PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1
Tóm tắt
Từ khóa
Tài liệu tham khảo
CD Krause, 2007, Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential, Pharmacol Ther, 113, 50, 10.1016/j.pharmthera.2006.06.007
S Pal, 2007, Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma, EMBO J, 26, 3558, 10.1038/sj.emboj.7601794
S Pal, 2007, Interplay between chromatin remodelers and protein arginine methyltransferases, J Cell Physiol, 213, 306, 10.1002/jcp.21180
MA Powers, 2011, Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4, Cancer Res, 71, 5579, 10.1158/0008-5472.CAN-11-0458
L Wang, 2008, Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells, Mol Cell Biol, 28, 6262, 10.1128/MCB.00923-08
Yan F. (2010) Targeting protein arginine methyltransferase 5 (PRMT5) enzyme over expression in high grade astrocytomas; abstract #1584; American Association for Cancer Research 2010 Annual Meeting; Apr 17–21, 2010 Washington, DC.
Gu Z, Gao S, Zhang F, Wang Z, Ma W, <etal>et al</etal>.. (2012) Protein arginine methyltransferase 5 is essential for growth of lung cancer cells. Biochem J.
Z Gu, 2012, Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells, PLoS One, 7, e44033, 10.1371/journal.pone.0044033
TY Wei, 2012, Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade, Cancer Sci, 103, 1640, 10.1111/j.1349-7006.2012.02367.x
X Bao, 2013, Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer, J Histochem Cytochem, 61, 206, 10.1369/0022155413475452
AF Bruns, 2009, Fibroblast growth factor 2 (FGF-2) is a novel substrate for arginine methylation by PRMT5, Biol Chem, 390, 59, 10.1515/BC.2009.001
M Jansson, 2008, Arginine methylation regulates the p53 response, Nat Cell Biol, 10, 1431, 10.1038/ncb1802
M Lacroix, 2008, The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5, EMBO Rep, 9, 452, 10.1038/embor.2008.45
G Nagamatsu, 2011, A germ cell-specific gene, Prmt5, works in somatic cell reprogramming, J Biol Chem, 286, 10641, 10.1074/jbc.M110.216390
P Andreu-Perez, 2011, Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF, Sci Signal, 4, ra58, 10.1126/scisignal.2001936
A Maloney, 2007, Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin, Cancer Res, 67, 3239, 10.1158/0008-5472.CAN-06-2968
TW Chuang, 2011, The exon junction complex component Y14 modulates the activity of the methylosome in biogenesis of spliceosomal small nuclear ribonucleoproteins, J Biol Chem, 286, 8722, 10.1074/jbc.M110.190587
Y Feng, 2011, Histone H4 acetylation differentially modulates arginine methylation by an in Cis mechanism, J Biol Chem, 286, 20323, 10.1074/jbc.M110.207258
W He, 2011, A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage, Nucleic Acids Res, 39, 4719, 10.1093/nar/gkq1264
JM Hsu, 2011, Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation, Nat Cell Biol, 13, 174, 10.1038/ncb2158
GA Jung, 2011, Methylation of eukaryotic elongation factor 2 induced by basic fibroblast growth factor via mitogen-activated protein kinase, Exp Mol Med, 43, 550, 10.3858/emm.2011.43.10.061
F Liu, 2011, JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation, Cancer Cell, 19, 283, 10.1016/j.ccr.2010.12.020
WW Tee, 2010, Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency, Genes Dev, 24, 2772, 10.1101/gad.606110
LA Garraway, 2005, Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma, Nature, 436, 117, 10.1038/nature03664
S Carreira, 2005, Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression, Nature, 433, 764, 10.1038/nature03269
AE Loercher, 2005, MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A, J Cell Biol, 168, 35, 10.1083/jcb.200410115
S Carreira, 2006, Mitf regulation of Dia1 controls melanoma proliferation and invasiveness, Genes Dev, 20, 3426, 10.1101/gad.406406
JM Kirkwood, 1999, Systemic interferon-alpha (IFN-α) treatment leads to Stat3 inactivation in melanoma precursor lesions, Mol Med, 5, 11, 10.1007/BF03402135
R Loewe, 2004, BRAF kinase gene V599E mutation in growing melanocytic lesions, J Invest Dermatol, 123, 733, 10.1111/j.0022-202X.2004.23402.x
P Aggarwal, 2010, Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase, Cancer Cell, 18, 329, 10.1016/j.ccr.2010.08.012
WJ Friesen, 2002, A novel WD repeat protein component of the methylosome binds Sm proteins, J Biol Chem, 277, 8243, 10.1074/jbc.M109984200
SL Guo, 2011, miR-148a promoted cell proliferation by targeting p27 in gastric cancer cells, Int J Biol Sci, 7, 567, 10.7150/ijbs.7.567
BS Haflidadottir, 2010, miR-148 regulates Mitf in melanoma cells, PLoS One, 5, e11574, 10.1371/journal.pone.0011574
F Ozsolak, 2008, Chromatin structure analyses identify miRNA promoters, Genes Dev, 22, 3172, 10.1101/gad.1706508
B Wang, 2012, miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients, Biochem Biophys Res Commun, 421, 4, 10.1016/j.bbrc.2012.03.025
KA Mowen, 2001, Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription, Cell, 104, 731, 10.1016/S0092-8674(01)00269-0
BP Pollack, 1999, The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity, J Biol Chem, 274, 31531, 10.1074/jbc.274.44.31531
H Tanaka, 2009, PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation, Mol Cancer Res, 7, 557, 10.1158/1541-7786.MCR-08-0197
S Pal, 2004, Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes, Mol Cell Biol, 24, 9630, 10.1128/MCB.24.21.9630-9645.2004
S Pal, 2003, mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad, Mol Cell Biol, 23, 7475, 10.1128/MCB.23.21.7475-7487.2003
A Scoumanne, 2009, PRMT5 is required for cell-cycle progression and p53 tumor suppressor function, Nucleic Acids Res, 37, 4965, 10.1093/nar/gkp516
Yan F, Smith P, Alinari L, Ryu J, Yu B, <etal>et al</etal>.. (2011) Developing a Novel Class of Drug to Inhibit Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Dysregulation in Mantle Cell Lymphoma. ASH Annual Meeting Abstracts 118: abstract #595.
S Majumder, 2010, Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription, J Cell Biochem, 109, 553, 10.1002/jcb.22432
T Budden, 2013, The Role of Altered Nucleotide Excision Repair and UVB-Induced DNA Damage in Melanomagenesis, Int J Mol Sci, 14, 1132, 10.3390/ijms14011132
HY Handoko, 2013, UVB-Induced Melanocyte Proliferation in Neonatal Mice Driven by CCR2-Independent Recruitment of Ly6c(low)MHCII(hi) Macrophages, J Invest Dermatol, 133, 1803, 10.1038/jid.2013.9
W Wang, 2008, STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNα therapy, J Invest Dermatol, 128, 1997, 10.1038/jid.2008.26
SR Kanade, 2012, Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation, J Biol Chem, 287, 7313, 10.1074/jbc.M111.331660
DJ Terris, 1994, Oxygen tension measurements of head and neck cancers, Arch Otolaryngol Head Neck Surg, 120, 283, 10.1001/archotol.1994.01880270031006
A Hartmann, 1999, Hypoxia-induced up-regulation of angiogenin in human malignant melanoma, Cancer Res, 59, 1578
TJ Hemesath, 1994, microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family, Genes Dev, 8, 2770, 10.1101/gad.8.22.2770
Y Cheli, 2011, Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny, Oncogene, 30, 2307, 10.1038/onc.2010.598
C Wellbrock, 2008, Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF, PLoS One, 3, e2734, 10.1371/journal.pone.0002734
N Dumaz, 2006, In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling, Cancer Res, 66, 9483, 10.1158/0008-5472.CAN-05-4227
MA Bill, 2010, The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity, Mol Cancer, 9, 165, 10.1186/1476-4598-9-165
GB Lesinski, 2008, IFN-alpha and bortezomib overcome Bcl-2 and Mcl-1 overexpression in melanoma cells by stimulating the extrinsic pathway of apoptosis, Cancer Res, 68, 8351, 10.1158/0008-5472.CAN-08-0426