Passive smoking and lung cancer in nonsmoking women.

American journal of public health - Tập 82 Số 11 - Trang 1525-1530 - 1992
Ross C. Brownson1, Matthew R. Bonner, E T Hock, Timothy S. Loy
1Division of Chronic Disease Prevention and Health Promotion, Missouri Department of Health, Columbia 65203.

Tóm tắt

OBJECTIVES. The causes of lung cancer among nonsmokers are not clearly understood. To further evaluate the relation between passive smoke exposure and lung cancer in nonsmoking women, we conducted a population-based, case-control study. METHODS. Case patients (n = 618), identified through the Missouri Cancer Registry for the period 1986 through 1991, included 432 lifetime nonsmokers and 186 ex-smokers who had stopped at least 15 years before diagnosis or who had smoked for less than 1 pack-year. Control subjects (n = 1402) were selected from driver's license and Medicare files. RESULTS. No increased risk of lung cancer was associated with childhood passive smoke exposure. Adulthood analyses showed an increased lung cancer risk for lifetime nonsmokers with exposure of more than 40 pack-years from all household members (odds ratio [OR] = 1.3; 95% confidence interval [CI] = 1.0, 1.8) or from spouses only (OR = 1.3; 95% CI = 1.0, 1.7). When the time-weighted product of pack-years and average hours exposed per day was considered, a 30% excess risk was shown at the highest quartile of exposure among lifetime nonsmokers. CONCLUSIONS. Ours and other recent studies suggest a small but consistent increased risk of lung cancer from passive smoking. Comprehensive actions to limit smoking in public places and worksites are well-advised.

Từ khóa


Tài liệu tham khảo

10.1002/1097-0142(19840301)53:5<1214::AID-CNCR2820530532>3.0.CO;2-8

10.1093/jnci/76.4.597

10.1002/1097-0142(19881201)62:11<2397::AID-CNCR2820621125>3.0.CO;2-5

Schoenberg JB, Wilcox HB, Mason TJ, Bill J, Stemhagen A. Variation in smokingrelated Iung cancer risk among New Jersey women. Am J EpidemioL 1989;130:688-695.

Dalager NA, 1986, Cancer Res., 46, 4804

Garfinkel L. Time trends in Iung cancer mortality among nonsmokers and a note on passive smoking.JNatICancerInst. 1981; 66:1061-1066.

10.1016/S0140-6736(83)90680-3

10.1016/S0140-6736(83)92549-7

HirayamaT. Cancermortalityinnonsmoking women with smoking husbands based on a large-scale cohort study in Japan. Prev MeL 1984;13:680-690.

Garfinkel L, Auerbach 0, Joubert L. Involuntary smoking and Iung cancer: a casecontrol study. INatiCancer Inst. 1985;75: 463-469.

Wu AH, Henderson BE, Pike MC, Yu MC. Smoking and other risk factors for lung cancer in women. JNad CancerInst. 1985;74:747-751.

Akiba S, 1986, CancerRes., 46, 4804

Brownson RC, Reif JS, Keefe TJ, Ferguson SW, Pritzl JA. Risk factors for adenocarcinoma of the Iung. Am J EpdemioL 1987;125:25-34.

10.1002/ijc.2910400505

Hole DJ, Giflis CR, Chopra C, Hawtre VM. Passive smoking and cardoespiratory health in a general population in the west of Scoland. Br Med J. 1989-299:423-427.

Humble CG, Samet JM, Pathak DR. Marriage to a smoker and Iung cancer risk.AAm JPublic Healt 1987;77:598-602.

10.1038/bjc.1987.264

Pershagen G, Zdenek H, Svensson C. Passive smoking and Iung cancer in Swedish women. Am J EpidemidoL 1987;125:17-24.

Kalandidi A, Katsouyanni K, Voropoulou N, etal. Passive smoking and diet in the etiology of Iung cancer among non-smokers. Cancer Causes ControL 1990;1:15-21.

Fontham ETH, 1991, Cancer EpidemiolBiomarkersPrev., 1, 35

National Research Council, Board on Environmental Studies and Toxicology, Committee on Passive Smoking. Environmental Tobacco Smoke: Measuring Exposures and Assessing Health Effects. Washington, DC: National Academy Press; 1986.

National Institute for Occupational Safety and Health. Environental Tobacco Smnke in the Wolmace- Ig Cancer and Other Health Effects. Cincinnati, Ohio: National Institute for Occupational Safety and Health; 1991. DHHS publication NIOSH 91-108. Current Intelligence Bulletin 54.

Chan WC, Fung SC. Lung cancer in nonsmokers in Hong Kong. In: Grundmann E, Clemmesen J, Muir CS, eds. Cancer Campair VoL 6: Geogniphical Pathology i Cancer Epidemiology. New York, NY: Gustav Fischer Verlag; 1982:199-202.

BuffierPA, Pickle LW, Mason TJ, Contant C. The causes of Iung cancer in Texas. In: Mizell M, Correa P, eds. Lung Cancer: Causes and Prevention. New York, NY: Verlag-Chemie International, Inc; 1984.

10.1038/bjc.1986.157

Janerich DT, Thompson WD, Varela LR, etal. Lung cancer and exposure to tobacco smoke in the household. N EngI J Med. 1990;323:632-636.

10.1038/bjc.1990.421

Brownson RC, Davis JR, Chang JC, DiLorenzo TM, Keefe TJ, Bagby JR Jr. A study of the accuracy of cancer risk factor information reported to a central registry compared with that obtained by interview. Am J EpidemioL 1989;129:616-624.

World Health Organization. The World Health Organization histologic typing of lung tumors, 2nd ed. Am J Cin PathoL 1982;77:123-136.

Koss LG. Diagnoric Cytology and its Histopathologi Bases. 3rd ed. Philadelphia, Pa: JB Lippincott Co; 1979.

Hatten J, 1980, Health Care Finance Rev., 2, 53

Wynder EL, Goodman MT, Hoffmann K. Lung cancer etiology: challenges of the future. Carr&ngenesis. 1985;8:39-61.

Breslow NE, Day NE. Statistical Methods in Cancer Research Volume I-The Analysis of Case-Control Studies. Lyon, France: International Agency of Research on Cancer; 1980. [ARC publication 32.

10.2307/2282717

10.1093/oxfordjournals.epirev.a036258

10.2105/AJPH.73.4.401

Cummings KM, Markeilo SJ, Mahoney MC, Marshall JR. Measurement of lifetime exposure to passive smoke. Am J EpidemioL 1989;130:122-132.

10.1001/jama.1989.03420010059033

US Dept of Health and Human Services. The Health Benefis of Smokdng Cessation. Rockville, Md: Centers for Disease Control; 1990. DHHS publication CDC 90-8416.

Pron GE, Burch JD, Howe GR, Miler AB. The reliability of passive smoking hisories reported in a case-control study of Iung cancer. Am J EpiderioL 1988; 127:267-273.

Coultas DB, Peake GT, Samet JM. Questionnaire assessment of lifetime and recent exposure to environmental tobacco smoke. AmJEpidemioL 1989;130:338-347.

Lerchen ML, Samet JM. An assessment of the validity of questionnaire responses provided by a sulviving spouse. Am J EpidemioL 1986;123:481-489.

Rigotti NA, Pashos CL. No-smoking laws in the United States: an analysis of state and city actions to limit smoking in public places and workplaces. JAMA4. 1991;266: 3162-3167.

Thông tin
Thông tin xuất bản

American journal of public health

Tập 82 Số 11

1525-1530

Thông tin tác giả