Pediatric Inflammatory Multisystem Syndrome With Central Nervous System Involvement and Hypocomplementemia Following SARS-COV-2 Infection

Pediatric Infectious Disease Journal - Tập 39 Số 8 - Trang e206-e207 - 2020
Tslil Regev1, Maayan Antebi1, Danny Eytan2,3, Yael Shachor‐Meyouhas4, Anat Ilivitzki2,5,1, Yonatan Butbul Aviel6,2,7, Josef Ben‐Ari3
1Ruth Rappaport Children's Hospital
2Faculty of Medicine, The Technion
3Pediatric Critical Care Unit, Rambam Health Care Campus
4Pediatric Infectious Disease Unit
5Pediatric Radiology Unit
6Department of Pediatrics B
7Pediatric Rheumatology Service, Ruth Rappaport Children's Hospital, Rambam Health Care Campus, Haifa, Israel

Tóm tắt

Pediatric inflammatory multisystem syndromes associated with Severe Acute Respiratory Syndrome Coronavirus 2 are emerging in recent reports. We describe a patient with critical illness consistent with atypical Kawasaki disease with cardiac dysfunction and abdominal involvement presenting weeks after Severe Acute Respiratory Syndrome Coronavirus 2 infection. Our patient showed unique central nervous system involvement with small vessel vasculitis and profound hypocomplementemia, both not previously reported in case descriptions and may hint at possible disease mechanisms.

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