Oxidative stress-related aging: A role for prostate cancer?

Barja, 2002, Rate of generation of oxidative stress-related damage and animal longevity, Free Radic. Biol. Med., 33, 1167, 10.1016/S0891-5849(02)00910-3 Martin, 2007, The pathology of ageing: concepts and mechanisms, J. Pathol., 211, 111, 10.1002/path.2122 Somel, 2006, Gene expression becomes heterogeneous with age, Curr. Biol., 16, R359, 10.1016/j.cub.2006.04.024 de Grey, 2007, Protagonistic pleiotropy: why cancer may be the only pathogenic effect of accumulating nuclear mutations and epimutations in aging, Mech. Ageing Dev., 128, 456, 10.1016/j.mad.2007.05.005 Xue, 2007, A modular network model of aging, Mol. Syst. Biol., 3, 147, 10.1038/msb4100189 Howitz, 2003, Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan, Nature, 425, 191, 10.1038/nature01960 Sauve, 2006, The biochemistry of sirtuins, Annu. Rev. Biochem., 75, 435, 10.1146/annurev.biochem.74.082803.133500 Sinclair, 2005, Toward a unified theory of caloric restriction and longevity regulation, Mech. Ageing Dev., 126, 987, 10.1016/j.mad.2005.03.019 Michan, 2007, Sirtuins in mammals: insights into their biological function, Biochem. J., 404, 1, 10.1042/BJ20070140 Yamamoto, 2007, Sirtuin functions in health and disease, Mol. Endocrinol., 21, 1745, 10.1210/me.2007-0079 Dröge, 2007, Oxidative stress and aberrant signaling in aging and cognitive decline, Aging Cell, 6, 361, 10.1111/j.1474-9726.2007.00294.x Harman, 1956, Aging: a theory based on free radical and radiation chemistry, J. Gerontol., 11, 298, 10.1093/geronj/11.3.298 Harman, 1972, The biologic clock: the mitochondria?, J. Am. Geriatr. Soc., 20, 145, 10.1111/j.1532-5415.1972.tb00787.x Balaban, 2005, Mitochondria, oxidants, and aging, Cell, 120, 483, 10.1016/j.cell.2005.02.001 Giorgio, 2007, Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?, Nat. Rev. Mol. Cell. Biol., 8, 722, 10.1038/nrm2240 Muller, 2007, Trends in oxidative aging theories, Free Radic. Biol. Med., 43, 477, 10.1016/j.freeradbiomed.2007.03.034 Van Remmen, 2001, Oxidative damage to mitochondria and aging, Exp. Gerontol., 36, 957, 10.1016/S0531-5565(01)00093-6 Bokov, 2004, The role of oxidative damage and stress in aging, Mech. Ageing Dev., 125, 811, 10.1016/j.mad.2004.07.009 de Grey, 2002, The reductive hotspot hypothesis of mammalian aging: membrane metabolism magnifies mutant mitochondrial mischief, Eur. J. Biochem., 269, 2003, 10.1046/j.1432-1033.2002.02868.x Tolmasoff, 1980, Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species, Proc. Natl. Acad. Sci. U. S. A., 77, 2777, 10.1073/pnas.77.5.2777 Chahal, 2007, The endocrine system and ageing, J. Pathol., 211, 173, 10.1002/path.2110 Borras, 2007, Mitochondrial oxidant generation is involved in determining why females live longer than males, Front Biosci., 12, 1008, 10.2741/2120 Frisard, 2006, Energy metabolism and oxidative stress: impact on the metabolic syndrome and the aging process, Endocrine, 29, 27, 10.1385/ENDO:29:1:27 Finkel, 2001, Reactive oxygen species and signal transduction, IUBMB Life, 52, 3, 10.1080/15216540252774694 Kops, 2002, Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress, Nature, 419, 316, 10.1038/nature01036 Migliaccio, 2006, Apoptosis and aging: role of p66Shc redox protein, Antioxid. Redox. Signal, 8, 600, 10.1089/ars.2006.8.600 Zhang, 2006, Mechanistic studies of the Nrf2-Keap1 signaling pathway, Drug Metab. Rev., 38, 769, 10.1080/03602530600971974 Sablina, 2005, The antioxidant function of the p53 tumor suppressor, Nat. Med., 11, 1306, 10.1038/nm1320 Migliaccio, 1999, The p66shc adaptor protein controls oxidative stress response and life span in mammals, Nature, 402, 309, 10.1038/46311 Schriner, 2005, Extension of murine life span by overexpression of catalase targeted to mitochondria, Science, 308, 1909, 10.1126/science.1106653 Serrano, 2007, Cancer and ageing: convergent and divergent mechanisms, Nat. Rev. Mol. Cell Biol., 8, 715, 10.1038/nrm2242 Bracarda, 2005, Cancer of the prostate, Crit. Rev. Oncol. Hematol., 56, 379, 10.1016/j.critrevonc.2005.03.010 Bostwick, 2004, Human prostate cancer risk factors, Cancer, 101, 2371, 10.1002/cncr.20408 Sakr, 2004, Potential pathologic markers for prostate chemoprevention studies, Urol. Clin. North Am., 31, 227, 10.1016/j.ucl.2004.03.001 Pathak, 2003, Chemoprevention of prostate cancer by diet-derived antioxidant agents and hormonal manipulation, Int. J. Oncol., 22, 5 Heinonen, 1998, Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial, J. Natl. Cancer. Inst., 90, 440, 10.1093/jnci/90.6.440 Omenn, 1996, Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial, J. Natl. Cancer Inst., 88, 1550, 10.1093/jnci/88.21.1550 Willett, 1984, Relation of serum vitamins A and E and carotenoids to the risk of cancer, N. Engl. J. Med., 310, 430, 10.1056/NEJM198402163100705 Klein, 2003, SELECT: the selenium and vitamin E cancer prevention trial, Urol. Oncol., 21, 59, 10.1016/S1078-1439(02)00301-0 Feng, 2008, The tumor suppressor p53: cancer and aging, Cell Cycle, 7, 842, 10.4161/cc.7.7.5657 Chen, 2005, Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis, Nature, 436, 725, 10.1038/nature03918 Huffman, 2007, SIRT1 is significantly elevated in mouse and human prostate cancer, Cancer Res., 67, 6612, 10.1158/0008-5472.CAN-07-0085 Blasco, 2007, The epigenetic regulation of mammalian telomeres, Nat. Rev. Genet., 8, 299, 10.1038/nrg2047 Sharpless, 2005, INK4a/ARF: a multifunctional tumor suppressor locus, Mutat. Res., 576, 22, 10.1016/j.mrfmmm.2004.08.021 Shawi, 2008, Telomerase, senescence and ageing, Mech. Ageing Dev., 129, 3, 10.1016/j.mad.2007.11.007 Lesnefsky, 2006, Oxidative phosphorylation and aging, Ageing Res. Rev., 5, 402, 10.1016/j.arr.2006.04.001 Lopez-Lazaro, 2007, Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy, Cancer Lett., 252, 1, 10.1016/j.canlet.2006.10.029 Chang, 2008, PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression, Mol. Cell Biol., 28, 3281, 10.1128/MCB.00310-08 Sage, 2005, Making young tumors old: a new weapon against cancer?, Sci. Aging Knowledge Environ., 2005, pe25, 10.1126/sageke.2005.33.pe25 Mehraein-Ghomi, 2008, JunD mediates androgen-induced oxidative stress in androgen dependent LNCaP human prostate cancer cells, Prostate, 68, 924, 10.1002/pros.20737 Barqawi, 2006, Testosterone replacement therapy and the risk of prostate cancer. Is there a link?, Int. J. Impot. Res., 18, 323, 10.1038/sj.ijir.3901418 Raynaud, 2006, Prostate cancer risk in testosterone-treated men, J. Steroid. Biochem. Mol. Biol., 102, 261, 10.1016/j.jsbmb.2006.09.032 Montgomery, 2008, Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth, Cancer Res., 68, 4447, 10.1158/0008-5472.CAN-08-0249 Banerjee, 2001, Increased androgen receptor expression correlates with development of age-dependent, lobe-specific spontaneous hyperplasia of the brown Norway rat prostate, Endocrinology, 142, 4066, 10.1210/en.142.9.4066 Culig, 2002, Interleukin-6 regulates androgen receptor activity and prostate cancer cell growth, Mol. Cell Endocrinol., 197, 231, 10.1016/S0303-7207(02)00263-0 Culig, 2004, Expression and function of androgen receptor coactivators in prostate cancer, J. Steroid Biochem. Mol. Biol., 92, 265, 10.1016/j.jsbmb.2004.10.003 Hendriksen, 2006, Evolution of the androgen receptor pathway during progression of prostate cancer, Cancer Res., 66, 5012, 10.1158/0008-5472.CAN-05-3082 Holt, 2008, Association of megalin genetic polymorphisms with prostate cancer risk and prognosis, Clin. Cancer Res., 14, 3823, 10.1158/1078-0432.CCR-07-4566 Bektic, 2004, Identification of genes involved in estrogenic action in the human prostate using microarray analysis, Genomics, 83, 34, 10.1016/S0888-7543(03)00184-8 Sampson, 2007, The ageing male reproductive tract, J. Pathol., 211, 206, 10.1002/path.2077 Bosland, 2000, The role of steroid hormones in prostate carcinogenesis, J. Natl. Cancer Inst. Monogr., 39, 10.1093/oxfordjournals.jncimonographs.a024244 Prudova, 2007, Testosterone regulation of homocysteine metabolism modulates redox status in human prostate cancer cells, Antioxid. Redox. Signal, 9, 1875, 10.1089/ars.2007.1712 Pinthus, 2007, Androgen induces adaptation to oxidative stress in prostate cancer: implications for treatment with radiation therapy, Neoplasia, 9, 68, 10.1593/neo.06739 Miyake, 2004, Protection of androgen-dependent human prostate cancer cells from oxidative stress-induced DNA damage by overexpression of clusterin and its modulation by androgen, Prostate, 61, 318, 10.1002/pros.20087 Salm, 2005, TGF-{beta} maintains dormancy of prostatic stem cells in the proximal region of ducts, J. Cell Biol., 170, 81, 10.1083/jcb.200412015 Lee, 1999, Transforming growth factor-beta in benign and malignant prostate, Prostate, 39, 285, 10.1002/(SICI)1097-0045(19990601)39:4<285::AID-PROS9>3.0.CO;2-7 van der Poel, 2005, Androgen receptor and TGFbeta1/Smad signaling are mutually inhibitory in prostate cancer, Eur. Urol., 48, 1051, 10.1016/j.eururo.2005.09.006 Bruckheimer, 2002, Bcl-2 antagonizes the combined apoptotic effect of transforming growth factor-beta and dihydrotestosterone in prostate cancer cells, Prostate, 53, 133, 10.1002/pros.10143 Proell, 2007, TGF-beta dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells, Comp. Hepatol., 6, 1, 10.1186/1476-5926-6-1 Sancho, 2008, The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms, Biochim. Biophys. Acta Orimo, 2005, Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion, Cell, 121, 335, 10.1016/j.cell.2005.02.034 Hill, 2005, Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis, Cell, 123, 1001, 10.1016/j.cell.2005.09.030 Gennigens, 2006, Insulin-Like Growth Factor (IGF) family and prostate cancer, Crit. Rev. Oncol. Hematol., 58, 124, 10.1016/j.critrevonc.2005.10.003 Kawada, 2006, Insulin-like growth factor I secreted from prostate stromal cells mediates tumor–stromal cell interactions of prostate cancer, Cancer Res., 66, 4419, 10.1158/0008-5472.CAN-05-4239 Kojima, 2006, Differential regulation of IGFBP-3 by the androgen receptor in the lineage-related androgen-dependent LNCaP and androgen-independent C4-2 prostate cancer models, Prostate, 66, 971, 10.1002/pros.20420 Bavik, 2006, The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms, Cancer Res., 66, 794, 10.1158/0008-5472.CAN-05-1716 Fischer, 2004, Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor, Mol. Cell Biol., 24, 5172, 10.1128/MCB.24.12.5172-5183.2004 Karan, 2003, Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas, Int. J. Oncol., 23, 1365 Lim, 2005, Increased Nox1 and hydrogen peroxide in prostate cancer, Prostate, 62, 200, 10.1002/pros.20137 Carl-McGrath, 2005, The disintegrin-metalloproteinases ADAM9, ADAM12, and ADAM15 are upregulated in gastric cancer, Int. J. Oncol., 26, 17 Mochizuki, 2007, ADAMs in cancer cell proliferation and progression, Cancer Sci., 98, 621, 10.1111/j.1349-7006.2007.00434.x Nguyen, 2003, Regulatory mechanisms controlling gene expression mediated by the antioxidant response element, Annu. Rev. Pharmacol. Toxicol., 43, 233, 10.1146/annurev.pharmtox.43.100901.140229 Hanahan, 2000, The hallmarks of cancer, Cell, 100, 57, 10.1016/S0092-8674(00)81683-9 Shi, 2004, Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis, Mol. Cancer Res., 2, 395, 10.1158/1541-7786.395.2.7 Wu, 2006, The signaling mechanism of ROS in tumor progression, Cancer Metastasis Rev., 25, 695, 10.1007/s10555-006-9037-8 North, 2005, Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors, Cancer Lett., 218, 1, 10.1016/j.canlet.2004.08.007 Kaushal, 2006, Thrombin receptor expression is upregulated in prostate cancer, Prostate, 66, 273, 10.1002/pros.20326 Reed, 2007, The effects of aging on tumor growth and angiogenesis are tumor-cell dependent, Int. J. Cancer, 120, 753, 10.1002/ijc.22351 Reed, 2004, Impaired angiogenesis in the aged, Sci. Aging Knowl. Environ., 2004, pe7, 10.1126/sageke.2004.7.pe7 Campisi, 2005, Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors, Cell, 120, 513, 10.1016/j.cell.2005.02.003 Anisimov, 2006, Effect of host age on tumor growth rate in rodents, Front Biosci., 11, 412, 10.2741/1808 Bhowmick, 2004, TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia, Science, 303, 848, 10.1126/science.1090922 Krtolica, 2001, Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging, Proc. Natl. Acad. Sci. U. S. A., 98, 12072, 10.1073/pnas.211053698 Tam, 2007, Sex hormones induce direct epithelial and inflammation–mediated oxidative/nitrosative stress that favors prostatic carcinogenesis in the noble rat, Am. J. Pathol., 171, 1334, 10.2353/ajpath.2007.070199 Cheng, 2007, COX2 genetic variation, NSAIDs, and advanced prostate cancer risk, Br. J. Cancer, 97, 555, 10.1038/sj.bjc.6603874 Bao, 2008, Protective role of 1 alpha, 25-dihydroxyvitamin D3 against oxidative stress in nonmalignant human prostate epithelial cells, Int. J. Cancer, 22, 699 Lou, 2004, 25-hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells, FASEB J., 18, 332, 10.1096/fj.03-0140fje Schwartz, 2008, Vitamin D and intervention trials in prostate cancer: from theory to therapy, Ann. Epidemiol. Petrioli, 2007, Weekly high-dose calcitriol and docetaxel in patients with metastatic hormone-refractory prostate cancer previously exposed to docetaxel, BJU Int., 100, 775, 10.1111/j.1464-410X.2007.07019.x Gius, 2006, Redox signaling in cancer biology, Antioxid. Redox. Signal, 8, 1249, 10.1089/ars.2006.8.1249 Kwabi-Addo, 2007, Age-related DNA methylation changes in normal human prostate tissues, Clin. Cancer Res., 13, 3796, 10.1158/1078-0432.CCR-07-0085 Kumar, 2008, Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype, Cancer Res., 68, 1777, 10.1158/0008-5472.CAN-07-5259 Chaiswing, 2007, Characterization of redox state of two human prostate carcinoma cell lines with different degrees of aggressiveness, Free Radic. Biol. Med., 43, 202, 10.1016/j.freeradbiomed.2007.03.031 Malins, 2001, Age-related radical-induced DNA damage is linked to prostate cancer, Cancer Res., 61, 6025 Malins, 2003, Cancer-related changes in prostate DNA as men age and early identification of metastasis in primary prostate tumors, Proc. Natl. Acad. Sci. U. S. A., 100, 5401, 10.1073/pnas.0931396100 Bostwick, 2000, Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer, Cancer, 89, 123, 10.1002/1097-0142(20000701)89:1<123::AID-CNCR17>3.0.CO;2-9 Kobayashi, 2005, Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation, Antioxid. Redox. Signal, 7, 385, 10.1089/ars.2005.7.385 Frohlich, 2008, The role of Nrf2 in increased reactive oxygen species and DNA damage in prostate tumorigenesis, Oncogene, 10.1038/onc.2008.79 Motohashi, 2007, Carcinogenesis and transcriptional regulation through Maf recognition elements, Cancer Sci., 98, 135, 10.1111/j.1349-7006.2006.00358.x Nelson, 2004, The role of inflammation in the pathogenesis of prostate cancer, J. Urol., 172, S6, 10.1097/01.ju.0000142058.99614.ff Pathak, 2005, Oxidative stress and cyclooxygenase activity in prostate carcinogenesis: targets for chemopreventive strategies, Eur. J. Cancer, 41, 61, 10.1016/j.ejca.2004.09.028 Naber, 2000, Chronic prostatitis—an infectious disease?, J. Antimicrob. Chemother., 46, 157, 10.1093/jac/46.2.157 Palapattu, 2005, Prostate carcinogenesis and inflammation: emerging insights, Carcinogenesis, 26, 1170, 10.1093/carcin/bgh317 Ripple, 1997, Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells, J. Natl. Cancer Inst., 89, 40, 10.1093/jnci/89.1.40 Prins, 2008, The role of estrogens and estrogen receptors in normal prostate growth and disease, Steroids, 73, 233, 10.1016/j.steroids.2007.10.013 Reyes, 2005, Aging-associated changes in gene expression in the ACI rat prostate: implications for carcinogenesis, Prostate, 63, 169, 10.1002/pros.20164 Trzeciak, 2004, Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145, Carcinogenesis, 25, 1359, 10.1093/carcin/bgh144 Choi, 2007, Polymorphisms in oxidative stress-related genes are not associated with prostate cancer risk in heavy smokers, Cancer Epidemiol. Biomarkers Prev., 16, 1115, 10.1158/1055-9965.EPI-07-0040 Choi, 2008, Iron intake, oxidative stress-related genes (MnSOD and MPO) and prostate cancer risk in CARET cohort, Carcinogenesis, 29, 964, 10.1093/carcin/bgn056 Taufer, 2005, Is the Val16Ala manganese superoxide dismutase polymorphism associated with the aging process?, J. Gerontol. A. Biol. Sci. Med. Sci., 60, 432, 10.1093/gerona/60.4.432 Woodson, 2003, Manganese superoxide dismutase (MnSOD) polymorphism, alpha-tocopherol supplementation and prostate cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study (Finland), Cancer Causes Control, 14, 513, 10.1023/A:1024840823328 Villeponteau, 2000, Nutraceutical interventions may delay aging and the age-related diseases, Exp. Gerontol., 35, 1405, 10.1016/S0531-5565(00)00182-0