Parasite Load Induces Progressive Spleen Architecture Breakage and Impairs Cytokine mRNA Expression in Leishmania infantum-Naturally Infected Dogs

PLoS ONE - Tập 10 Số 4 - Trang e0123009
Amanda dos Santos Cavalcanti1, Marcelo Ribeiro-Alves2, Luiza de Oliveira Ramos Pereira3, Gustavo Leandro da Cruz Mestre4, Anna Beatriz Robottom Ferreira5, Fernanda N. Morgado1, Mariana Côrtes Boité1, Elisa Cupolillo1, Milton Ozório Moraes5, Renato Porrozzi1
1Laboratório de Pesquisas em Leishmaniose, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brasil
2Laboratório de Pesquisa Clínica em DST-AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz, Rio de Janeiro, Brasil.
3Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, Brasil.
4Centro de Controle de Zoonoses, Secretaria Municipal de Saúde, Cuiabá, Brasil
5Laboratório de Hanseníase, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, Brasil.

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