Parabrachial nucleus neuron circuits that control feeding behavior and energy balance

Obesity Medicine - Tập 42 - Trang 100509 - 2023
Zihao Zhao1,2, Yufan Chen1,2, Yunxin Xuan2, Guoxiang Zhou2, Weiwei Qiu1,2,3
1Edinburgh Medical School, Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Old College, South Bridge, Edinburgh, EH8 9YL, UK
2Zhejiang University-University of Edinburgh Institute, International Campus, Zhejiang University, 718 East Haizhou Rd, Haining, 314400, China
3Department of Endocrinology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Rd, Hangzhou, 310058, China

Tài liệu tham khảo

Adams, 2018, Liraglutide modulates appetite and body weight through glucagon-like peptide 1 receptor-expressing glutamatergic neurons, Diabetes, 67, 1538, 10.2337/db17-1385 Alhadeff, 2014, Glucagon-like Peptide-1 receptor signaling in the lateral parabrachial nucleus contributes to the control of food intake and motivation to feed, Neuropsychopharmacology, 39, 2233, 10.1038/npp.2014.74 Alhadeff, 2014, Leptin receptor signaling in the lateral parabrachial nucleus contributes to the control of food intake, Am. J. Physiol. Regul. Integr. Comp. Physiol., 307, R1338, 10.1152/ajpregu.00329.2014 Alhadeff, 2017, Excitatory hindbrain-forebrain communication is required for cisplatin-induced anorexia and weight loss, J. Neurosci. : Off. J. Soc. Neurosci., 37, 362, 10.1523/JNEUROSCI.2714-16.2016 Allen, 2023, A parabrachial-to-amygdala circuit that determines hemispheric lateralization of somatosensory processing, Biol. Psychiatr., 93, 370, 10.1016/j.biopsych.2022.09.010 American Psychiatric Association, 2013 Bai, 2019, Genetic identification of vagal sensory neurons that control feeding, Cell, 179, 10.1016/j.cell.2019.10.031 Becskei, 2007, Lesion of the lateral parabrachial nucleus attenuates the anorectic effect of peripheral amylin and CCK, Brain Res., 1162, 76, 10.1016/j.brainres.2007.06.016 Berrios, 2021, Food cue regulation of AGRP hunger neurons guides learning, Nature, 595, 695, 10.1038/s41586-021-03729-3 Bowen, 2020, Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons, Elife, 9, 10.7554/eLife.59799 Broberger, 1998, Hypocretin/Orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: relationship to the neuropeptide Y and agouti gene-related protein systems, J. Comp. Neurol., 402, 460, 10.1002/(SICI)1096-9861(19981228)402:4<460::AID-CNE3>3.0.CO;2-S Broberger, 1998, The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice, Proc. Natl. Acad. Sci. U S A, 95, 15043, 10.1073/pnas.95.25.15043 Campos, 2016, Parabrachial CGRP neurons control meal termination, Cell Metabol., 23, 811, 10.1016/j.cmet.2016.04.006 Campos, 2017, Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus, Nat. Neurosci., 20, 934, 10.1038/nn.4574 Campos, 2018, Encoding of danger by parabrachial CGRP neurons, Nature, 555, 617, 10.1038/nature25511 Carter, 2013, Genetic identification of a neural circuit that suppresses appetite, Nature, 503, 111, 10.1038/nature12596 Chen, 2018, Parabrachial CGRP neurons establish and sustain aversive taste memories, Neuron, 100, 891, 10.1016/j.neuron.2018.09.032 Cheng, 2020, Calcitonin receptor neurons in the mouse nucleus tractus solitarius control energy balance via the non-aversive suppression of feeding, Cell Metabol., 31, 301, 10.1016/j.cmet.2019.12.012 Cheng, 2022, Hindbrain circuits in the control of eating behaviour and energy balance, Nat. Metab., 4, 826, 10.1038/s42255-022-00606-9 Chou, 2022, CGRP-dependent sensitization of PKC-delta positive neurons in central amygdala mediates chronic migraine, J. Headache Pain, 23, 157, 10.1186/s10194-022-01531-8 Coll, 2020, GDF15 mediates the effects of metformin on body weight and energy balance, Nature, 578, 444, 10.1038/s41586-019-1911-y Douglass, 2017, Central amygdala circuits modulate food consumption through a positive-valence mechanism, Nat. Neurosci., 20, 1384, 10.1038/nn.4623 Elmquist, 1997, Leptin activates neurons in ventrobasal hypothalamus and brainstem, Endocrinology, 138, 839, 10.1210/endo.138.2.5033 Emmerson, 2017, The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL, Nat. Med., 23, 1215, 10.1038/nm.4393 Essner, 2017, AgRP neurons can increase food intake during conditions of appetite suppression and inhibit anorexigenic parabrachial neurons, J. Neurosci. : Off. J. Soc. Neurosci., 37, 8678, 10.1523/JNEUROSCI.0798-17.2017 Flak, 2014, Leptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balance, Nat. Neurosci., 17, 1744, 10.1038/nn.3861 Fu, 2019, SatB2-Expressing neurons in the parabrachial nucleus encode sweet taste, Cell Rep., 27, 1650, 10.1016/j.celrep.2019.04.040 Garfield, 2015, A neural basis for melanocortin-4 receptor-regulated appetite, Nat. Neurosci., 18, 863, 10.1038/nn.4011 Grill, 2002, Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake, Endocrinology, 143, 239, 10.1210/endo.143.1.8589 Hahn, 1998, Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons, Nat. Neurosci., 1, 271, 10.1038/1082 Han, 2015, Elucidating an affective pain circuit that creates a threat memory, Cell, 162, 363, 10.1016/j.cell.2015.05.057 Han, 2018, A neural circuit for gut-induced reward, Cell, 175, 665, 10.1016/j.cell.2018.08.049 Hardaway, 2019, Central amygdala prepronociceptin-expressing neurons mediate palatable food consumption and reward, Neuron, 102, 1037, 10.1016/j.neuron.2019.03.037 Horn, 2009, Chemotherapy-induced kaolin intake is increased by lesion of the lateral parabrachial nucleus of the rat, Am. J. Physiol. Regul. Integr. Comp. Physiol., 297, R1375, 10.1152/ajpregu.00284.2009 Hosoi, 2002, Brain stem is a direct target for leptin's action in the central nervous system, Endocrinology, 143, 3498, 10.1210/en.2002-220077 Hsu, 2017, Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15, Nature, 550, 255, 10.1038/nature24042 Huang, 2021, Efferent projections of CGRP/Calca-expressing parabrachial neurons in mice, J. Comp. Neurol., 529, 2911, 10.1002/cne.25136 Jarvie, 2021, Satb2 neurons in the parabrachial nucleus mediate taste perception, Nat. Commun., 12, 224, 10.1038/s41467-020-20100-8 Johnen, 2007, Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1, Nat. Med., 13, 1333, 10.1038/nm1677 Kang, 2022, A central alarm system that gates multi-sensory innate threat cues to the amygdala, Cell Rep., 40, 10.1016/j.celrep.2022.111222 Kim, 2020, A neural circuit mechanism for mechanosensory feedback control of ingestion, Nature, 580, 376, 10.1038/s41586-020-2167-2 Le May, 2021, Functional and neurochemical identification of ghrelin receptor (GHSR)-Expressing cells of the lateral parabrachial nucleus in mice, Front. Neurosci., 15, 10.3389/fnins.2021.633018 Leinninger, 2009, Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding, Cell Metabol., 10, 89, 10.1016/j.cmet.2009.06.011 Li, 1994, Reversal of dexfenfluramine-induced anorexia and c-Fos/c-Jun expression by lesion in the lateral parabrachial nucleus, Brain Res., 640, 255, 10.1016/0006-8993(94)91881-3 Linders, 2022, Stress-driven potentiation of lateral hypothalamic synapses onto ventral tegmental area dopamine neurons causes increased consumption of palatable food, Nat. Commun., 13, 6898, 10.1038/s41467-022-34625-7 Liu, 2023, An iterative neural processing sequence orchestrates feeding, Neuron, 111, 1651, 10.1016/j.neuron.2023.02.025 Mercer, 1998, Localization of leptin receptor (Ob-R) messenger ribonucleic acid in the rodent hindbrain, Endocrinology, 139, 29, 10.1210/endo.139.1.5685 Merchenthaler, 1999, Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system, J. Comp. Neurol., 403, 261, 10.1002/(SICI)1096-9861(19990111)403:2<261::AID-CNE8>3.0.CO;2-5 Mishra, 2019, Parabrachial interleukin-6 reduces body weight and food intake and increases thermogenesis to regulate energy metabolism, Cell Rep., 26, 3011, 10.1016/j.celrep.2019.02.044 Morton, 2006, Central nervous system control of food intake and body weight, Nature, 443, 289, 10.1038/nature05026 Mullican, 2017, GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates, Nat. Med., 23, 1150, 10.1038/nm.4392 Nagashima, 2022, Parabrachial-to-parasubthalamic nucleus pathway mediates fear-induced suppression of feeding in male mice, Nat. Commun., 13, 7913, 10.1038/s41467-022-35634-2 Norris, 2021, Parabrachial opioidergic projections to preoptic hypothalamus mediate behavioral and physiological thermal defenses, Elife, 10, 10.7554/eLife.60779 Osterhout, 2022, A preoptic neuronal population controls fever and appetite during sickness, Nature, 606, 937, 10.1038/s41586-022-04793-z Park, 2022, Leptin-inhibited neurons in the lateral parabrachial nucleus do not alter food intake or glucose balance, Anim. Cell Syst., 26, 92, 10.1080/19768354.2022.2084159 Pauli, 2022, Molecular and anatomical characterization of parabrachial neurons and their axonal projections, Elife, 11 Phua, 2021, A distinct parabrachial-to-lateral hypothalamus circuit for motivational suppression of feeding by nociception, Sci. Adv., 7, 10.1126/sciadv.abe4323 Qian, 2022, A temperature-regulated circuit for feeding behavior, Nat. Commun., 13, 4229, 10.1038/s41467-022-31917-w Richard, 2014, GLP-1 receptor stimulation of the lateral parabrachial nucleus reduces food intake: neuroanatomical, electrophysiological, and behavioral evidence, Endocrinology, 155, 4356, 10.1210/en.2014-1248 Roman, 2016, Genetically and functionally defined NTS to PBN brain circuits mediating anorexia, Nat. Commun., 7, 10.1038/ncomms11905 Roman, 2017, A tale of two circuits: CCK(NTS) neuron stimulation controls appetite and induces opposing motivational states by projections to distinct brain regions, Neuroscience, 358, 316, 10.1016/j.neuroscience.2017.06.049 Ryan, 2017, Oxytocin-receptor-expressing neurons in the parabrachial nucleus regulate fluid intake, Nat. Neurosci., 20, 1722, 10.1038/s41593-017-0014-z Sabatini, 2021, GFRAL-expressing neurons suppress food intake via aversive pathways, Proc. Natl. Acad. Sci. U S A, 118, 10.1073/pnas.2021357118 Shah, 2014, MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus, Proc. Natl. Acad. Sci. U S A, 111, 13193, 10.1073/pnas.1407843111 Siemian, 2021, Hypothalamic control of interoceptive hunger, Curr. Biol., 31, 3797, 10.1016/j.cub.2021.06.048 Siemian, 2021, Lateral hypothalamic LEPR neurons drive appetitive but not consummatory behaviors, Cell Rep., 36, 10.1016/j.celrep.2021.109615 Singh, 2022, Neuroanatomical organization and functional roles of PVN MC4R pathways in physiological and behavioral regulations, Mol. Metabol., 55, 10.1016/j.molmet.2021.101401 Treasure, 2020, Eating disorders, Lancet, 395, 899, 10.1016/S0140-6736(20)30059-3 Wu, 2009, Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation, Cell, 137, 1225, 10.1016/j.cell.2009.04.022 Wu, 2012, Deciphering a neuronal circuit that mediates appetite, Nature, 483, 594, 10.1038/nature10899 Yang, 2017, GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand, Nat. Med., 23, 1158, 10.1038/nm.4394 Yang, 2020, Parabrachial neuron types categorically encode thermoregulation variables during heat defense, Sci. Adv., 6, 10.1126/sciadv.abb9414 Yang, 2021, An mPOA-ARC(AgRP) pathway modulates cold-evoked eating behavior, Cell Rep., 36, 10.1016/j.celrep.2021.109502 Yang, 2021, Locus coeruleus anchors a trisynaptic circuit controlling fear-induced suppression of feeding, Neuron, 109, 823, 10.1016/j.neuron.2020.12.023 Zhang, 2020, Ghrelin in the lateral parabrachial nucleus influences the excitability of glucosensing neurons, increases food intake and body weight, Endocr. Connect., 9, 1168, 10.1530/EC-20-0285