Overview: Global and Local Impact of Antibiotic Resistance

Centers for Disease Control and Prevention. Antibiotic resistance threats in the United States. 2013. Available at: http://www.cdc.gov/drugresistance/threat-report-2013/pdf/ar-threats-2013-508.pdf. Accessed March 3, 2016.

Livermore, 2012, Current epidemiology and growing resistance of gram-negative pathogens, Korean J Intern Med, 27, 128, 10.3904/kjim.2012.27.2.128

National Institute of Allergy and Infectious Diseases. NIAID’s Antibacterial resistance program: current status and future directions. 2014. Available at: http://www.niaid.nih.gov/topics/antimicrobialResistance/documents/arstrategicplan2014.pdf. Accessed March 3, 2016.

Katz, 2006, Where have all the antibiotic patents gone?, Nat Biotechnol, 24, 1529, 10.1038/nbt1206-1529

Hersh, 2012, Unmet medical need in infectious diseases, Clin Infect Dis, 54, 1677, 10.1093/cid/cis275

Shlaes, 2013, The FDA reboot of antibiotic development, Antimicrobial Agents Chemother, 57, 4605, 10.1128/AAC.01277-13

Payne, 2007, Drugs for bad bugs: confronting the challenges of antibiotic discovery, Nat Rev Drug Discov, 6, 29, 10.1038/nrd2201

Obama, 2014, 1

Vasoo, 2015, Emerging issues in gram-negative bacterial resistance: an update for the practicing clinician, Mayo Clin Proc, 90, 395, 10.1016/j.mayocp.2014.12.002

Tzouvelekis, 2012, Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions, Clin Microbiol Rev, 25, 682, 10.1128/CMR.05035-11

Hall, 2005, Revised Ambler classification of beta-lactamases, J Antimicrob Chemother, 55, 1050, 10.1093/jac/dki130

Potron, 2015, Emerging broad-spectrum resistance to Pseudomonas aeruginosa and Acinetobacter baumannii: mechanisms and epidemiology, Int J Antimicrob Agents, 45, 568, 10.1016/j.ijantimicag.2015.03.001

Davies, 2010, Origins and evolution of antibiotic resistance, Microbiol Mol Biol Rev, 77, 417, 10.1128/MMBR.00016-10

Aminov, 2010, A brief history of the antibiotic era: lessons learned and challenges for the future, Front Microbiol, 1, 134, 10.3389/fmicb.2010.00134

Tang, 2014, Mechanisms of β-lactam antimicrobial resistance and epidemiology of major community- and healthcare-associated multidrug-resistant bacteria, Adv Drug Deliv Rev, 78, 3, 10.1016/j.addr.2014.08.003

Fonseca, 2015, The complex evolution of antibiotic resistance in Mycobacterium tuberculosis, Int J Infect Dis, 32, 94, 10.1016/j.ijid.2015.01.014

Deutschendorf, 2012, Previous use of quinolones: a surrogate marker for first line anti-tuberculosis drugs resistance in HIV-infected patients?, Braz J Infect Dis, 16, 142

Kariuki, 2010, Typhoid in Kenya is associated with a dominant multidrug-resistant Salmonella enterica serovar Typhi haplotype that is also widespread in Southeast Asia, J Clin Microbiol, 48, 2171, 10.1128/JCM.01983-09

Baker, 2015, A return to the pre-antimicrobial era?, Science, 347, 1064, 10.1126/science.aaa2868

Koirala, 2012, Highly resistant Salmonella enterica serovar Typhi with a novel gyrA mutation raises questions about the long-term efficacy of older fluoroquinolones for treating typhoid fever, Antimicrob Agents Chemother, 56, 2761, 10.1128/AAC.06414-11

Berendonk, 2015, Tackling antibiotic resistance: the environmental framework, Nat Rev Microbiol, 13, 310, 10.1038/nrmicro3439

Amos, 2014, Waste water effluent contributes to the dissemination of CTX-M-15 in the natural environment, J Antimicrob Chemother, 69, 1785, 10.1093/jac/dku079

Hollis, 2013, Preserving antibiotics, rationally, N Engl J Med, 369, 2474, 10.1056/NEJMp1311479

Chang, 2015, Antibiotics in agriculture and the risk to human health: how worried should we be?, Evol Appl, 8, 240, 10.1111/eva.12185

Travers, 2002, Morbidity of infections caused by antimicrobial-resistant bacteria, Clin Infect Dis, 34, S131, 10.1086/340251

Brunelle, 2015, Chloramphenicol and tetracycline decrease motility and increase invasion and attachment gene expression in specific isolates of multi-drug resistant Salomella enterica serovar Typhimurium, Front Microbiol, 5, 801, 10.3389/fmicb.2014.00801

Van der Mee-Marquet, 2011, Emergence of unusual bloodstream infections associated with pig-borne-like Staphylococcus aureus ST398 in France, Clin Infect Dis, 52, 152, 10.1093/cid/ciq053

Lebreton, 2013, Emergence of epidemic multi-drug-resistant Enterococcus faecium from animal and commensal strains, MBio, 4, 10.1128/mBio.00534-13

Reich, 2013, Extended-spectrum β-lactamase- and AmpC-producing enterobacteria in healthy broiler chickens, Germany, Emerg Infect Dis, 19, 1253, 10.3201/eid1908.120879

Wang, 2012, Identification of New Delhi metallo-β-lactamase 1 in Acinetobacter lwoffii of food animal origin, PLoS One, 7, e37152, 10.1371/journal.pone.0037152

Nannapaneni, 2009, Ciprofloxacin-resistant Campylobacter persists in raw retail chicken after the fluoroquinolone ban, Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 26, 1348, 10.1080/02652030903013294

Smith, 2013, The true cost of antimicrobial resistance, BMJ, 346, f1493, 10.1136/bmj.f1493

Lee, 2006, Impact of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species on clinical outcomes and hospital costs: a matched cohort study, Infect Control Hosp Epidemiol, 27, 1226, 10.1086/507962

Walsh, 2011, Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study, Lancet Infect Dis, 11, 355, 10.1016/S1473-3099(11)70059-7

World Health Organization, 2014

Antonanzas, 2015, Economic features of antibiotic resistance: the case of methicillin-resistant Staphylococcus aureus, Pharmacoeconomics, 33, 285, 10.1007/s40273-014-0242-y

Bergman, 2004, Effect of macrolide consumption on erythromycin resistance in Streptococcus pyogenes in Finland in 1997-2001, Clin Infect Dis, 38, 1251, 10.1086/383309

Livermore, 2014, Of stewardship, motherhood and apple pie, Int J Antimicrob Agents, 43, 319, 10.1016/j.ijantimicag.2014.01.011

Nilholm, 2015, An audit-based, infectious disease specialist-guided antimicrobial stewardship program profoundly reduced antibiotic use without negatively affecting patient outcomes, Open Forum Infect Dis, 2, ofv042, 10.1093/ofid/ofv042

Claret, 2015, The world alliance against antibiotic resistance: consensus for a declaration, Clin Infect Dis, 60, 1837, 10.1093/cid/civ196

Morrissey, 2013, A review of ten years of study for monitoring antimicrobial resistance trends (SMART) from 2002 to 2011, Pharmaceuticals (Basel), 6, 1335, 10.3390/ph6111335

World Health Organization, 2015