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Nhiễm trùng nấm Paecilomyces variotii ở bệnh nhân u lympho cần ghép gan
Tóm tắt
Nấm Paecilomyces sp. đang trở thành những tác nhân gây bệnh mới nổi ở bệnh nhân suy giảm miễn dịch. Chúng tôi báo cáo một trường hợp nhiễm nấm Paecilomyces variotii, được điều trị thành công bằng amphotericin và anidulafungin, minh họa những khó khăn trong việc chẩn đoán sớm và lựa chọn liệu pháp đối với những nhiễm trùng nấm hiếm gặp như vậy.
Từ khóa
#nấm Paecilomyces #nhiễm trùng nấm #bệnh nhân suy giảm miễn dịch #amphotericin #anidulafungin #chẩn đoán sớm #u lympho #ghép ganTài liệu tham khảo
Luangsa-ard J, Houbraken J, Van Doorn T, Hong SB, Borman AM, Hywel-Jones NL, et al. Purpureocillium, a new genus for the medically important Paecilomyces lilacinus. FEMS Microbiol Lett. 2011;321:141–9.
Antas PR, Brito MM, Peixoto E, Ponte CG, Borba CM. Neglected and emerging fungal infections: review of hyalohyphomycosis by Paecilomyces lilacinus focusing in disease burden, in vitro antifungal susceptibility and management. Microbes Infect. 2012;14:1–8.
Pastor FJ, Guarro J. Clinical manifestations, treatment and outcome of Paecilomyces lilacinus infections. Clin Microbiol Infect. 2006;12:948–60.
Chang BP, Sun PL, Huang FY, Tsai TC, Lin CC, Lee MD, et al. Paecilomyces lilacinus peritonitis complicating peritoneal dialysis cured by oral voriconazole and terbinafine combination therapy. J Med Microbiol. 2008;57:1581–4.
Keshtar-Jahromi M, McTigue AH, Segalman KA, Fothergill AW, Campbell WN. Unusual case of cutaneous and synovial Paecilomyces lilacinus infection of hand successfully treated with voriconazole and review of published literature. Mycopathologia. 2012;174:255–8.
Labriola L, Vandercam B, Swinne D, Jadoul M. Successful treatment with voriconazole of prolonged Paecilomyces lilacinus fungemia in a chronic hemodialized patient. Clin Nephrol. 2009;71:355–8.
Lavergne RA, Cassaing S, Nocera T, Pauwels C, Cointault O, Basse G, et al. Simultaneous cutaneous infection due to Paecilomyces lilacinus and Alternaria in a heart transplant patient. Transpl Infect Dis. 2012;14:e156–60.
Saghrouni F, Saidi W, Ben Said Z, Gheith S, Ben Said M, Ranque S, et al. Cutaneous hyalohyphomycosis caused by Purpureocillium lilacinum in an immunocompetent patient: case report and review. Med Mycol. 2013;51:664–8.
Wolley M, Collins J, Thomas M. Paecilomyces lilacinus peritonitis in a peritoneal dialysis patient. Perit Dial Int. 2012;32:364–5.
Houbraken J, Verweij PE, Rijs AJ, Borman AM, Samson RA. Identification of Paecilomyces variotii in clinical samples and settings. J Clin Microbiol. 2010;48:2754–61.
Chamilos G, Kontoyiannis DP. Voriconazole-resistant disseminated Paecilomyces variotii infection in a neutropenic patient with leukaemia on voriconazole prophylaxis. J Infect. 2005;51:e225–8.
Drogari-Apiranthitou M, Mantopoulou FD, Skiada A, Kanioura L, Grammatikou M, Vrioni G, et al. In vitro antifungal susceptinility of filamentous fungi causing rare infections: synergy testing of amphotericin B, posaconazole and anidulafungin in pairs. J Antimicrob Chemother. 2012;67:1937–40.
Salle V, Lecuyer E, Chouaki T, Lescure FX, Smail A, Vaidie A, et al. Paecilomyces variotii fungemia in a patient with multiple myeloma: case report and literature review. J Infect. 2005;51:e93–5.
Polat M, Kara SS, Tapısız A, Demirtaş Z, Sarı S, Kalkancı A, et al. Successful treatment of Paecilomyces variotii peritonitis in a liver transplant patient. Mycopathologia. 2015;179:317–20.
Feldman R, Cockerham L, Buchan BW, Lu Z, Huang AM. Treatment of Paecilomyces variotii pneumonia with posaconazole: case report and literature review. Mycoses. 2016;. doi:10.1111/myc.12525 [Epub ahead of print].
Castelli MV, Alastruey-Izquierdo A, Cuest I, Monzon A, Mellado E, Rodriguez-Tudela JL, et al. Susceptibility testing and molecular classification of Paecilomyces spp. Antimicrob Agents Chemother. 2008;52:2926–8.
De Hoog GS, Guarro J, Gene J, Figueras MJ. Atlas of clinical fungi. 2nd ed. Baarn: Centraalbureau voor schimmelcultures; 2000. p. 794–809.
White TJ, Bruns T, Lee S, Taylor J. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics. In: Innis MA, Gelfand DH, Sninsky JJ, White TJ, editors. PCR protocols: a guide to methods and applications. San Diego: Academic Press Inc.; 1990. p. 315–22.
Bourdelin M, Grenouillet F, Daguindau E, Muret P, Desbrosses Y, Dubut J, et al. Posaconazole prophylaxis in neutropenic patients with hematological malignancies: limits in clinical practice. Med Mycol. 2014;52:728–35.
Dolton MJ, Ray JE, Marriott D, McLachlan AJ. Posaconazole exposure-response relationship: evaluating the utility of therapeutic drug monitoring. Antimicrob Agents Chemother. 2012;56:2806–13.
Panasiuk A, Wysocka J, Maciorkowska E, Panasiuk B, Prokopowicz D, Zak J, Radomski K. Phagocytic and oxydative burst activity of neutrophils in the end stage of liver cirrhosis. World J Gastroenterol. 2005;11:7661–5.
Falcone M, Massetti AP, Russo A, Vullo V, Venditti M. Invasive aspergillosis in patients with liver disease. Med Mycol. 2011;49:406–13.
Steiner B, Aquino VR, Paz AA, Silla LM, Zavascki A, Goldani LZ. Paecilomyces variotii as an emergent pathogenic agent of pneumonia. Case Rep Infect Dis. 2013. doi:10.1155/2013/273848.
Das A, MacLaughlin EF, Ross LA, Monforte HL, Horn MV, Lam GL, et al. Paecilomyces variotii in a pediatric patient with lung transplantation. Pediatr Transpl. 2000;4(4):328–32.
Byrd RP, Roy TM, Fields CM, Lynch JA. Paecilomyces variotii pneumonia in a patient with diabetes mellitus. J Diabetes Complicat. 1992;6:150–3.
Abolghasemi S, Tabarsi P, Adimi P, Kiani A, Dolatshahi S, Mansouri D. Pulmonary paecilomyces in a diabetic patient. Tanaffos. 2015;14(4):268–71.
Torres R, Gonzalez M, Sanhueza M, Segovia E, Alvo M, Passalacqua W, et al. Outbreak of Paecilomyces variotii peritonitis in peritoneal dialysis patients after the 2010 Chilean earthquake. Perit Dial Int. 2014;34(3):322–5.
Rinaldi S, Fiscarelli E, Rizzoni G. Paecilomyces variotii peritonitis in an infant on automated peritoneal dialysis. Pediatr Nephrol. 2000;14(5):365–6.
Marzec A, Heron LG, Pritchard RC, Butcher RH, Powell HR, Disney AP, et al. Paecilomyces variotii in peritoneal dialysate. J Clin Microbiol. 1993;31(9):2392–5.
Lee J, Yew WW, Chiu CS, Wong PC, Wong CF, Wang EP. Delayed sternotomy wound infection due to Paecilomyces variotii in a lung transplant recipient. J Heart Lung Transpl. 2002;21(10):1131–4.
Cohen-Abbo A, Edwards KM. Multifocal osteomyelitis caused by Paecilomyces variotii in a patient with chronic granulomatous disease. Infection. 1995;23(1):55–7.
Anita KB, Fernandez V, Rao R. Fungal endophthalmitis caused by Paecilomyces variotii, in an immunocompetent patient, following intraocular lens implantation. Indian J Med Microbiol. 2010;28(3):253–4.
Tarkkanen A, Raivio V, Anttila VJ, Tommila P, Ralli R, Merenmies L, et al. Fungal endophthalmitis caused by Paecilomyces variotii following cataract surgery: a presumed operating room air-conditioning system contamination. Acta Ophthalmol Scand. 2004;82(2):232–5.
Thompson RF, Bode RB, Rhodes JC, Gluckman JL. Paecilomyces variotii: An unusual cause of isolated sphenoid sinusitis. Arch Otolaryngol Head Neck Surg. 1988;114(5):567–9.
Swami T, Pannu S, Kumar M, Gupta G. Chronic invasive fungal rhinosinusitis by Paecilomyces variotii: a rare case report. Indian J Med Microbiol. 2016;34(1):103–6.
Lamoth F, Damonti L, Alexander BD. Role of antifungal susceptibility testing in non-aspergillus invasive mold infections. J Clin Microbiol. 2016;54:1638–40.
Tortorano AM, Richardson M, Roilides E, van Diepeningen A, Caira M, Munoz P, et al. European Society of Clinical Microbiology and Infectious Diseases Fungal Infection Study Group; European Confederation of Medical Mycology. ESCMID and ECMM joint guidelines on diagnosis and management of hyalohyphomycosis: Fusarium spp., Scedosporium spp. and others. Clin Microbiol Infect. 2014;20:27–46.
Barker AP, Horan JL, Slechta ES, Alexander BD, Hanson KE. Complexities associated with the molecular and proteomic identification of Paecilomyces species in the clinical mycology laboratory. Med Mycol. 2014;52(5):537–45.
Sganga G, Pepe G, Cozza V, Nure E, Lirosi MC, Frongillo F, et al. Anidulafungin—a new therapeutic option for Candida infections in liver transplantation. Transpl Proc. 2012;44:1982–5.