PD-L1 expression in cancer patients receiving anti PD-1/PD-L1 antibodies: A systematic review and meta-analysis
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Akbay, 2013, Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors, Cancer Discov., 3, 1355, 10.1158/2159-8290.CD-13-0310
Atkinson V., Ascierto P.A., Long G.V., Brady B., Dutriaux C., Maio M., et al., 2015. Two-year Survival and Safety Update in Patients With Treatment-naïve Advanced Melanoma Receiving Nivolumab or Dacarbazine in CheckMate 066, SMR.
Azuma, 2014, Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancer, Ann. Oncol., 25, 1935, 10.1093/annonc/mdu242
Berry, 2015, Innate vs: adaptive: pD-L1-mediated immune resistance by melanoma, Oncoimmunology, 4, e1029704, 10.1080/2162402X.2015.1029704
Callea, 2015, Differential expression of PD-L1 between primary and metastatic sites in clear-cell renal cell carcinoma, Cancer Immunol. Res., 3, 1158, 10.1158/2326-6066.CIR-15-0043
Chen, 2015, Regulation of PD-L1: a novel role of pro-survival signalling in cancer, Ann. Oncol.
Choueiri T.K., Fishman M.N. Escudier B., Kim J.J., Kluger H., Stadler H., et al., 2014. Immunomodulatory activity of nivolumab in previously treated and untreated metastatic renal cell carcinoma (mRCC): biomarker-based results from a randomized clinical trial:ASCO.
D'Incecco, 2015, PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients, Br. J. Cancer, 112, 95, 10.1038/bjc.2014.555
Daud, 2014, Relationship between programmed death ligand 1 (PD-L1) expression and clinical outcome in patients (pts) with melanoma (MEL) treated with pembrolizumab (pembro; MK-3475), Eur. J. Cancer, 50, 48, 10.1016/S0959-8049(14)70266-7
Garon, 2015, Pembrolizumab for the treatment of non-small-cell lung cancer, N. Engl. J. Med., 372, 2018, 10.1056/NEJMoa1501824
Gettinger, 2015, Overall survival and long-term safety of nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer, J. Clin. Oncol., 33, 2004, 10.1200/JCO.2014.58.3708
Gibney, 2015, Safety, correlative markers, and clinical results of adjuvant nivolumab in combination with vaccine in resected high-risk metastatic melanoma, Clin. Cancer Res., 21, 712, 10.1158/1078-0432.CCR-14-2468
Greenland, 1987, Quantitative methods in the review of epidemiologic literature, Epidemiol. Rev., 9, 1, 10.1093/oxfordjournals.epirev.a036298
Herbst, 2014, Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients, Nature, 515, 563, 10.1038/nature14011
Hodi F.S., Sznol M., Kluger H.M., McDermott D.F., Carvajal R.D., Lawrence D.P., et al., 2014. Long-term survival of ipilimumab-naïve patients (pts) with advanced melanoma (MEL) treated with nivolumab (anti-PD-1; BMS-936558; ONO-4538) in a phase I trial:ASCO.
Kohlhapp, 2015, Molecular pathways mechanism of action for talimogene laherparepvec, a new oncolytic virus immunotherapy, Clin. Cancer Res.
Konishi, 2004, B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression, Clin. Cancer Res., 10, 5094, 10.1158/1078-0432.CCR-04-0428
Larkin, 2015, Combined nivolumab and ipilimumab or monotherapy in untreated melanoma, N. Engl. J. Med., 373, 23, 10.1056/NEJMoa1504030
Macaskill, 2001, A comparison of methods to detect publication bias in meta-analysis, Stat. Med., 20, 641, 10.1002/sim.698
Madore, 2015, PD-L1 expression in melanoma shows marked heterogeneity within and between patients: implications for anti-PD-1/PD-L1 clinical trials, Pigm. Cell Melanoma Res., 28, 245, 10.1111/pcmr.12340
Massi, 2014, PD-L1 marks a subset of melanomas with a shorter overall survival and distinct genetic and morphological characteristics, Ann. Oncol., 25, 2433, 10.1093/annonc/mdu452
Massi, 2015, The status of PD-L1 and tumor-infiltrating immune cells predict resistance and poor prognosis in BRAFi-treated melanoma patients harboring mutant BRAFV600, Ann. Oncol., 10.1093/annonc/mdv255
McDermott, 2015, Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab, J. Clin. Oncol., 33, 2013, 10.1200/JCO.2014.58.1041
McLaughlin, 2015, Quantitative assessment of the heterogeneity of PD-L1 expression in non-small-cell lung cancer, JAMA Oncol., 1
Moher, 2001, The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials, JAMA, 285, 1987, 10.1001/jama.285.15.1987
Pardoll, 2012, The blockade of immune checkpoints in cancer immunotherapy, Nat. Rev. Cancer, 12, 252, 10.1038/nrc3239
Paz-Ares L., Horn L., Borghaei H., Spigel D.R., Steins M., Neal E., et al., 2015. Phase III, randomized trial (CheckMate 057) of nivolumab (NIVO) versus docetaxel (DOC) in advanced non-squamous (non-SQ) cell non-small cell lung cancer (NSCLC):ASCO.
Postow, 2015, Immune checkpoint blockade in cancer therapy, J. Clin. Oncol., 33, 1974, 10.1200/JCO.2014.59.4358
Postow, 2015, Nivolumab and ipilimumab versus ipilimumab in untreated melanoma, N. Engl. J. Med., 372, 2006, 10.1056/NEJMoa1414428
Ribas, 2015, Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial, Lancet Oncol., 10.1016/S1470-2045(15)00083-2
Robert, 2015, Nivolumab in previously untreated melanoma without BRAF mutation, N. Engl. J. Med., 372, 320, 10.1056/NEJMoa1412082
Robert, 2015, Pembrolizumab versus ipilimumab in advanced melanoma, N. Engl. J. Med., 372, 2521, 10.1056/NEJMoa1503093
Rozali, 2012, Programmed death ligand 2 in cancer-induced immune suppression, Clin. Dev. Immunol., 2012, 656340, 10.1155/2012/656340
Sakuishi, 2010, Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity, J. Exp. Med., 207, 2187, 10.1084/jem.20100643
Shin, 2015, The evolution of checkpoint blockade as a cancer therapy: what's here, what's next, Curr. Opin. Immunol., 33, 23, 10.1016/j.coi.2015.01.006
Spira A.I., Park K., Mazieres J., Vansteenkiste J., Rittmeyer A., Ballinger M., et al., 2015. Efficacy, safety and predictive biomarker results from a randomized Phase II study comparing atezolizumab (MPDL3280A) vs docetaxel in 2L/3L NSCLC (POPLAR):ASCO.
Spranger, 2014, Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment, J. Immunother. Cancer, 2
Stuart, 1994
Sznol, 2013, Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer-response, Clin. Cancer Res., 19
Taube, 2012, Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape, Sci. Transl. Med., 4, 10.1126/scitranslmed.3003689
Taube, 2014, Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy, Clin. Cancer Res., 20, 5064, 10.1158/1078-0432.CCR-13-3271
Therasse, 2000, New guidelines to evaluate the response to treatment in solid tumors European Organization for Research and Treatment of Cancer. National Cancer Institute of the United States, National Cancer Institute of Canada, J. Natl. Cancer Inst., 92, 205, 10.1093/jnci/92.3.205
Thompson, 2004, Costimulatory B7-H1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target, Proc. Natl. Acad. Sci. U. S. A., 101, 17174, 10.1073/pnas.0406351101
Topalian, 2012, Safety, activity, and immune correlates of anti-PD-1 antibody in cancer, N. Engl. J. Med., 366, 2443, 10.1056/NEJMoa1200690
Tumeh, 2014, PD-1 blockade induces responses by inhibiting adaptive immune resistance, Nature, 515, 568, 10.1038/nature13954
Wainwright, 2014, Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors, Clin. Cancer Res., 20, 5290, 10.1158/1078-0432.CCR-14-0514
Wargo, 2014, Universes collide: combining immunotherapy with targeted therapy for cancer, Cancer Discov., 4, 1377, 10.1158/2159-8290.CD-14-0477
Weber, 2013, Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or -naive melanoma, J. Clin. Oncol., 31, 4311, 10.1200/JCO.2013.51.4802
Wolchok, 2013, Nivolumab plus ipilimumab in advanced melanoma, N. Engl. J. Med., 369, 122, 10.1056/NEJMoa1302369
Wolchok J.D., Chiarion-Sileni V., Gonzalez R., Rutkowski P., Grob J.-, Cowey C.L., et al., 2015. Efficacy and safety results from a Phase III trial of nivolumab slone or combined with ipilimumab vs. ipilimumab alone in treatment-naïve patients with advanced melanoma (CheckMate 067); Abstract #LBA1:ASCO.
Woo, 2012, Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape, Cancer Res., 72, 917, 10.1158/0008-5472.CAN-11-1620
Yoshii, 2009, Analysis of the reporting of search strategies in Cochrane systematic reviews, J. Med. Libr. Assoc., 97, 21, 10.3163/1536-5050.97.1.004
van Houwelingen, 2002, Advanced methods in meta-analysis: multivariate approach and meta-regression, Stat. Med., 21, 589, 10.1002/sim.1040