Paralog dependency indirectly affects the robustness of human cells
Tóm tắt
Từ khóa
Tài liệu tham khảo
DandageR(2019)rraadd88/rohan v0.1.0
DepMapB(2018)DepMap Achilles 18Q3 public
JonesE OliphantT PetersonPet al(2001)SciPy: open source scientific tools for Python
Karczewski KJ, 2019, Variation across 141,456 human exomes and genomes reveals the spectrum of loss‐of‐function intolerance across human protein‐coding genes, bioRxiv, 531210
Pedregosa F, 2011, Scikit‐learn: machine learning in Python, J Mach Learn Res, 12, 2825
RubinsteynA NathansonT KodyshJ O'DonnellT AhujaA HammerbacherJ Arman AksoyB Pedersen‐BioinformaticsB GrouèsV HodesI(2017)hammerlab/pyensembl: Version 1.1.0
WaskomM BotvinnikO O'KaneD HobsonP OstblomJ LukauskasS GemperlineDC AugspurgerT HalchenkoY ColeJBet al(2018)mwaskom/seaborn: v0.9.0 (July 2018)
BioGRID PPI dataset(2018)BioGRID version 3.5.167(https://downloads.thebiogrid.org/Download/BioGRID/Release-Archive/BIOGRID43.5.167/BIOGRID-ORGANISM-3.5.167) [DATASET]
Human proteome sequences all annotated peptides(2018)Ensembl release 95(ftp://ftp.ensembl.org/pub/release-95/fasta/homo_sapiens/pep/Homo_sapiens.GRCh38.pep.all.fa.gz) [DATASET]
IntAct PPI dataset(2019)IntAct version 2019‐03‐22(ftp://ftp.ebi.ac.uk/pub/databases/intact/2019-03-22/) [DATASET]
Ohnolog families and ohnolog pairs for human (Homo sapiens) for 2R WGD(2018)Ohnolog version 2(http://ohnologs.curie.fr/cgi10bin/BrowsePage.cgi?org=hsapiens) [DATASET]