Patients' perspective and usability of innovation technology in a new rehabilitation pathway: An exploratory study in patients with multiple sclerosis

Ghasemi, 2017, Multiple sclerosis: pathogenesis, symptoms, diagnoses and cell-based therapy, Cell J., 19, 1 Katz Sand, 2015, Classification, diagnosis, and differential diagnosis of multiple sclerosis, Curr. Opin. Neurol., 28, 193, 10.1097/WCO.0000000000000206 Milo, 2014, Revised diagnostic criteria of multiple sclerosis, Autoimmun. Rev., 13, 518, 10.1016/j.autrev.2014.01.012 Burridge, 2010, Potential for new technologies in clinical practice, Curr. Opin. Neurol., 23, 671, 10.1097/WCO.0b013e3283402af5 Calabrò, 2016, Robotic gait rehabilitation and substitution devices in neurological disorders: where are we now?, Neurol. Sci., 37, 503, 10.1007/s10072-016-2474-4 Maggio, 2018, Personal computer-based cognitive training in Parkinson's disease: a case study, Psychogeriatrics, 18, 427, 10.1111/psyg.12333 De Luca, R., Leonardi, S., Spadaro, L., et al. Improving cognitive function in patients with stroke: can computerized training be the future?J. Stroke Cerebrovasc. Dis.2018; 27(4):1055-1060. Maresca, 2018, A novel use of virtual reality in the treatment of cognitive and motor deficit in spinal cord injury: a case report, Medicine, 97, e13559, 10.1097/MD.0000000000013559 Calabrò, 2017, Robotic gait training in multiple sclerosis rehabilitation: can virtual reality make the difference? Findings from a randomized controlled trial, J. Neurol. Sci., 377, 25, 10.1016/j.jns.2017.03.047 Maggio, 2019, Virtual reality and cognitive rehabilitation in people with stroke: an overview, J. Neurosci. Nurs., 51, 101, 10.1097/JNN.0000000000000423 Maggio, 2019, Cognitive rehabilitation in patients with traumatic brain injury: a narrative review on the emerging use of virtual reality, J. Clin. Neurosci., 61, 1, 10.1016/j.jocn.2018.12.020 Maggio, 2019, Virtual reality in multiple sclerosis rehabilitation: a review on cognitive and motor outcomes, J. Clin. Neurosci., 65, 106, 10.1016/j.jocn.2019.03.017 Maggio, 2019, The growing use of virtual reality in cognitive rehabilitation: fact, fake or vision? A scoping review, J. Natl. Med. Assoc., 111, 457, 10.1016/j.jnma.2019.01.003 Holden, 2005, Virtual environments for motor rehabilitation: review, Cyberpsychol. Behav., 8, 187, 10.1089/cpb.2005.8.187 Bryanton, 2006, Feasibility, motivation, and selective motor control: virtual reality compared to conventional home exercise in children with cerebral palsy, Cyberpsychol. Behav., 9, 123, 10.1089/cpb.2006.9.123 Novak, 2013, Enhancing patient freedom in rehabilitation robotics using gaze-based intention detection, IEEE Int. Conf. Rehabil. Robot., 2013 Maggio, 2018, Virtual reality-based cognitive rehabilitation in progressive supranuclear palsy, Psychogeriatrics, 18, 427, 10.1111/psyg.12333 Maggio, 2018, What about the role of virtual reality in parkinson disease's cognitive rehabilitation? Preliminary findings from a randomized clinical trial, J. Geriatr. Psychiatry Neurol., 31, 312, 10.1177/0891988718807973 Thompson, 2018, Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria, Lancet Neurol., 17, 162, 10.1016/S1474-4422(17)30470-2 Ng, 2015, Montreal Cognitive Assessment for screening mild cognitive impairment: variations in test performance and scores by education in Singapore, Dement Geriatr. Cogn. Disord., 39, 176, 10.1159/000368827 Meyer-Moock, 2014, Systematic literature review and validity evaluation of the Expanded Disability Status Scale (EDSS) and the multiple sclerosis functional composite (MSFC) in patients with multiple sclerosis, BMC Neurol., 14, 58, 10.1186/1471-2377-14-58 Calabrò, 2020, Innovation technology in neurorehabilitation: introducing a hub and spoke model to avoid patient "migration" in Sicily, J. Health Organ. Manage., 10.1108/JHOM-07-2019-0200 Bertani, 2017, Effects of robot-assisted upper limb rehabilitation in stroke patients: a systematic review with meta-analysis, Neurol. Sci., 38, 1561, 10.1007/s10072-017-2995-5 De Luca, 2016, Tele-health-care in the elderly living in nursing home: the first Sicilian multimodal approach, Aging Clin. Exp. Res., 28, 753, 10.1007/s40520-015-0463-8 Bramanti, 2018, Telemedicine in neurology: where are we going?, Eur. J. Neurol., 25, e6, 10.1111/ene.13477 Bramanti, 2018, Stroke telerehabilitation in sicily: a cost-effective approach to reduce disability?, Innov. Clin. Neurosci., 15, 11 De Cola, 2017, Unmet needs for family caregivers of elderly people with dementia living in Italy: what do we know so far and what should we do next?, Inquiry, 54 Manuli, 2019, Towards improving primary care: considerations on a Sicilian population-based survey, J. Family Med. Prim. Care, 8, 3647, 10.4103/jfmpc.jfmpc_455_19 Maggio, 2019, Effects of robotic neurorehabilitation through lokomat plus virtual reality on cognitive function in patients with traumatic brain injury: a retrospective case-control study, Int. J. Neurosci., 15, 1 Maggio, 2020, Do patients with multiple sclerosis benefit from semi-immersive virtual reality? A randomized clinical trial on cognitive and motor outcomes, Appl. Neuropsychol. Adult, 1 De Luca, 2019, Improving cognitive function after traumatic brain injury: a clinical trial on the potential use of the semi-immersive virtual reality, Behav. Neurol., 2019, 10.1155/2019/9268179 Manuli, 2018, When "cure"; becomes "care"; in robotic neurorehabilitation: the critical role of nurses in a novel Sicilian multidisciplinary approach, Innov. Clin. Neurosci., 15, 11 Langhorne, 2009, Motor recovery after stroke: a systematic review, Lancet Neurol., 8, 741, 10.1016/S1474-4422(09)70150-4 Kwakkel, 2008, Effects of robot-assisted therapy on upper limb recovery after stroke: a systematic review, Neurorehabil. Neural Repair, 22, 111, 10.1177/1545968307305457 Lang, 2015, Dose and timing in neurorehabilitation: prescribing motor therapy after stroke, Curr. Opin. Neurol., 28, 549, 10.1097/WCO.0000000000000256 Calabrò, 2018, Gait rehabilitation following neurological disorders: are robotic devices the future?, Innov. Clin. Neurosci., 15, 11 Russo, 2017, Does body shadow improve the efficacy of virtual reality-based training with BTS NIRVANA?A pilot study, Medicine, 96, e8096, 10.1097/MD.0000000000008096 Maresca, 2019, Moving towards novel multidisciplinary approaches for improving elderly quality of life: the emerging role of telemedicine in Sicily, J. Telemed. Telecare, 25, 318, 10.1177/1357633X17753057 De Cola, 2020, Teleassistance for frail elderly people: a usability and customer satisfaction study, Geriatr. Nurs., 10.1016/j.gerinurse.2020.01.019 Russo, 2018, The role of robotic gait training coupled with virtual reality in boosting the rehabilitative outcomes in patients with multiple sclerosis, Int. J. Rehabil. Res., 41, 166, 10.1097/MRR.0000000000000270 Calabrò, 2017, The role of virtual reality in improving motor performance as revealed by EEG: a randomized clinical trial, J. Neuroeng. Rehabil., 14, 53, 10.1186/s12984-017-0268-4 Resquín, 2016, Hybrid robotic systems for upper limb rehabilitation after stroke: a review, Med. Eng. Phys., 38, 1279, 10.1016/j.medengphy.2016.09.001 Pei, 2017, An evaluation of the design and usability of a novel robotic bilateral arm rehabilitation device for patients with stroke, Front. Neurorobot., 11, 36, 10.3389/fnbot.2017.00036 Grahn, 2000, Motivation as a predictor of changes in quality of life and working ability in multidisciplinary rehabilitation, Disabil. Rehabil., 22, 639, 10.1080/096382800445443 Hughes, 2011, Stroke participants’ perceptions of robotic and electrical stimulation therapy: a new approach, Disabil. Rehabil. Assist. Technol., 6, 130, 10.3109/17483107.2010.509882 Huang, 2017, Robot-assisted post-stroke motion rehabilitation in upper extremities: a survey, Int. J. Disabil. Hum. Dev., 16, 10.1515/ijdhd-2016-0035 Kim, 2010, Robot-assisted modifications of gait in healthy individuals, Exp. Brain Res., 202, 809, 10.1007/s00221-010-2187-5 Peurala, 2009, Effects of intensive therapy using gait trainer or floor walking exercises early after stroke, J. Rehabil. Med., 41, 166, 10.2340/16501977-0304 Duncan, 2011, LEAPS investigative team. Body-weight-supported treadmill rehabilitation after stroke, N. Engl. J. Med., 26, 2026, 10.1056/NEJMoa1010790 Morone, 2011, Who may benefit from robotic-assisted gait training? A randomized clinical trial in patients with subacute stroke, Neurorehabil. Neural Repair, 25, 636, 10.1177/1545968311401034 Pohl, 2007, Repetitive locomotor training and physiotherapy improve walking and basic activities of daily living after stroke: a single-blind, randomized multicentre trial (DEutsche GAngtrainerStudie, DEGAS), Clin. Rehabil., 2, 17, 10.1177/0269215506071281 Hidler, 2009, Multicenter randomized clinical trial evaluating the effectiveness of the Lokomat in subacute stroke, Neurorehabil. Neural Repair, 23, 5, 10.1177/1545968308326632 Calabrò, 2018, Shaping neuroplasticity by using powered exoskeletons in patients with stroke: a randomized clinical trial, J. Neuroeng. Rehabil., 15, 35, 10.1186/s12984-018-0377-8 Calabrò, 2020, Improving motor performance in Parkinson's disease: a preliminary study on the promising use of the computer assisted virtual reality environment (CAREN), Neurol. Sci., 41, 933, 10.1007/s10072-019-04194-7 Maggio, 2020, Effects of domotics on cognitive, social and personal functioning in patients with chronic stroke: a pilot study, Disabil. Health J., 13, 10.1016/j.dhjo.2019.100838 Iosa, 2011, Driving electromechanically assisted Gait Trainer for people with stroke, J. Rehabil. Res. Dev., 48, 135, 10.1682/JRRD.2010.04.0069 Morone, 2012, Who may have durable benefit from robotic gait training? A 2-year follow-up randomized controlled trial in patients with subacute stroke, Stroke, 43, 1140, 10.1161/STROKEAHA.111.638148 Ng, 2008, A pilot study of randomized clinical controlled trial of gait training in subacute stroke patients with partial body-weight support electromechanical gait trainer and functional electrical stimulation: six-month follow-up, Stroke, 39, 154, 10.1161/STROKEAHA.107.495705 Swinnen, 2012, Treadmill training in multiple sclerosis: can body weight support or robot assistance provide added value? A systematic review, Mult. Scler. Int., 2012 Pompa, 2017, Does robot-assisted gait training improve ambulation in highly disabled multiple sclerosis people? A pilot randomized control trial, Mult. Scler., 23, 696, 10.1177/1352458516663033 Benedetti, 2009, Treadmill exercise in early multiple sclerosis: a case series study, Eur. J. Phys. Rehabil. Med., 45, 53 Giesser, 2007, Locomotor training using body weight support on a treadmill improves mobility in persons with multiple sclerosis: a pilot study, Mult. Scler., 13, 224, 10.1177/1352458506070663 Pilutti, 2011, Effects of 12 weeks of supported treadmill training on functional ability and quality of life in progressive multiple sclerosis: a pilot study, Arch. Phys. Med. Rehabil., 92, 31, 10.1016/j.apmr.2010.08.027 Lo, 2008, Improving gait in multiple sclerosis using robot-assisted, body weight supported treadmill training, Neurorehabil. Neural Repair, 22, 661, 10.1177/1545968308318473 Beer, 2008, Robot-assisted gait training in multiple sclerosis: a pilot randomized trial, Mult. Scler., 14, 231, 10.1177/1352458507082358 Vaney, 2012, Robotic-assisted step training (lokomat) not superior to equal intensity of over-ground rehabilitation in patients with multiple sclerosis, Neurorehabil. Neural Repair, 26, 212, 10.1177/1545968311425923 Schwartz, 2012, Robot-assisted gait training in multiple sclerosis patients: a randomized trial, Mult. Scler., 18, 881, 10.1177/1352458511431075 Straudi, 2013, Does robot-assisted gait training ameliorate gait abnormalities in multiple sclerosis? A pilot randomized-control trial, NeuroRehabilitation, 33, 555, 10.3233/NRE-130990 Gandolfi, 2014, Robot-assisted vs. sensory integration training in treating gait and balance dysfunctions in patients with multiple sclerosis: a randomized controlled trial, Front. Hum. Neurosci., 8, 318, 10.3389/fnhum.2014.00318 Straudi, 2016, The effects of robot-assisted gait training in progressive multiple sclerosis: a randomized controlled trial, Mult. Scler., 22, 373, 10.1177/1352458515620933 Ruiz, 2013, Combination of robot-assisted and conventional body-weight-supported treadmill training improves gait in persons with multiple sclerosis: a pilot study, J. Neurol. Phys. Ther., 37, 187, 10.1097/NPT.0000000000000018 Thoma, 2018, Experiences of nurse case managers within a central discharge planning role of collaboration between physicians, patients and other healthcare professionals: a sociocultural qualitative study, J. Clin. Nurs., 27, 1198, 10.1111/jocn.14166