PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Nature Genetics - Tập 34 Số 3 - Trang 267-273 - 2003
Vamsi K. Mootha1, Cecilia M. Lindgren1, Karl‐Fredrik Eriksson2, Aravind Subramanian1, Smita Sihag1, Joseph Lehár1, Pere Puigserver3, Enar Carlsson2, Martin Ridderstråle2, Esa Laurila2, Nicholas Houstis1, Mark J. Daly1, Alkes L. Price1, Jill P. Mesirov1, Todd R. Golub1, Pablo Tamayo1, Bruce M. Spiegelman3, Eric S. Lander4, Joel N. Hirschhorn1, David Green5, Leif Groop2
1Whitehead Institute/MIT Center for Genome Research, Cambridge, Massachusetts, USA
2Department of Endocrinology, Wallenberg Laboratory, University Hospital MAS, Lund University, Malmo, S-205 02, Sweden
3Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA
4Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts (USA)
5Department of Medicine, Harvard Medical School, Boston, Massachusetts USA

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