Oxidative metabolism of anandamide

Prostaglandins & Other Lipid Mediators - Tập 61 Số 1-2 - Trang 29-41 - 2000
Sumner Burstein1,2, Ronald G. Rossetti2, Boris Yagen1, Robert B. Zurier2
1Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655-0103, USA
2Department of Medicine, Division of Rheumatology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655-0103, USA

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Tài liệu tham khảo

Axelrod, 1998, Cannabinoid receptors and their endogenous agonist, anandamide, Neurochem Res, 23, 575, 10.1023/A:1022418217479

Di Marzo, 1999, Biosynthesis and inactivation of endocannabinoids, Life Sci, 65, 645, 10.1016/S0024-3205(99)00287-8

Hillard, 1997, Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid, J Lipid Res, 38, 2383, 10.1016/S0022-2275(20)30024-9

Zimmer, 1999, Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice, Proc Natl Acad Sci, 96, 5780, 10.1073/pnas.96.10.5780

Kruska, 1994, The ATP- and CoA-independent synthesis of arachidonoylethanolamide, J Biol Chem, 269, 14345

Burstein, 1995, Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by THC, Biochem Pharmacol, 49, 855, 10.1016/0006-2952(94)00538-W

Burstein, 1994, Phospholipase participation in cannabinoid-induced release of free arachidonic acid, Biochem Pharmacol, 48, 1253, 10.1016/0006-2952(94)90163-5

Ueda, 1995, Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide, J Biol Chem, 270, 23823, 10.1074/jbc.270.40.23823

Devane, 1994, Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes, Proc Natl Acad Sci USA, 91, 6698, 10.1073/pnas.91.14.6698

Di Marzo, 1994, Formation and inactivation of endogenous cannabinoid anandamide in central neurons, Nature, 372, 686, 10.1038/372686a0

Bisogno, 1997, Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes, J Biol Chem, 272, 3315, 10.1074/jbc.272.6.3315

Di Marzo, 1996, Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells, Biochem J, 316, 977, 10.1042/bj3160977

Hansen, 1998, Formation of N-acyl-phosphatidylethanolamines and N-acetylethanolamines, Biochem Pharmacol, 55, 719, 10.1016/S0006-2952(97)00396-1

Schmid, 1997, Anandamide and other N-acylethanolamines in mouse peritoneal macrophages, Chem Phys Lipids, 87, 103, 10.1016/S0009-3084(97)00032-7

Deutsch, 1993, Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist, Biochem Pharmacol, 46, 791, 10.1016/0006-2952(93)90486-G

Giang, 1997, Molecular characterization of human and mouse fatty acid amide hydrolases, Proc Natl Acad Sci, 94, 2238, 10.1073/pnas.94.6.2238

Ueda, 1995, Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist, Biochem Biophys Acta, 1254, 127, 10.1016/0005-2760(94)00170-4

Hampson, 1995, Anandamide hydroxylation by brain lipoxygenase, Biochem Biophys Acta, 1259, 173, 10.1016/0005-2760(95)00157-8

Edgemond, 1998, Human platelets and polymorphonuclear leukocytes synthesize derivatives of anandamide, Mol Pharmacol, 54, 180, 10.1124/mol.54.1.180

Yu, 1997, Synthesis of PGE2 ethanolamide from anandamide by COX-2, J Biol Chem, 272, 21181, 10.1074/jbc.272.34.21181

So O-Y, Scarafia LE, Mak AY, Callan OH, Swinney DCJ. Biol Chem 1998;273:5801–7.

Herschman, 1996, Prostaglandin synthase-2, Biochim Biophys Acta, 1299, 125, 10.1016/0005-2760(95)00194-8

Willoughby, 1997, The biodisposition and metabolism of anandamide in mice, J Pharm Exp Ther, 282, 243

Bornheim, 1993, The effect of cannabidiol on mouse hepatic microsomal cytochrome p-450 dependent anandamide metabolism, Biochem Biophys Res Comm, 197, 740, 10.1006/bbrc.1993.2541

Bornheim, 1995, Microsomal cytochrome p-450 mediated liver and brain anandamide metabolism, Biochem Pharmacol, 50, 677, 10.1016/0006-2952(95)00177-2

Merkler, 1996, Fatty acid amide biosynthesis, Arch Biochem Biophys, 330, 430, 10.1006/abbi.1996.0272

Wilcox BJ, Ritenour–Rogers J, Asser AS, Baumgart LE, Baumgart ME, Boger DL, DeBlassio JL, deLong MA, Glufke U, Henz ME, King L III, Merkler KA, Patterson JE, Robelski JJ, Vederas JC, Merkler DJ. N-acyl glycine amidation: implications for the biosynthesis of fatty acid primary amides.

Martinez, 1996, Where does amidation take place?, Mol Cell Endocr, 123, 113, 10.1016/S0303-7207(96)03903-2

Burstein S, Monaghan A, Pearson W, Rooney T, Yagen B, Zipkin R, Zurier A. Studies with analogs of anandamide and indomethacin. Proc ICRS 1997;XX:31.

Burstein, 1999, The cannabinoid acids, Pharmacol Therap, 82, 87, 10.1016/S0163-7258(98)00069-2

Pestonjamasp, 1998, Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system, Biochem Biophys Acta, 1394, 249, 10.1016/S0005-2760(98)00110-6

Goto, 1990, Spontaneous release of angiotensin converting enzyme and interleukin 1-b from peripheral blood monocytes from patients with rheumatoid arthritis under serum free conditions, Ann Rheum Dis, 49, 172, 10.1136/ard.49.3.172

Burstein, 1992, Synthetic non-psychotropic cannabinoids with potent anti-inflammatory, analgesic, and leukocyte antiadhesion activities, J Med Chem, 35, 3135, 10.1021/jm00095a007