Patients over 65 years are assigned lower ECOG PS scores than younger patients, although objectively measured physical activity is no different

Ando, 2001, Prognostic value of performance status assessed by patients themselves, nurses, oncologists in advanced non-small cell lung cancer, Br J Cancer, 85, 1634, 10.1054/bjoc.2001.2162 Oken, 1982, Toxicity and response criteria and the Eastern Cooperative Oncology Group, Am J Clin Oncol, 5, 649, 10.1097/00000421-198212000-00014 Chen, 2003, Can older patients tolerate chemotherapy? A prospective pilot study, Cancer, 97, 1107, 10.1002/cncr.11110 Troiano, 2008, Physical activity in the United States measured by accelerometer, Med Sci Sports Exerc, 40, 181, 10.1249/mss.0b013e31815a51b3 Extermann, 1988, Comorbidity and functional status are independent in older cancer patients, J Clin Oncol, 16, 1582, 10.1200/JCO.1998.16.4.1582 Repetto, 2002, Comprehensive geriatric assessment adds information to Eastern Cooperative Oncology Group performance status in elderly cancer patients: an Italian Group for Geriatric Oncology Study, J Clin Oncol, 20, 494, 10.1200/JCO.2002.20.2.494 Balducci, 2010, Assessment and treatment of elderly patients with cancer, Surg Oncol, 19, 117, 10.1016/j.suronc.2009.11.008 Deans, 2007, Clinical prognostic scoring system to aid decision-making in gastro-oesophageal cancer, Br J Surg, 95, 1501, 10.1002/bjs.5849 Albain, 1991, Survival determinants in extensive-stage non-small cell lung cancer: the south west Oncology Group experience, J Clin Oncol, 9, 1618, 10.1200/JCO.1991.9.9.1618 Motzer, 1999, Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma, J Clin Oncol, 17, 2530, 10.1200/JCO.1999.17.8.2530 Sengelov, 2000, Predictive factors of response to cisplatin-based chemotherapy and the relation of response to survival in patients with metastatic urothelial cancer, Cancer Chemother Pharmacol, 46, 357, 10.1007/s002800000176 Jordhoy, 2001, Quality-of-life in advanced cancer patients: the impact of sociodemographic and medical characteristics, Br J Cancer, 85, 1478, 10.1054/bjoc.2001.2116 Schaafsma, 1994, The Karnofsky performance status scale re-examined: a cross validation with the EORTC-C30, Qual Life Res, 3, 413, 10.1007/BF00435393 Brown, 2004, The correlation between fatigue, physical function, the systemic inflammatory response, and psychological distress in patients with advanced cancer, Cancer, 103, 377, 10.1002/cncr.20777 Scott, 2002, The systemic inflammatory response, weight loss, performance status and survival in patients with inoperable non-small cell lung cancer, Br J Cancer, 87, 264, 10.1038/sj.bjc.6600466 Akechi, 2004, Major depression, adjustment disorders, and post-traumatic stress disorder in terminally ill cancer patients: associated and predictive factors, J Clin Oncol, 22, 1957, 10.1200/JCO.2004.08.149 LLoyd-Williams, 2004, A prospective study to determine the association between physical symptoms and depression in patients with advanced cancer, Palliat Med, 18, 558, 10.1191/0269216304pm923oa Dimeo, 2004, Physical performance, depression, immune status and fatigue in patients with hematological malignancies, Ann Oncol, 15, 1237, 10.1093/annonc/mdh314 Blagden, 2003, Performance status score: do patients and their oncologists agree?, Br J Cancer, 89, 1022, 10.1038/sj.bjc.6601231 Loprinzi, 1994, Prospective evaluation of prognostic variables from patient-completed questionnaires. North Cancer Treatment Group, J Clin Oncol, 12, 601, 10.1200/JCO.1994.12.3.601 Lilenbaum, 2008, Prevalence of poor performance status in lung cancer patients, J Thorac Oncol, 3, 125, 10.1097/JTO.0b013e3181622c17 Buccheri, 1996, Karnofsky and ECOG performance status scoring in lung cancer: a prospective, longitudinal study of 536 patients from a single institution, Eur J Cancer, 7, 1135, 10.1016/0959-8049(95)00664-8 Extermann, 2012, Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score, Cancer, 118, 3377, 10.1002/cncr.26646 Sallis, 2000, Assessment of physical activity by self-report: status, limitations, and future directions, Res Q Exerc Sport, 71, S1, 10.1080/02701367.2000.11082780 Craig, 2003, International physical activity questionnaire: 12-country reliability and validity, Med Sci Sports Exerc, 35, 1381, 10.1249/01.MSS.0000078924.61453.FB Rowlands, 2004, Validation of the RT3 triaxial accelerometer for the assessment of physical activity, Med Sci Sports Exerc, 36, 518, 10.1249/01.MSS.0000117158.14542.E7 Pitta, 2005, Characteristics of physical activities in daily life in chronic obstructive pulmonary disease, Am J Respir Crit Care Med, 171, 972, 10.1164/rccm.200407-855OC Charlson, 1987, A new method of classifying prognostic comorbidity in longitudinal studies: development and validation, J Chronic Dis, 40, 373, 10.1016/0021-9681(87)90171-8 Sumukadas, 2008, Using the RT3 accelerometer to measure everyday activity in functionally impaired older people, Aging Clin Exp Res, 20, 15, 10.1007/BF03324742 Hale, 2008, Measuring free-living physical activity in adults with or without neurologic dysfunction with a triaxial accelerometer, Arch Phys Med Rehabil, 89, 1765, 10.1016/j.apmr.2008.02.027