PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1

PLoS ONE - Tập 8 Số 9 - Trang e74710
Courtney Nicholas1, Jennifer Yang1, Sara Peters2, Matthew A. Bill1, Robert A. Baiocchi3, Fengting Yan3, Saı̈d Sif4, Sookil Tae4, Eugenio Gaudio5, Xin Wu6, Michael R. Grever3, Gregory Young7, Gregory B. Lesinski1
1Department of Internal Medicine, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America.
2Department of Pathology, Division of Dermatopathology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
3Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
4Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America.
5Department of Molecular, Virology, Immunology, and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America
6The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
7Center for Biostatistics, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, Ohio, United States of America

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