Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression

Bachoo, 2001, Malignant glioma: genetics and biology of a grave matter, Genes Dev, 15, 1311, 10.1101/gad.891601

Cavenee, 2002, The WHO classification of tumors of the nervous system, J Neuropathol Exp Neurol, 61, 215, 10.1093/jnen/61.3.215

Rosado, 2015, Functional and physiopathological implications of TRP channels, Biochim Biophys Acta, 1853, 1772, 10.1016/j.bbamcr.2015.04.016

Montell, 2007, TRP channels, Annu Rev Biochem, 76, 387, 10.1146/annurev.biochem.75.103004.142819

Owsianik, 2011, The transient receptor potential family of ion channels, Genome Biol, 12, 218, 10.1186/gb-2011-12-3-218

Slaugenhaupt, 2000, Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel, Hum Mol Genet, 9, 2471, 10.1093/hmg/9.17.2471

Xu, 2010, Mucolipins: intracellular TRPML-1-3 Channels, FEBS Letter, 584, 2013, 10.1016/j.febslet.2009.12.056

García-Añoveros, 2011, Expression and vesicular localization of mouse Trpml3 in stria vascularis, hair cells, and vomeronasal and olfactory receptor neurons, J Comp Neurol, 519, 1095, 10.1002/cne.22554

García-Añoveros, 2011, TRPML2 and the evolution of mucolipins, Adv Exp Med Biol, 704, 221, 10.1007/978-94-007-0265-3_12

Wiwatpanit, 2014, TRPML2 and mucolipin evolution, Handb Exp Pharmacol, 222, 647, 10.1007/978-3-642-54215-2_25

Holden, 2010, Mucolipidosis Type IV: a subtle pediatric neurodegenerative disorder, Pediatr Neurol, 42, 223, 10.1016/j.pediatrneurol.2009.10.002

Noben-Trauth, 2002, Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice, Proc Natl Acad Sci U S A, 99, 14994, 10.1073/pnas.222425399

Kiselyov, 2009, TRPMLs: in sickness and in health, Am J Physiol Renal Physiol, 296, 1245, 10.1152/ajprenal.90522.2008

Puertollano, 2015, Novel Role of TRPML2 in the Regulation of the Innate Immune Response, J Immunol, 195, 4922, 10.4049/jimmunol.1500163

Xu, 2010, PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome, Nat Commun, 1, 38, 10.1038/ncomms1037

Montell, 2006, Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1, J Biol Chem, 281, 17517, 10.1074/jbc.M600807200

Heller, 2012, Constitutive activity of TRPML-2 and TRPML-3 Channels versus Activation by Low Extracellular sodium and small molecules, JBC, 287, 22701, 10.1074/jbc.M112.369876

Puertollano, 2007, Mucolipidin-2 localizes to the Arf-6-associated pathway and regulates recycling of GPI-APs, Traffic, 8, 1404, 10.1111/j.1600-0854.2007.00619.x

Minke, 2010, Constitutive activity of the human TRPML-2 Channel induces Cell Degeneration, JBC, 285, 2771, 10.1074/jbc.M109.046508

Chuang, 2013, Concurrent gene signature for han Chinese breast cancers, PLoS One, 8, e76421, 10.1371/journal.pone.0076421

Lee, 2008, Role of hyaluronan in glioma invasion, Cell Adh Migr, 2, 202, 10.4161/cam.2.3.6320

Meijer, 2005, Autophagy and signaling: their role in cell survival and cell death, Cell Death Differ, 12, 1509, 10.1038/sj.cdd.4401751

Amantini, 2011, TRPV channels in tumor growth and progression, Adv Exp Med Biol, 704, 947, 10.1007/978-94-007-0265-3_49

Ghosh, 2011, GLIOMA exploring its biology and practical relevance, 163, 10.5772/880

Camci, 2015, Gene expressions of TRP channels in glioblastoma multiforme and relation with survival, Tumour Biol, 1

Cuajungco, 2015, PAX5 is the transcriptional activator of mucolipidin-2 (MCOLN2) gene, Gene, 555, 194, 10.1016/j.gene.2014.11.003

Gruss, 1995, PAX5 expression correlates with increasing malignancy in human astrocytoma, Clin Cancer Res, 1, 207

Eccles, 2003, Paired-box genes are frequently express in cancer and often required for cancer cell survival, Oncogene, 22, 7989, 10.1038/sj.onc.1206766

Macfarlane, 2014, Increased paired box transcription factor 8 has a survival function in glioma, BMC Cancer, 14, 159, 10.1186/1471-2407-14-159

Brenman, 2015, The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase, Biochem J, 470, 331, 10.1042/BJ20150219

Muallem, 2009, The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy, Traffic, 10, 1157, 10.1111/j.1600-0854.2009.00924.x

Bach, 2010, Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy, J Cell Sci, 123, 3112, 10.1242/jcs.067330

Constantin, 2015, Plasma membrane calcium channels in cancer: Alterations and consequences for cell proliferation and migration, Biochim Biophys Acta, 1848, 2512, 10.1016/j.bbamem.2015.06.009

Stokoe, 1998, Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC, Curr Biol, 8, 1195, 10.1016/S0960-9822(07)00493-9

Baranska, 2004, Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3-kinase signalling and cell proliferation in serum-deprived and nonstarved glioma C6 cells, Br J Pharmacol, 141, 497, 10.1038/sj.bjp.0705639

Georgescu, 2010, Invasive glioblastoma cells acquire stemness and increased Akt activation, Neoplasia, 12, 453, 10.1593/neo.10126

Moelling, 1999, Phosphorylation and regulation of Raf by Akt (protein kinase B), Science, 286, 1741, 10.1126/science.286.5445.1741

Zhu, 2014, Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane, J Biol Chem, 289, 4262, 10.1074/jbc.M113.506501

Meŕida, 1999, The identification of phosphatidylinositol 3,5-bisphosphate in T-lymphocytes and its regulation by interleukin-2, J Biol Chem, 274, 18407, 10.1074/jbc.274.26.18407

Shisheva, 2005, Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway, J Biol Chem, 280, 7883, 10.1074/jbc.M412729200

Xu, 2012, Phosphoinositide isoforms determine compartment-specific ion channel activity, Proc Natl Acad Sci U S A, 109, 11384, 10.1073/pnas.1202194109

Rogister, 2013, Glioblastoma-initiating cells: relationship with neural stem cells and the micro-environment, Cancers (Basel), 5, 1049, 10.3390/cancers5031049

Siegal, 2015, Clinic impact of molecular biomarkers in gliomas, J Clin Neurosci, 22, 437, 10.1016/j.jocn.2014.10.004

Ellis, 1991, Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up, Histopathology, 19, 403, 10.1111/j.1365-2559.1991.tb00229.x

Perez, 2007, American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer, Arch Pathol Lab Med, 131, 18, 10.5858/2007-131-18-ASOCCO