PYRIMIDINE DIMER FORMATION IN ULTRAVIOLET IRRADIATED TMV‐RNA

Photochemistry and Photobiology - Tập 6 Số 5 - Trang 309-319 - 1967
Virginia Merriam1, Milton P. Gordon1
1Department of Biochemistry, University of Washington, Seattle, Washington

Tóm tắt

Abstract— The formation of pyrimidine dimers on ultraviolet irradiation of TMV‐RNA in water is demonstrated in the region from 254 nm to 302 nm. No dimer is present in either unirradiated E. coli ribosomal RNA or TMV‐RNA. Dimer formation was also examined in TMV‐RNA irradiated in the presence of 5times10‐6 M proflavin, in high salt, on dry ice, and in 90% methanol. No correlation of pyrimidine dimers with any biologically defined lesion is presently possible and it is suggested that dimer may not be involved in the inactivation of this material.

Từ khóa


Tài liệu tham khảo

10.1016/B978-1-4832-2739-9.50014-4

10.1073/pnas.51.2.293

10.1073/pnas.53.6.1430

Elder R. L., 1965, J. Bacteriol., 90, 681, 10.1128/jb.90.3.681-686.1965

RÖrsch A., 1964, Biochim. et Biophys. Acta., 80, 246

10.1016/S0022-2836(64)80037-1

Grossman L., 1966, Federation Proc., 25, 276

10.1073/pnas.50.4.657

Grossman L., 1965, Federation Proc., 24, 5

10.1016/S0022-2836(65)80014-6

10.1016/S0022-2836(66)80181-X

10.1515/bchm2.1964.336.1.176

10.1111/j.1751-1097.1963.tb08907.x

10.1111/j.1751-1097.1965.tb07943.x

Schuster V. H., 1964, Z. Naturforsch, 19, 815, 10.1515/znb-1964-0909

10.1073/pnas.54.4.1261

Hatchard C. G., 1956, Proc. Roy. Soc., London, 236, 578

Wang S‐Y, 1965, Federation Proc, 24, 5

10.1111/j.1751-1097.1963.tb08908.x

10.1042/bj0550774

10.1016/S0022-2836(65)80148-6

10.1016/S0076-6879(57)03449-7

10.1016/0006-3002(52)90147-9

10.1073/pnas.47.10.1564

10.1073/pnas.53.3.653

Knight C. A., 1962, Biochem. Preparations, 9, 132

10.1073/pnas.45.3.313

G.Small(unpublished).

Lane B. G., 1963, Biochim. et Biophys. Acta., 72, 110, 10.1016/0926-6550(63)90316-5

10.1016/S0022-2836(63)80035-2

10.1073/pnas.53.5.1111

10.1016/S0022-2836(66)80105-5

10.1111/j.1751-1097.1965.tb07942.x

S.Sastry (unpublished).

H. A.Lozeron (unpublished).

10.1016/S0022-2836(64)80037-1

10.1126/science.142.3598.1464

Sauerbier W., 1964, Biochim. et Biophys. Acta., 87, 356

10.1016/S0022-2836(64)80018-8

10.1007/BF00894915

10.1021/bi00876a051

10.1016/0006-3002(57)90397-9

10.1021/bi00892a007

10.1021/bi00900a009

10.1111/j.1751-1097.1965.tb09770.x

M.Pearson Ph.D. thesis Univ. of Toronto (1966).

McLaren A. D., 1964, Photochem. of Proteins and Nucleic Acids