally aggressive, with frequent local recurrences. There are few documented patients with distant metastasis, and most of these had metastases at presentation or developed metastases within months to a few years. We add to the short list of metastatic extrapulmonary IMTs a pediatric patient in whom the primary lesion was widespread in the abdomen at presentation and metastatic disease to the lung was diagnosed 9 years after the primary resection. We describe the clinical and pathologic features of this patient and review the characteristics of extrapulmonary IMTs with distant metastasis reported in the literature.

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Thông tin xuất bản

SAGE Publications

Tập 8 Số 2

224-229

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