Nội dung được dịch bởi AI, chỉ mang tính chất tham khảo
Vượt qua COVID-19 ở Trung Quốc bất chấp những thiếu sót của hệ thống y tế công cộng: Chúng ta có thể học hỏi gì?
Tóm tắt
Đại dịch COVID-19 bắt đầu ở Vũ Hán, Trung Quốc, vào tháng 12 năm 2019. Mặc dù có một số hoài nghi về việc báo cáo các trường hợp và số ca tử vong ở Trung Quốc, nhưng dường như quốc gia này đã kiểm soát dịch bệnh hiệu quả hơn nhiều quốc gia khác. Trong bài báo này, chúng tôi muốn phân tích các biện pháp đã được thực hiện ở Trung Quốc và so sánh với các quốc gia khác nhằm tìm hiểu những gì họ có thể học hỏi từ Trung Quốc. Chúng tôi phát triển một mô hình động lực học hệ thống của đại dịch COVID-19 ở Vũ Hán. Dựa trên một số mô phỏng, chúng tôi phân tích tác động của việc thay đổi các tham số, chẳng hạn như tỷ lệ tiếp xúc, đến sự phát triển của làn sóng thứ hai. Mặc dù hệ thống y tế của Trung Quốc dường như bị tài chính kém và không hiệu quả, nhưng dịch bệnh đã được kiểm soát trong một khoảng thời gian tương đối ngắn và không có làn sóng thứ hai nào xảy ra ở Vũ Hán cho đến hôm nay. Các biện pháp nhằm kiềm chế dịch bệnh không khác biệt so với những gì đã được thực hiện ở các quốc gia khác, nhưng Trung Quốc đã áp dụng chúng rất sớm và nghiêm ngặt. Ví dụ, việc triển khai mã sức khỏe và công nghệ theo dõi tiếp xúc một cách quyết liệt đã giúp kiềm chế bệnh dịch và ngăn ngừa hiệu quả các làn sóng thứ hai và thứ ba. Thành công của Trung Quốc trong cuộc chiến chống COVID-19 dựa trên việc thực hiện rất nghiêm ngặt một loạt các biện pháp, bao gồm quản lý kỹ thuật số. Trong khi các quốc gia khác bàn luận về việc nới lỏng chế độ phong tỏa ở tỷ lệ 50 trên 100.000 dân, Trung Quốc đã bắt đầu phong tỏa cục bộ với tỷ lệ 3 trên 100.000. Chúng tôi kêu gọi một cuộc tranh luận công khai về việc liệu chính sách này có khả thi cho các quốc gia tự do hơn hay không.
Từ khóa
#COVID-19 #Trung Quốc #hệ thống y tế #biện pháp kiểm soát dịch bệnh #phong tỏa #mô hình động lực họcTài liệu tham khảo
Li Q, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus–infected pneumonia. N Engl J Med. 2020;382:1199.
Zhu N, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–33. https://doi.org/10.1056/NEJMoa2001017.
Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395(10224):565–74. https://doi.org/10.1016/S0140-6736(20)30251-8.
Wu F, Zhao S, Yu B, Chen YM, Wang W, Song ZG, et al. A new coronavirus associated with human respiratory disease in China. Nature. 2020;579(7798):265–9. https://doi.org/10.1038/s41586-020-2008-3.
Zhou P, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579(7798):270–3.
Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020;395(10223):470–3. https://doi.org/10.1016/S0140-6736(20)30185-9.
Pan Y, Zhang D, Yang P, Poon LLM, Wang Q. Viral load of SARS-CoV-2 in clinical samples. Lancet Infect Dis. 2020;20(4):411–2. https://doi.org/10.1016/S1473-3099(20)30113-4.
Lu H, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan, China: the mystery and the miracle. J Med Virol. 2020;92(4):401–2. https://doi.org/10.1002/jmv.25678.
Sohrabi C, Alsafi Z, O'Neill N, Khan M, Kerwan A, al-Jabir A, et al. World Health Organization declares global emergency: a review of the 2019 novel coronavirus (COVID-19). Int J Surg. 2020;76:71–6. https://doi.org/10.1016/j.ijsu.2020.02.034.
John Hopkins University. COVID-19 Dashboard by the Center for Systems Science and Engineering (CSSE). 2021 [cited 2021 10.02.2021]; Available from: https://bit.ly/2PpTa7F.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506. https://doi.org/10.1016/S0140-6736(20)30183-5.
State Council. China’s actions to fight against the COVID-19 epidemic (White Paper). 2020 [cited 2020 13.12.2020]; Available from: http://www.scio.gov.cn/ztk/dtzt/42313/43142/index.htm.
WHO. Listings of WHO’S response to COVID-19. 2020 [cited 2021 03.03.2021]; Available from: https://www.who.int/news/item/29-06-2020-covidtimeline.
Wuhan Municipal Health Commission. Report of Wuhan Municipal Health Commission on viral pneumonia of unknown cause. 2021 [cited 2021 03.03.2021]; Available from: http://www.nhc.gov.cn/xcs/yqtb/202001/1beb46f061704372b7ca41ef3e682229.shtml.
Prevention, C.C.f.D.C.a. Epidemic update and risk assessment of 2019 Novel Coronavirus. 2020 [cited 2021 03.03.2021]; Available from: http://www.chinacdc.cn/jkzt/crb/zl/szkb_11803/jszl_11811/202001/P020200128523354919292.pdf.
Information Office. Diverse press conferences on the prevention and control of Novel Coronavirus Infected Pneumonia epidemic. 2020 [cited 2021 03.03.2021]; Available from: http://www.hubei.gov.cn/hbfb/xwfbh/202001/t20200123_2014594.shtml, http://www.scio.gov.cn/xwfbh/xwbfbh/wqfbh/42311/42470/wz42472/Document/1672422/1672422.htm, http://www.hubei.gov.cn/hbfb/xwfbh/202002/t20200202_2018245.shtml, http://www.hubei.gov.cn/hbfb/xwfbh/202002/t20200206_2019986.shtml, http://www.hubei.gov.cn/hbfb/xwfbh/202002/t20200207_2021401.shtml.
Ministry of Transport. Regular press conference in January 2020. 2020 [cited 2021 03.03.2021]; Available from: http://xxgk.mot.gov.cn/2020/jigou/zcyjs/202006/t20200623_3307524.html.
Hubei Province. The Information Office of the People's Government of Hubei Province holds a press conference on the prevention of pneumonia caused by the new coronavirus. 2020 [cited 2020 13.12.2020]; Available from: www.chinanews.com.
Chen S, Yang J, Yang W, Wang C, Bärnighausen T. COVID-19 control in China during mass population movements at new year. Lancet. 2020;395(10226):764–6. https://doi.org/10.1016/S0140-6736(20)30421-9.
Kraemer MU, et al. The effect of human mobility and control measures on the COVID-19 epidemic in China. Science. 2020;368(6490):493–7. https://doi.org/10.1126/science.abb4218.
Wuhan. Announcement from Wuhan headquarters for Novel Coronavirus Infected Pneumonia epidemic prevention and control (No.1). 23.01.2020. 2020 [cited 2021 03.03.2021]; Available from: http://www.gov.cn/xinwen/2020-01/23/content_5471751.htm.
State Council. Press conference on the progress of epidemic prevention and control and medical treatment under the guidance of the Central Steering Group, 15.02.2020. 2020 [cited 2021 10.02.2021]; Available from: www.china.com.cn.
State Council. Press conference on the latest progress of epidemic prevention and control and measures of caring for medical staff, 14.02.2020. 2020 [cited 2020 15.12.2020 ]; Available from: http://www.scio.gov.cn/xwfbh/xwbfbh/wqfbh/42311/42512/index.htm.
State Council. Press conference on the joint prevention and control of Novel Coronavirus Infected Pneumonia epidemic. 26.01.2020. 2020 [cited 2021 03.03.2021]; Available from: http://www.scio.gov.cn/xwfbh/xwbfbh/wqfbh/42311/42478/index.htm.
Liu, Z. Makeshift hospitals, Wuhan's extraordinary move to fight against epidemic situation, 21.02.2020. 2020 [cited 2021 03.03.2021]; Available from: http://www.jkb.com.cn/news/industryNews/2020/0221/470980.html.
Wuhan Local Records Office. The largest makeshift hospital completed in 6 days in Wuhan. 24.02.2020. 2020 [cited 2021 03.03.2021]; Available from: http://dfzold.wuhan.gov.cn/html/wh2019/lishimingcheng/wuhanzhizui/2020/0224/53959.shtml.
Tian H, Liu Y, Li Y, Wu CH, Chen B, Kraemer MUG, et al. An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China. Science. 2020;368(6491):638–42. https://doi.org/10.1126/science.abb6105.
Wuhan Municipal Health Commission. Official website of Wuhan Municipal Health Commission , Health Commission of Hubei Province. 2021 [cited 2021 10.02.2021]; Available from: www.people.com.cn.
Hangzhou Municipal Health Commission. Hangzhou health code. 2021 [cited 2021 11.02.2021]; Available from: http://wsjkw.hangzhou.gov.cn.
Buder F, Hitzenbichler F, Ehrenstein B, Salzberger B. Der Ausbruch von COVID-19 in China. Internist. 2020;61(8):776–81. https://doi.org/10.1007/s00108-020-00833-w.
Wuhan Municipal Health Commission. Official website of Wuhan Municipal Health Commission, Health Commission of Hubei Province. 2021. [cited 2021 10.02.2021]; Available from: https://www.people.com.cn.
National Health Commission of China. COVID-19 Prevention and Control Plan (Seventh Edition). 2020 [cited 2020 16.12.2020]; Available from: http://www.nhc.gov.cn/jkj/s3577/202009/318683cbfaee4191aee29cd774b19d8d/files/f9ea38ce2c2d4352bf61ab0feada439f.pdf.
National Health Commission of China. Press conference of National Health Commission of China. 2020 [cited 2020 16.12.2020]; Available from: http://www.gov.cn/xinwen/gwylflkjz122/index.htm.
News, C. An update on COVID-19 risk areas in China. China News 2021 [cited 2021 10.02.2021]; Available from: www.chinanews.com.
Cyranoski D. When will the coronavirus outbreak peak? Nature. 2020.
Liu, J. and Y. Zhao. Coronavirus Is Likely to Become a Seasonal Infection Like the Flu, Top Chinese Scientists Warn. 2020 [cited 2021 10.02.2021]; Available from: https://time.com/5828325/coronavirus-covid19-seasonal-asymptomatic-carriers/.
En'Ko P. On the course of epidemics of some infectious diseases. Int J Epidemiol. 1989;18(4):749–55. https://doi.org/10.1093/ije/18.4.749.
Macdonald G. The epidemiology and control of malaria. Oxford: Oxford University Press; 1957.
Beck JR, Pauker SG. The Markov process in medical prognosis. Med Decis Mak. 1983;3(4):419–58. https://doi.org/10.1177/0272989X8300300403.
Fleßa S, Greiner W, editors. Grundlagen der Gesundheitsökonomie: eine Einführung in das wirtschaftliche Denken im Gesundheitswesen. 3 ed. Berlin, Heidelberg: Springer Gabler; 2020.
Forrester JW. Industrial dynamics. Cambridge: Wright Allen Press; 1964.
Forrester JW. World dynamics. Cambridge: Wright-Allen Press; 1971.
Alfeld LE. Urban dynamics—the first fifty years. Syst Dyn Rev. 1995;11(3):199–217. https://doi.org/10.1002/sdr.4260110303.
Flessa S. Malaria und Aids. Gesundheitsökonomische Analysen auf Grundlage von Disease Dynamics Modellen. Lage: Jacobs Verlag; 2002.
Sterman J. Business Dynamics. Boston: McGraw-Hill; 2016.
Flessa S, Dietz D, Weiderpass E. Health policy support under extreme uncertainty: the case of cervical cancer in Cambodia. EURO J Decis Processes. 2016;4(3–4):183–218. https://doi.org/10.1007/s40070-015-0053-1.
Bernal-García, S., et al. A new system dynamics model of climate and malaria incidence in Colombia. in second international & interdisciplinary workshop on mathematical modeling, ecology, evolution and dynamics of dengue and related diseases (IIWEE). 2015.
Dangerfield B. System dynamics applications to European health care issues. J Oper Res Soc. 1999;50(4):345–53. https://doi.org/10.1057/palgrave.jors.2600729.
Rauner MS, Brailsford SC, Flessa S. Use of discrete-event simulation to evaluate strategies for the prevention of mother-to-child transmission of HIV in developing countries. J Oper Res Soc. 2005;56(2):222–33. https://doi.org/10.1057/palgrave.jors.2601884.
Claus F. Gesamtwirtschaftliche Analyse eines prästationären MRSA-Screenings. Berlin, Heidelberg: Springer; 2021. https://doi.org/10.1007/978-3-658-32543-5.
Wegmaier P. Möglichkeiten und Grenzen der Covid-19-Modellierung. Monitor Versorgungsforschung. 2021;14(2):22–6.
Ioannidis JP, Cripps S, Tanner MA. Forecasting for COVID-19 has failed. Int J Forecast. 2020. https://doi.org/10.1016/j.ijforecast.2020.08.004.
Huntington HG, Weyant JP, Scweeney JL. Modelling for insights, not numbers: the experience of the energy modelling forum, OMEGA. Int J Manage Sci. 1982;10(5):449–62. https://doi.org/10.1016/0305-0483(82)90002-0.
Wang M, Flessa S. Modelling Covid-19 under uncertainty: what can we expect? Eur J Health Econ. 2020;21(5):665–8. https://doi.org/10.1007/s10198-020-01202-y.
Arumugam R, Rajathi M. A Markov model for prediction of Corona virus COVID-19 in India-a statistical study. J Xidian Univ. 2020;14(4):1422–6.
Homer JB, Hirsch GB. System dynamics modeling for public health: background and opportunities. Am J Public Health. 2006;96(3):452–8. https://doi.org/10.2105/AJPH.2005.062059.
Heidenberger K, Flessa S. A system dynamics model for AIDS policy support in Tanzania. Eur J Oper Res. 1993;70(2):167–76. https://doi.org/10.1016/0377-2217(93)90036-M.
Meyerowitz-Katz G, Merone L. A systematic review and meta-analysis of published research data on COVID-19 infection-fatality rates. Int J Infect Dis. 2020;101:138–48. https://doi.org/10.1016/j.ijid.2020.09.1464.
WHO. Q&A on coronaviruses (COVID-19). 2020 [cited 2020 6.5.2020]; Available from: https://www.who.int/news-room/q-a-detail/q-a-coronaviruses.
Aronson, J., J. Brassey, and K. Mahtan. “When will it be over?” An introduction to viral reproductive numbers, R0 and Re. 2020 [cited 2020 6.5.2020]; Available from: https://www.cebm.net/covid-19/when-will-it-be-over-an-introduction-to-viral-reproduction-numbers-r0-and-re/.
Lelieveld J, Helleis F, Borrmann S, Cheng Y, Drewnick F, Haug G, et al. Model calculations of aerosol transmission and infection risk of COVID-19 in indoor environments. Int J Environ Res Public Health. 2020;17(21):8114. https://doi.org/10.3390/ijerph17218114.
PHE. Investigation of novel SARS-CoV-2 variant. Variant of Concern 2020 12/01. Technical Briefing Nr. 2. London: Public Health England; 2021.
Editorial, D.Ä. Zahl der Coronafälle in Wuhan offenbar höher als gemeldet. afp/aerzteblatt.de 2020 [cited 2021 20.01.2021]; Available from: https://www.aerzteblatt.de/nachrichten/119791/Zahl-der-Coronafaelle-in-Wuhan-offenbar-hoeher-als-gemeldet.
Hao X, Cheng S, Wu D, Wu T, Lin X, Wang C. Reconstruction of the full transmission dynamics of COVID-19 in Wuhan. Nature. 2020;584(7821):420–4. https://doi.org/10.1038/s41586-020-2554-8.
Yoon M, Kim JH, Sung J, Lim AY, Hwang MJ, Kim EH, et al. Population response to air pollution and the risk of coronavirus disease in Chinese cities during the early pandemic period. Int J Environ Res Public Health. 2021;18(5):2248. https://doi.org/10.3390/ijerph18052248.
McClymont H, Hu W. Weather variability and COVID-19 transmission: a review of recent research. Int J Environ Res Public Health. 2021;18(2):396. https://doi.org/10.3390/ijerph18020396.
Qi DJ, et al. The impact of scientific research in the early stages of the COVID-19 epidemic on government decision-making. Goverance Stud. 2020;36(2):21–31.
Government of China. Official website of the National Bureau of Statistics of China. 2021 [cited 2021 10.02.2021]; Available from: http://data.stats.gov.cn.
OECD. OECD official website. 2021 [cited 2021 10.02.2021]; Available from: https://stats.oecd.org.
China, N.H.C.o. 2019 China Health Statistics Yearbook. 2020 [cited 2021 12.02.2021]; Available from: www.yearbookchina.com.
Baker MG, et al. New Zealand’s COVID-19 elimination strategy. Med J Aust. 2020;213(198):10.5694.
Brauner JM, et al. Inferring the effectiveness of government interventions against COVID-19. Science. 2020;371(6531). https://doi.org/10.1126/science.abd9338.
Brauner, J.M., et al., The effectiveness of eight nonpharmaceutical interventions against COVID-19 in 41 countries. MedRxiv, 2020.
Persson, J., J.F. Parie, and S. Feuerriegel, Monitoring the COVID-19 epidemic with nationwide telecommunication data. arXiv preprint arXiv:2101.02521, 2021.
Priesemann, Viola, et al. Calling for pan-European commitment for rapid and sustained reduction in SARS-CoV-2 infections. The lancet. 2021;397(10269):92–3.
Bardenhagen K. Pandemie voll unter Kontrolle. Was Taiwan bei Corona besser gemacht hat. NTV-Politik. 2020;12. November 2020. https://www.n-tv.de/politik/Was-Taiwan-bei-Corona-besser-gemacht-hat-article22163913.html.
Blakely, Tony, et al. Maximizing the probability that the 6-week lock-down in Victoria delivers a COVID-19 free Australia. Med J Aust. 2020, preprint.
Philippe C, Marques N. The Zero Covid strategy protects people and economies more effectively. Paris, Bruxelles: Institut Économique Molinari; 2021.
Schneider, M.F., S. Duckett, and Y. Bar-Yam. Strategie gegen das Virus. 2021 [cited 2021 14.01.2021]; Available from: https://www.t-online.de/nachrichten/deutschland/id_89261072/corona-strategie-mit-zero-covid-feiern-wir-den-sommer-des-jahrhunderts-.html.
Yang J, et al. Who should be prioritized for COVID-19 vaccination in China? A descriptive study. BMC Med. 2021;19(1):1–13.
Moore S, Hill EM, Tildesley MJ, Dyson L, Keeling MJ. Vaccination and non-pharmaceutical interventions for COVID-19: a mathematical modelling study^. Lancet Infect Dis. 2021. https://doi.org/10.1016/S1473-3099(21)00143-2.
Wang K, Wong ELY, Ho KF, Cheung AWL, Yau PSY, Dong D, et al. Change of willingness to accept COVID-19 vaccine and reasons of vaccine hesitancy of working people at different waves of local epidemic in Hong Kong, China: repeated cross-sectional surveys. Vaccines. 2021;9(1):62. https://doi.org/10.3390/vaccines9010062.
Leng A, et al. Individual preferences for COVID-19 vaccination in China. Vaccine. 2021;39(2):247–54.
Kretschmer, F. Im “Kriegsmodus”: Auch China kämpft gegen eine zweite Corona-Welle. 2021 [cited 2021 20.01.2021]; Available from: https://www.rnd.de/gesundheit/corona-in-china-zweite-welle-in-mehreren-regionen-des-landes-ZJGL5NXCVRH27CDX726P67LZY4.html.
Ekong I, Chukwu E, Chukwu M. COVID-19 mobile positioning data contact tracing and patient privacy regulations: exploratory search of global response strategies and the use of digital tools in Nigeria. JMIR mHealth and uHealth. 2020;8(4):e19139. https://doi.org/10.2196/19139.
Wirtz BW, Müller WM, Weyerer JC. Digital pandemic response systems: a strategic management framework against Covid-19. Int J Public Adm. 2020:1–11. https://doi.org/10.1080/01900692.2020.1858316.
