Pathogenic protease expression in murine OA is critically dependent upon mechanical joint loading
Tài liệu tham khảo
Glasson SS, et al: Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature. 2005, 434 (7033): 644-8. 10.1038/nature03369.
Little CB, et al: Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. Arthritis Rheum. 2009, 60 (12): 3723-33. 10.1002/art.25002.