PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

Elsevier BV - Tập 13 - Trang 669-683 - 2019
Henna Konttinen1, Mauricio e Castro Cabral-da-Silva2, Sohvi Ohtonen1, Sara Wojciechowski1, Anastasia Shakirzyanova1, Simone Caligola3, Rosalba Giugno3, Yevheniia Ishchenko1, Damián Hernández4,5,6, Mohammad Feroze Fazaludeen1, Shaila Eamen1, Mireia Gómez Budia1, Ilkka Fagerlund1, Flavia Scoyni1, Paula Korhonen1, Nadine Huber1, Annakaisa Haapasalo1, Alex W. Hewitt4,5,7, James Vickers8, Grady C. Smith2
1A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland
2School of Chemistry and Molecular Bioscience, Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia
3Department of Computer Science, University of Verona, Verona 37134, Italy
4Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, VIC 3002, Australia
5Department of Surgery, the University of Melbourne, Melbourne, VIC 3002, Australia
6Department of Anatomy and Neuroscience, the University of Melbourne, Melbourne, VIC 3002, Australia
7School of Medicine, Menzies Institute for Medical Research, University of Tasmania, Hobart, VIC 7005, Australia
8Wicking Dementia Research and Education Centre, University of Tasmania, Hobart, TAS 7000, Australia

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