Oxidative Stress: A Unifying Paradigm in Hypertension
Tóm tắt
Từ khóa
Tài liệu tham khảo
Harrison, 2013, The mosaic theory revisited: common molecular mechanisms coordinating diverse organ and cellular events in hypertension, J Am Soc Hypertens, 7, 68, 10.1016/j.jash.2012.11.007
Harvey, 2015, Vascular biology of ageing—implications in hypertension, J Mol Cell Cardiol, 8, 112, 10.1016/j.yjmcc.2015.04.011
Stanley, 2019, Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation, Nature, 5, 548, 10.1038/s41586-019-0947-3
Knock, 2019, NADPH oxidase in the vasculature: expression, regulation and signalling pathways; role in normal cardiovascular physiology and its dysregulation in hypertension, Free Radic Biol Med, 1, 385, 10.1016/j.freeradbiomed.2019.09.029
Lassegue, 2003, Vascular NAD(P)H oxidases: specific features, expression, and regulation, Am J Physiol Regul Integr Comp Physiol, 2, R277, 10.1152/ajpregu.00758.2002
Montezano, 2011, Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5, Clin Sci (Lond), 1, 131, 10.1042/CS20100384
Touyz, 2001, Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D–dependent NAD(P)H oxidase–sensitive pathways, J Hypertens, 1, 1245, 10.1097/00004872-200107000-00009
Zhang, 2020, NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets, Nat Rev Cardiol, 17, 170, 10.1038/s41569-019-0260-8
Dikalova, 2010, Therapeutic targeting of mitochondrial superoxide in hypertension, Circ, 1, 106
Dikalov, 2014, Nox2-induced production of mitochondrial superoxide in angiotensin II–mediated endothelial oxidative stress and hypertension, Antioxid Redox Signal, 2, 281, 10.1089/ars.2012.4918
Carlisle, 2016, Endoplasmic reticulum stress inhibition reduces hypertension through the preservation of resistance blood vessel structure and function, J Hypertens, 3, 1556, 10.1097/HJH.0000000000000943
Zinkevich, 2011, ROS-induced ROS release in vascular biology: redox-redox signaling, Am J Physiol, 3, H647
Koju, 2019, Pharmacological strategies to lower crosstalk between nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and mitochondria, Biomed Pharmacother, 1, 1478, 10.1016/j.biopha.2018.11.128
He, 2019, Inhibition of mitochondrial oxidative damage improves reendothelialization capacity of endothelial progenitor cells via SIRT3 (Sirtuin 3)–enhanced SOD2 (superoxide dismutase 2) deacetylation in hypertension, Arterioscler Thromb Vasc Biol, 3, 1682, 10.1161/ATVBAHA.119.312613
Rossman, 2018, Chronic supplementation with a mitochondrial antioxidant (MitoQ) improves vascular function in healthy older adults, Hypertension, 7, 1056, 10.1161/HYPERTENSIONAHA.117.10787
Chan, 2017, Mitochondria and reactive oxygen species contribute to neurogenic hypertension, Physiology (Bethesda), 3, 308
Camargo, 2018, Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension, Hypertension, 7, 235, 10.1161/HYPERTENSIONAHA.118.10824
Lushchak, 2014, Free radicals, reactive oxygen species, oxidative stress and its classification, Chem Biol Interact, 2, 164, 10.1016/j.cbi.2014.10.016
Lichtenberg, 2015, Oxidative stress, the term and the concept, Biochem Biophys Res Commun, 4, 441, 10.1016/j.bbrc.2015.04.062
Sies, 2017, Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: oxidative eustress, Redox Biol, 1, 613, 10.1016/j.redox.2016.12.035
Sies, 2018, On the history of oxidative stress: concept and some aspects of current development, Curr Opin Toxic, 7, 122, 10.1016/j.cotox.2018.01.002
Furchgott, 1980, The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine, Nature, 2, 373, 10.1038/288373a0
Ignarro, 1988, Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium-dependent and nitric oxide-elicited vascular smooth muscle relaxation, J Pharmacol Exp Ther, 2, 181
Ferrer-Sueta, 2018, Biochemistry of peroxynitrite and protein tyrosine nitration, Chem Rev, 1, 1338, 10.1021/acs.chemrev.7b00568
Incalza, 2018, Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases, Vascul Pharmacol, 1, 1, 10.1016/j.vph.2017.05.005
Baba, 2018, Role of thiols in oxidative stress, Curr Opin Toxicol, 7, 133, 10.1016/j.cotox.2018.03.005
Hawkins, 2019, Detection, identification, and quantification of oxidative protein modifications, J Biol Chem, 2, 19683, 10.1074/jbc.REV119.006217
Griendling, 2016, Measurement of reactive oxygen species, reactive nitrogen species, and redox-dependent signaling in the cardiovascular system: a scientific statement from the American Heart Association, Circ Res, 1, 39
Skoko, 2019, Signals getting crossed in the entanglement of redox and phosphorylation pathways: phosphorylation of peroxiredoxin proteins sparks cell signaling, Antioxidants (Basel), 8, 29, 10.3390/antiox8020029
Wenzel, 2017, Redox regulation of cardiovascular inflammation—immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species, Free Radic Biol Med, 1, 48, 10.1016/j.freeradbiomed.2017.01.027
Hood, 2016, Nicotinamide adenine dinucleotide phosphate oxidase–mediated redox signaling and vascular remodeling by 16α-hydroxyestrone in human pulmonary artery cells: implications in pulmonary arterial hypertension, Hypertension, 6, 796, 10.1161/HYPERTENSIONAHA.116.07668
Vukelic, 2014, Angiotensin II, from vasoconstrictor to growth factor: a paradigm shift, Circ Res, 1, 754, 10.1161/CIRCRESAHA.114.303045
Ray, 2012, Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling, Cell Signal, 2, 981, 10.1016/j.cellsig.2012.01.008
García-Redondo, 2015, c-Src, ERK1/2 and Rho kinase mediate hydrogen peroxide-induced vascular contraction in hypertension: role of TXA2, NAD(P)H oxidase and mitochondria, J Hypertens, 3, 77, 10.1097/HJH.0000000000000383
Wei, 2014, Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis, J Biol Chem, 2, 31150, 10.1074/jbc.M114.579771
Tabet, 2005, Mitogen-activated protein kinase activation by hydrogen peroxide is mediated through tyrosine kinase–dependent, protein kinase C–independent pathways in vascular smooth muscle cells: upregulation in spontaneously hypertensive rats, J Hypertens, 2, 2005, 10.1097/01.hjh.0000185715.60788.1b
Go, 2011, Cysteine/cystine redox signaling in cardiovascular disease, Free Radic Biol Med, 5, 495, 10.1016/j.freeradbiomed.2010.11.029
Cuello, 2018, Oxidation of cardiac myofilament proteins: priming for dysfunction?, Mol Aspects Med, 6, 47, 10.1016/j.mam.2018.08.003
Paravicini, 2006, Redox signaling in hypertension, Cardiovasc Res, 7, 247, 10.1016/j.cardiores.2006.05.001
Cuadrado, 2018, Transcription factor NRF2 as a therapeutic target for chronic diseases: a systems medicine approach, Pharmacol Rev, 7, 348, 10.1124/pr.117.014753
Brautigan, 2018, Protein serine/threonine phosphatases: keys to unlocking regulators and substrates, Annu Rev Biochem, 8, 921, 10.1146/annurev-biochem-062917-012332
Tabet, 2008, Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR, Circ Res, 1, 149, 10.1161/CIRCRESAHA.108.178608
Tejero, 2019, Sources of vascular nitric oxide and reactive oxygen species and their regulation, Physiol Rev, 9, 311, 10.1152/physrev.00036.2017
Freed, 2017, Communication is key: mechanisms of intercellular signaling in vasodilation, J Cardiovasc Pharmacol, 6, 264, 10.1097/FJC.0000000000000463
Feelisch, 2020, Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling, Cardiovasc Res, 1, 51, 10.1093/cvr/cvz202
Friederich-Persson, 2017, Brown adipose tissue regulates small artery function through NADPH oxidase 4–derived hydrogen peroxide and redox-sensitive protein kinase G-1α, Arterioscler Thromb Vasc Biol, 3, 455, 10.1161/ATVBAHA.116.308659
Kim, 2017, ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis, Am J Physiol Cell Physiol, 3, C749, 10.1152/ajpcell.00346.2016
Knock, 2011, Redox regulation of protein kinases as a modulator of vascular function, Antioxid Redox Signal, 1, 1531, 10.1089/ars.2010.3614
Cameron, 2015, Polarized cell motility induces hydrogen peroxide to inhibit cofilin via cysteine oxidation, Curr Biol, 2, 1520, 10.1016/j.cub.2015.04.020
Dikalov, 2013, Role of mitochondrial oxidative stress in hypertension, Am J Physiol Heart Circ Physiol, 3, H1417, 10.1152/ajpheart.00089.2013
Araujo, 2014, Oxidative stress in hypertension: role of the kidney, Antioxid Redox Signal, 2, 74, 10.1089/ars.2013.5259
Callera, 2006, Endothelin-1–induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase–independent mechanisms, Clin Sci (Lond), 1, 243, 10.1042/CS20050307
Vaka, 2020, Blockade of endogenous angiotensin II type I receptor agonistic autoantibody activity improves mitochondrial reactive oxygen species and hypertension in a rat model of preeclampsia, Am J Physiol Regul Integr Comp Physiol, 3, R256, 10.1152/ajpregu.00179.2019
Sánchez-Aranguren, 2014, Endothelial dysfunction and preeclampsia: role of oxidative stress, Front Physiol, 5, 372, 10.3389/fphys.2014.00372
Lopes, 2015, Downregulation of nuclear factor erythroid 2-related factor and associated antioxidant genes contributes to redox-sensitive vascular dysfunction in hypertension, Hypertension, 6, 1240, 10.1161/HYPERTENSIONAHA.115.06163
Drummond, 2011, Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets, Nat Rev Drug Discov, 1, 453, 10.1038/nrd3403
Cifuentes-Pagano, 2012, NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS, Cell Mol Life Sci, 6, 2315, 10.1007/s00018-012-1009-2
Maksimenko, 2005, Experimental antioxidant biotherapy for protection of the vascular wall by modified forms of superoxide dismutase and catalase, Curr Pharm Des, 1, 2007, 10.2174/1381612054065756
Gomez-Guzman, 2012, Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension, Free Rad Biol Med, 5, 70, 10.1016/j.freeradbiomed.2011.09.015
Touyz, 2017, Redox stress defines the small artery vasculopathy of hypertension: how do we bridge the bench-to-bedside gap?, Circ Res, 1, 1721, 10.1161/CIRCRESAHA.117.310672
Montezano, 2015, Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies, Can J Cardiol, 3, 631, 10.1016/j.cjca.2015.02.008
Ward, 2004, Oxidative stress in human hypertension: association with antihypertensive treatment, gender, nutrition, and lifestyle, Free Radic Biol Med, 3, 226, 10.1016/j.freeradbiomed.2003.10.021
Ghasemzadeh, 2014, Oxidative stress is associated with increased pulmonary artery systolic pressure in humans, Hypertension, 6, 1270, 10.1161/HYPERTENSIONAHA.113.02360
Verma, 2019, Oxidative stress and biomarker of TNF-α, MDA and FRAP in hypertension, J Med Life, 1, 253
Gkaliagkousi, 2018, Asymmetric dimethylarginine levels are associated with augmentation index across naïve untreated patients with different hypertension phenotypes, J Clin Hypertens (Greenwich), 2, 680, 10.1111/jch.13237
Carrizzo, 2013, Resveratrol improves vascular function in patients with hypertension and dyslipidemia by modulating NO metabolism, Hypertension, 6, 359, 10.1161/HYPERTENSIONAHA.111.01009
González, 2014, Essential hypertension and oxidative stress: new insights, World J Cardiol, 6, 353, 10.4330/wjc.v6.i6.353
Touyz, 2005, p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: role in NAD(P)H oxidase regulation by angiotensin II, Arterioscler Thromb Vasc Biol, 2, 512, 10.1161/01.ATV.0000154141.66879.98
Young, 2017, Endoplasmic reticulum stress in the pathogenesis of hypertension, Exp Physiol, 1, 869, 10.1113/EP086274
Santos, 2014, Endoplasmic reticulum stress and Nox-mediated reactive oxygen species signaling in the peripheral vasculature: potential role in hypertension, Antioxid Redox Signal, 20, 121, 10.1089/ars.2013.5262
Rodrigo, 2013, Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage, Dis Markers, 3, 773, 10.1155/2013/974358
Eslami, 2014, Glutathione-S-transferase M1 and T1 null genotypes are associated with hypertension risk: a systematic review and meta-analysis of 12 studies, Curr Hypertens Rep, 1, 43
Wyche, 2004, C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils, Hypertension, 4, 1246, 10.1161/01.HYP.0000126579.50711.62
Rafiq, 2014, C242T polymorphism of the NADPH oxidase p22PHOX gene and its association with endothelial dysfunction in asymptomatic individuals with essential systemic hypertension, Mol Med Rep, 9, 1857, 10.3892/mmr.2014.1992
Kraja, 2017, New blood pressure-associated loci identified in meta-analyses of 475 000 individuals, Circ Cardiovasc Genet, 10, 10.1161/CIRCGENETICS.117.001778
Sylvester, 2019, Sex-specific mechanisms in inflammation and hypertension, Curr Hypertens Rep, 2, 53, 10.1007/s11906-019-0959-2
Ji, 2010, Sex chromosome effects unmasked in Ang II–induced hypertension, Hypertension, 5, 1275, 10.1161/HYPERTENSIONAHA.109.144949
Khan, 2019, Chin-Dusting JPF. Y chromosome, hypertension and cardiovascular disease: is inflammation the answer?, Int J Mol Sci, 20, 2892, 10.3390/ijms20122892
Ojeda, 2014, Sex differences in the developmental programming of hypertension, Acta Physiol (Oxf), 2, 307, 10.1111/apha.12206
Reckelhoff, 2019, Sex, oxidative stress, and hypertension: Insights from animal models, Physiology (Bethesda), 3, 178
Ide, 2002, Greater oxidative stress in healthy young men compared with premenopausal women, Arterioscler Thromb Vasc Biol, 2, 1239
Bhatia, 2012, Oxidative stress contributes to sex differences in angiotensin II–mediated hypertension in spontaneously hypertensive rats, Am J Physiol Regul Integr Comp Physiol, 3, R274, 10.1152/ajpregu.00546.2011
Ji, 2007, Female protection in progressive renal disease is associated with estradiol attenuation of superoxide production, Gend Med, 4, 56, 10.1016/S1550-8579(07)80009-X
Miller, 2007, Effect of gender on NADPH-oxidase activity, expression and function in the cerebral circulation: role of estrogen, Stroke, 3, 2142, 10.1161/STROKEAHA.106.477406
Borras, 2005, 17Beta-oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK-1 and ERK2(MAPK)/NFκB cascade, Aging Cell, 4, 113, 10.1111/j.1474-9726.2005.00151.x
Nguyen Dinh Cat, 2013, Angiotensin II, NADPH oxidase, and redox signaling in the vasculature, Antioxid Redox Signal, 1, 1110, 10.1089/ars.2012.4641
Montezano, 2014, Angiotensin II and vascular injury, Curr Hypertens Rep, 1, 431, 10.1007/s11906-014-0431-2
Guzik, 2017, Oxidative stress, inflammation, and vascular aging in hypertension, Hypertension, 7, 660, 10.1161/HYPERTENSIONAHA.117.07802
Petrie, 2018, Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms, Can J Cardiol, 3, 575, 10.1016/j.cjca.2017.12.005
Masi, 2019, Angiotensin II and vascular damage in hypertension: Role of oxidative stress and sympathetic activation, Vascul Pharmacol, 1, 13, 10.1016/j.vph.2019.01.004
Mattson, 2019, Immune mechanisms of salt-sensitive hypertension and renal end-organ damage, Nat Rev Nephrol, 1, 290, 10.1038/s41581-019-0121-z
Rajagopalan, 2018, Air pollution and cardiovascular disease: JACC state-of-the-art review, J Am Coll Cardiol, 7, 2054, 10.1016/j.jacc.2018.07.099
Rautureau, 2012, Endothelin in hypertension: an update, Curr Opin Nephrol Hypertens, 2, 128, 10.1097/MNH.0b013e32834f0092
Touyz, 2018, Vascular smooth muscle contraction in hypertension, Cardiovasc Res, 1, 529, 10.1093/cvr/cvy023
Lopes, 2020, Crosstalk between vascular redox and calcium signaling in hypertension involves TRPM2 (transient receptor potential melastatin 2) cation channel, Hypertension, 7, 139, 10.1161/HYPERTENSIONAHA.119.13861
Mihalj, 2016, Blood pressure reduction is associated with the changes in oxidative stress and endothelial activation in hypertension, regardless of antihypertensive therapy, Kidney Blood Press Res, 4, 721, 10.1159/000450562
Xu, 2009, Endothelial cells negatively modulate reactive oxygen species generation in vascular smooth muscle cells: role of thioredoxin, Hypertension, 5, 427, 10.1161/HYPERTENSIONAHA.109.133983
Dikalov, 2014, Nox2-induced production of mitochondrial superoxide in angiotensin II–mediated endothelial oxidative stress and hypertension, Antioxid Redox Signal, 2, 281, 10.1089/ars.2012.4918
Coelho, 2018, Three-month endothelial human endothelin-1 overexpression causes blood pressure elevation and vascular and kidney injury, Hypertension, 7, 208, 10.1161/HYPERTENSIONAHA.117.09925
Tsai, 2017, Enhanced endothelin-1/Rho-kinase signalling and coronary microvascular dysfunction in hypertensive myocardial hypertrophy, Cardiovasc Res, 1, 1329, 10.1093/cvr/cvx103
Colafella KM, Neves KB, Montezano AC, et al. Selective ETA versus dual ETA/B receptor blockade for the prevention of sunitinib-induced hypertension and albuminuria in WKY rats [e-pub ahead of print]. Cardiovasc Res.
Ganesh, 2016, Impact of superoxide dismutase mimetic AEOL 10150 on the endothelin system of Fischer 344 rats, PLoS One, 1
du Plooy, 2017, The association of endothelin-1 with markers of oxidative stress in a biethnic South African cohort: the SABPA study, Hypertens Res, 4, 189, 10.1038/hr.2016.128
Fernandez-Patron, 2007, Therapeutic potential of the epidermal growth factor receptor transactivation in hypertension: a convergent signaling pathway of vascular tone, oxidative stress, and hypertrophic growth downstream of vasoactive G-protein–coupled receptors?, Can J Physiol Pharmacol, 8, 97, 10.1139/y06-097
Forrester, 2018, Angiotensin II signal transduction: an update on mechanisms of physiology and pathophysiology, Physiol Rev, 9, 1627, 10.1152/physrev.00038.2017
Neves, 2018, VEGFR (vascular endothelial growth factor receptor) inhibition induces cardiovascular damage via redox-sensitive processes, Hypertension, 7, 638, 10.1161/HYPERTENSIONAHA.117.10490
Li, 2010, Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR, Am J Physiol Heart Circ Physiol, 2, H1959, 10.1152/ajpheart.00526.2010
Cruzado, 2005, Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: effect of angiotensin II and role of insulinlike growth factor-1 receptor transactivation, Am J Hypertens, 1, 81, 10.1016/j.amjhyper.2004.09.001
Touyz, 2003, Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation, Can J Physiol Pharmacol, 8, 159, 10.1139/y02-164
Touyz, 2002, Increased angiotensin II–mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats, Hypertension, 3, 479, 10.1161/hy02t2.102909
Dinh, 2017, Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress, Aging (Albany NY), 9, 1595, 10.18632/aging.101255
Zahradka, 2004, Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinase, Endocrinology, 1, 2978, 10.1210/en.2004-0029
Montezano, 2015, Redox signaling, Nox5 and vascular remodeling in hypertension, Curr Opin Nephrol Hypertens, 2, 425, 10.1097/MNH.0000000000000153
Pantelidis, 2018, The mechanisms of actions of aldosterone and its antagonists in cardiovascular disease, Curr Pharm Des, 2, 5491
Cannavo, 2018, Aldosterone and mineralocorticoid receptor system in cardiovascular physiology and pathophysiology, Oxid Med Cell Longev, 20, 1204598
Chou, 2018, IL-6 trans-signalling contributes to aldosterone-induced cardiac fibrosis, Cardiovasc Res, 1, 690, 10.1093/cvr/cvy013
Rossi, 2019, Primary aldosteronism: JACC state-of-the-art review, J Am Coll Cardiol, 7, 2799, 10.1016/j.jacc.2019.09.057
Kawarazaki, 2016, The role of aldosterone in obesity-related hypertension, Am J Hypertens, 2, 415, 10.1093/ajh/hpw003
Virdis, 2002, Spironolactone improves angiotensin-induced vascular changes and oxidative stress, Hypertension, 4, 504, 10.1161/01.HYP.0000034738.79310.06
Beswick, 2001, NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat, Hypertension, 3, 1107, 10.1161/hy1101.093423
McCurley, 2012, Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors, Nat Med, 1, 1429, 10.1038/nm.2891
Briet, 2016, Aldosterone-induced vascular remodeling and endothelial dysfunction require functional angiotensin type 1a receptors, Hypertension, 6, 897, 10.1161/HYPERTENSIONAHA.115.07074
Montezano, 2008, Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src–regulated redox-sensitive RhoA pathways, Arterioscler Thromb Vasc Biol, 2, 1511, 10.1161/ATVBAHA.108.168021
Fan, 2008, Synergy of aldosterone and high salt induces vascular smooth muscle hypertrophy through up-regulation of NOX1, J Steroid Biochem Mol Biol, 1, 29, 10.1016/j.jsbmb.2008.02.012
Iwashima, 2008, Aldosterone induces superoxide generation via Rac1 activation in endothelial cells, Endocrinology, 1, 1009, 10.1210/en.2007-0864
Harvey, 2017, Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone–mineralocorticoid receptor–Nox1 axis, Life Sci, 1, 110, 10.1016/j.lfs.2017.05.002
Hashikabe, 2006, Aldosterone impairs vascular endothelial cell function, J Cardiovasc Pharmacol, 4, 609, 10.1097/01.fjc.0000211738.63207.c3
Callera, 2005, c-Src–dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats, Hypertension, 4, 1032, 10.1161/01.HYP.0000176588.51027.35
Rautureau, 2011, Cross-talk between aldosterone and angiotensin signaling in vascular smooth muscle cells, Steroids, 7, 834
Cannavo, 2016, Myocardial pathology induced by aldosterone is dependent on noncanonical activities of G protein-coupled receptor kinases, Nat Commun, 7, 10877, 10.1038/ncomms10877
Silva, 2015, Spironolactone treatment attenuates vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling, Front Physiol, 6, 269, 10.3389/fphys.2015.00269
Nguyen Dinh Cat, 2010, The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure, FASEB J, 2, 2454
Favre, 2011, Coronary endothelial dysfunction after cardiomyocyte-specific mineralocorticoid receptor overexpression, Am J Physiol Heart Circ Physiol, 3, H2035, 10.1152/ajpheart.00552.2010
Ahokas, 2003, Aldosteronism and peripheral blood mononuclear cell activation: a neuroendocrine-immune interface, Circ Res, 9, e124
Bienvenu, 2012, Macrophage mineralocorticoid receptor signaling plays a key role in aldosterone-independent cardiac fibrosis, Endocrinology, 1, 3416, 10.1210/en.2011-2098
Hirata, 2012, Contribution of glucocorticoid-mineralocorticoid receptor pathway on the obesity-related adipocyte dysfunction, Biochem Biophys Res Commun, 4, 182, 10.1016/j.bbrc.2012.01.139
Ross, 1993, The pathogenesis of atherosclerosis: a perspective for the 1990, Nature, 3, 801, 10.1038/362801a0
Barrows, 2019, Inflammation, immunity, and oxidative stress in hypertension—partners in crime?, Adv Chronic Kidney Dis, 2, 122, 10.1053/j.ackd.2019.03.001
Tomiyama, 2017, The contribution of inflammation to the development of hypertension mediated by increased arterial stiffness, J Am Heart Assoc, 6
Carbone, 2019, Baseline hs-CRP predicts hypertension remission in metabolic syndrome, Eur J Clin Invest, 4, e13128, 10.1111/eci.13128
Schüler, 2019, T cell–derived IL-17A induces vascular dysfunction via perivascular fibrosis formation and dysregulation of •NO/cGMP signaling, Oxid Med Cell Longev, 20, 6721531
Burger, 2011, Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/Rho kinase pathways targeted to lipid rafts, Arterioscler Thromb Vasc Biol, 3, 1898, 10.1161/ATVBAHA.110.222703
Schiffrin, 2015, Mechanisms of remodeling of small arteries, antihypertensive therapy and the immune system in hypertension, Clin Invest Med, 3, 394, 10.25011/cim.v38i6.26202
Harijith, 2014, Reactive oxygen species at the crossroads of inflammasome and inflammation, Front Physiol, 5, 10.3389/fphys.2014.00352
Pasqua, 2018, Role of NLRP 3 inflammasome in hypertension: A potential therapeutic target, Curr Pharm Biotechnol, 1, 708, 10.2174/1389201019666180808162011
Zhong, 2013, TRPM2 links oxidative stress to NLRP3 inflammasome activation, Nat Commun, 4, 1611, 10.1038/ncomms2608
Zhang, 2019, NLRP3 inflammasome is involved in calcium-sensing receptor–induced aortic remodeling in SHRs, Mediators Inflamm, 20, 6847087
Villegas, 2013, Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome, Antioxid Redox Signal, 1, 1753, 10.1089/ars.2012.4799
Ferreira, 2019, NLRP3 inflammasome and mineralocorticoid receptors are associated with vascular dysfunction in type 2 diabetes mellitus, Cells, 8, 1595, 10.3390/cells8121595
Guzik, 2007, Role of the T cell in the genesis of angiotensin ii induced hypertension and vascular dysfunction, J Exp Med, 2, 2449, 10.1084/jem.20070657
de Ciuceis, 2005, Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin II–infused macrophage colony–stimulating factor–deficient mice: evidence for a role in inflammation in angiotensin-induced vascular injury, Arterioscler Thromb Vasc Biol, 2, 2106, 10.1161/01.ATV.0000181743.28028.57
Wenzel, 2019, Monocytes as immune targets in arterial hypertension, Br J Pharmacol, 1, 1966, 10.1111/bph.14389
Radi, 2018, Oxygen radicals, nitric oxide, and peroxynitrite: redox pathways in molecular medicine, Proc Natl Acad Sci U S A, 1, 5839, 10.1073/pnas.1804932115
Carracedo, 2018, Protein carbamylation: a marker reflecting increased age-related cell oxidation, Int J Mol Sci, 19, 1495, 10.3390/ijms19051495
Sheehan, 2019, The clinical potential of thiol redox proteomics, Expert Rev Proteomics, 2, 1