Pancreatic Cancer: Yesterday, Today and Tomorrow

Morgagni G . De Sedibus, et Causis Morborum per Anatomen Indagatis Libri Quinque. Venetiis, Typog Remondiniana (1761).

Da Costa J . On the Morbid Anatomy and Symptoms of Cancer of the Pancreas. JB Lippincott & Company, Philadelphia, PA, USA (1858).

Codivilla A . Rendiconto statistico della sezione chirurgica dell’ospedale di Imola. Imola Italy (1898).

10.1056/NEJM189912281412601

Kausch W . Das carcinom der papilla duodeni und seine radikale entfernung. Beitr. Klin. Chir.78, 439–486 (1912).

Hirschel G . Die resektion des duodenums mit der papille wegen karzinoms. Munch. Med. Wochenschr.61, 1728–1729 (1914).

10.1097/00000658-193510000-00023

Whipple AO . Observations on radical surgery for lesions of the pancreas. Surg. Gynecol. Obstet.82, 623–631 (1946).

Whipple AO . A reminiscence: pancreaticduodenectomy. Rev. Surg.20, 221–225 (1963).

Brunschwig A . Resection of the head of pancreas and duodenum for carcinoma – pancreatoduodenectomy. Surg. Gynecol. Obstet.65, 681–684 (1937).

10.3109/00365521.2013.847116

10.1002/bjs.5982

10.1002/bjs.9420

10.1158/0008-5472.CAN-14-0155

10.1093/annonc/mdv001

10.3109/02841861003782017

10.3748/wjg.v20.i32.11182

10.1159/000323933

10.1002/mc.20778

10.1016/j.bpg.2010.02.007

10.1093/annonc/mdr120

10.1002/ijc.24936

10.1001/jama.1995.03520440059037

10.1159/000264676

10.1016/j.gtc.2007.08.012

10.1038/nrc3420

10.1038/nature09515

AJCC Cancer Staging Manual (7th Edition) . Springer, NY, USA (2010).

10.1002/cncr.10492

10.1097/MPA.0000000000000368

10.3322/caac.21254

10.1136/gutjnl-2012-303108

10.1016/j.jss.2014.06.046

10.1016/j.ejso.2006.10.004

10.1093/annonc/mdp332

10.1016/j.ejrad.2012.09.012

10.1148/radiol.2211001157

10.1148/radiol.14130778

10.1111/j.1443-1661.2011.01113.x

10.1111/hpb.12074

10.1016/j.canlet.2013.08.008

10.1021/acs.molpharmaceut.5b00626

10.1148/radiol.13131184

10.20524/aog.2016.0016

10.1245/s10434-014-3493-0

10.1016/j.ejon.2005.09.006

10.1002/jso.23304

10.1002/jso.23862

10.1056/NEJMoa0903230

10.1136/gutjnl-2014-308762

10.1016/j.jamcollsurg.2015.03.058

10.1002/bjs.9553

10.1097/SLA.0000000000000806

10.1111/hpb.12186

10.1002/bjs.8784

10.1007/s11605-012-1898-2

National Comprehensive Cancer Network . Clinical Practice Guidelines in Oncology. Pancreatic Adenocarcinoma. Version 2 (2015). www.nccn.org/professionals/physician_gls/f_guidelines.asp.

10.4251/wjgo.v7.i10.241

10.1016/j.surg.2014.02.001

Moore GE , SakoY, ThomasLB. Radical pancreatoduodenectomy with resection and reanastomosis of the superior mesenteric vein. Surgery30(3), 550–553 (1951).

10.1001/archsurg.1963.01310160071012

Fortner JG . Regional resection of cancer of the pancreas: a new surgical approach. Surgery73(2), 307–320 (1973).

10.1007/s00268-012-1461-z

10.4174/jkss.2013.84.6.346

10.1016/j.jvs.2015.01.061

10.1016/j.surg.2014.12.002

10.1001/archsurg.2011.688

10.1097/SLA.0b013e31823ac299

10.1016/j.surg.2014.06.016

10.1007/s11605-015-2859-3

10.1002/bjs.9856

10.1007/s00423-012-1006-9

10.1080/13651820310017093

10.1097/SLA.0b013e31825ffbfb

10.1097/SLA.0000000000000814

10.1245/s10434-015-4861-0

10.1016/j.surg.2012.05.017

10.1038/modpathol.3800685

10.1111/j.1477-2574.2009.00140.x

10.1245/s10434-008-9839-8

10.1002/bjs.5397

10.1002/bjs.9892

10.1001/archsurg.1985.01390320023003

10.1056/NEJMoa032295

10.1001/jama.2013.279201

10.1001/jama.297.3.267

10.1001/jama.299.9.1019

10.1245/s10434-011-1630-6

10.1001/jama.2010.1275

10.1200/jco.2013.31.15_suppl.4008

10.1200/JCO.2006.07.5663

10.1002/cncr.22735

Hammel P , HuguetF, Van LaethemJet al. Comparison of chemoradiotherapy (CRT) and chemotherapy (CT) in patients with a locally advanced pancreatic cancer (LAPC) controlled after 4 months of gemcitabine with or without erlotinib: final results of the international Phase III LAP 07 study. J. Clin. Oncol.31(Suppl. 18), Abstract LBA4003 (2013).

10.1200/JCO.1997.15.6.2403

10.1200/JCO.2006.07.9525

10.1056/NEJMoa1011923

10.1056/NEJMoa1304369

10.1016/j.ejca.2011.04.011

10.1200/JCO.2013.53.6995

10.1200/jco.2014.32.15_suppl.4022

10.1016/S0140-6736(15)00986-00981

10.1200/JCO.2012.43.3680

Haywood A , GoodP, KhanSet al. Corticosteroids for the management of cancer-related pain in adults. Cochrane Database Syst. Rev.4, CD010756 (2015).

10.1159/000199441

10.1016/j.critrevonc.07.014

10.1136/gut.42.1.92

10.1016/j.clnu.2003.07.001

10.1200/JCO.2012.44.4661

10.1002/14651858.CD004200.pub2

10.1111/hpb.12513

10.1007/s00432-014-1817-x

10.1126/science.1164368

10.1038/nature14169

10.1038/nature11547

10.1093/carcin/bgu193

10.1073/pnas.1501605112

10.1111/j.1477-2574.2012.00441.x

10.1073/pnas.1314307110

10.1016/j.gendis.2015.01.002

Hingorani S , HarrisW, HendifarAet al. High response rate and PFS with PEGPH20 added to nab-paclitaxel/gemcitabine in stage IV previously untreated pancreatic cancer patients with high-HA tumors: Interim results of a randomized Phase II study. J. Clin. Oncol.33(Suppl.), Abstract 4006 (2015).

Hingorani S , HarrisW, BeckJet al. Final results of a phase Ib study of gemcitabine plus PEGPH20 in patients with stage IV previously untreated pancreatic cancer. J. Clin. Oncol.33(Suppl. 3), Abstract 359 (2015).

10.4161/hv.34392

10.1158/2326-6066.CIR-15-0190

10.4161/21624011.2014.962401

10.3892/ijo.2012.1565

10.3390/cancers7030850

10.1002/stem.2114

10.1085/jgp.8.6.519

Warburg O . On the metabolism of carcinoma cells. Biochem. Z.152, 309–344 (1924).

10.1038/cddis.2014.38

10.1038/nature12040

10.1172/JCI72391

10.1371/journal.pone.0115153

10.1021/nn3043463

10.1016/j.cell.2011.02.013