Outcomes after R-CHOP in patients with newly diagnosed advanced follicular lymphoma: a 10-year follow-up analysis of the JCOG0203 trial

The Lancet Haematology - Tập 5 - Trang e520-e531 - 2018
Takashi Watanabe1,2, Kensei Tobinai1, Masashi Wakabayashi3, Yasuo Morishima4, Hirofumi Kobayashi5, Tomohiro Kinoshita6, Takayo Suzuki7, Motoko Yamaguchi8, Kiyoshi Ando9, Michinori Ogura10, Masafumi Taniwaki11, Naokuni Uike12, Tadashi Yoshino13, Sigeru Nawano14, Takashi Terauchi15,16, Tomomitsu Hotta17, Hirokazu Nagai18, Kunihiro Tsukasaki19
1Department of Haematology, National Cancer Center Hospital, Tokyo, Japan
2Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Mie, Japan
3JCOG Data Center/Operations Office, National Cancer Center Hospital, Tokyo, Japan
4Department of Haematology and Cell Therapy, Aichi Cancer Center Hospital, Nagoya, Japan
5Department of Haematology, Saitama Cancer Center, Saitama, Japan
6Department of Haematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
7Department of Haematology and Oncology, Shiga General Hospital, Shiga, Japan
8Department of Haematology and Oncology, Mie University Graduate School of Medicine, Mie, Japan
9Division of Haematology/Oncology, Department of Internal Medicine, Tokai University School of Medicine, Kanagawa, Japan
10Department of Haematology and Oncology, Nagoya Daini Red Cross Hospital, Nagoya, Japan
11Department of Molecular Haematology and Oncology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan
12Department of Haematology, National Hospital Organization Kyusyu Cancer Center, Fukuoka, Japan
13Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan
14Center for Radiological Science, International University of Health and Welfare, Mita Hospital, Tokyo, Japan
15Screening Technology and Development Division, Research Center for Cancer Prevention and Screening, National Cancer Center Hospital, Tokyo, Japan
16Department of Nuclear Medicine, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan
17National Hospital Organization Nagoya Medical Center, Nagoya, Japan
18Department of Haematology and Oncology Research, Nagoya Medical Center, Nagoya, Japan
19Department of Haematology, National Cancer Center Hospital East, Chiba, Japan

Tài liệu tham khảo

Swerdlow, 2016, The 2016 revision of the World Health Organization classification of lymphoid neoplasms, Blood, 127, 2375, 10.1182/blood-2016-01-643569 Campo, 2011, The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications, Blood, 117, 5019, 10.1182/blood-2011-01-293050 Dana, 1993, Long-term follow-up of patients with low-grade malignant lymphoma treated with doxorubicin-based chemotherapy or chemoimmunotherapy, J Clin Oncol, 11, 644, 10.1200/JCO.1993.11.4.644 Hiddemann, 2005, Blood, 106, 3725, 10.1182/blood-2005-01-0016 Marcus, 2005, CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma, Blood, 105, 1417, 10.1182/blood-2004-08-3175 Federico, 2013, R-CVP versus R-CHOP versus R-FM for initial treatment of patients with advanced-stage follicular lymphoma: results of the FOLL05 trial conducted by the Fondazione Italiana Linfomi, J Clin Oncol, 31, 1506, 10.1200/JCO.2012.45.0866 Luminari, 2017, Long-term results of the FOLL05 trial comparing R-CVP versus R-CHOP versus R-FM for the initial treatment of patients with advanced-stage symptomatic follicular lymphoma, J Clin Oncol, 36, 689, 10.1200/JCO.2017.74.1652 Czuczman, 1999, Treatment of patients with low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy, J Clin Oncol, 17, 268, 10.1200/JCO.1999.17.1.268 Watanabe, 2011, Phase II/III study of R-CHOP-21 versus R-CHOP-14 for untreated indolent b-cell non-Hodgkin's lymphoma: JCOG0203 trial, J Clin Oncol, 29, 3990, 10.1200/JCO.2011.34.8508 Ozer, 2000, 2000 update of recommendations for the use of hematopoietic colony-stimulating factors: evidence-based, clinical practice guidelines. American Society of Clinical Oncology Growth Factors Expert Panel, J Clin Oncol, 18, 3558, 10.1200/JCO.2000.18.20.3558 Hall, 1980, Confidence bands for a survival curve from censored data, Biometrika, 67, 133, 10.1093/biomet/67.1.133 Al-Tourah, 2008, Population-based analysis of incidence and outcome of transformed non-Hodgkin's lymphoma, J Clin Oncol, 26, 5165, 10.1200/JCO.2008.16.0283 Casulo, 2015, Transformed follicular non-Hodgkin lymphoma, Blood, 125, 40, 10.1182/blood-2014-04-516815 Montoto, 2007, Risk of clinical implications of transformation of follicular lymphoma to diffuse large B-cell lymphoma, J Clin Oncol, 25, 2426, 10.1200/JCO.2006.09.3260 Conconi, 2012, Incidence, risk factors and outcome of histologic transformation in follicular lymphoma, Br J Haematol, 157, 188, 10.1111/j.1365-2141.2012.09054.x Link, 2013, Rates and outcomes of follicular lymphoma transformation in the immunechemotherapy era: a report from the university of Iowa/Mayo clinic specialized program of research excellence molecular epidemiology resources, J Clin Oncol, 31, 3272, 10.1200/JCO.2012.48.3990 Sarcozy, 2016, Risk factors and outcomes for patients with follicular lymphoma who had histologic transformation after response to first-line immunochemotherapy in the PRIMA trial, J Clin Oncol, 34, 2575, 10.1200/JCO.2015.65.7163 Bachy, 2013, Long-term follow up of the FL2000 study comparing CHVP-interferon to CHVP-interferon plus rituximab in follicular lymphoma, Haematologica, 98, 1107, 10.3324/haematol.2012.082412 Herold, 2015, Long-term follow-up of rituximab plus first-line mitoxantrone, chlorambucil, prednisolone and interferon-alpha as maintenance therapy in follicular lymphoma, J Cancer Res Clin Oncol, 141, 1689, 10.1007/s00432-015-1963-9 Salles, 2013, Updated 6 year follow-up of the PRIMA study confirms the benefit of 2-year rituximab maintenance in follicular lymphoma patients responding to frontline immunechemotherapy, Blood, 122, 509, 10.1182/blood.V122.21.509.509 Flinn, 2014, Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study, Blood, 123, 2944, 10.1182/blood-2013-11-531327 Rummel, 2013, Bendamsutine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas: an open-label, multicenter, randomized, phase 3 non-inferiority trial, Lancet, 381, 1203, 10.1016/S0140-6736(12)61763-2 Salles, 2011, Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial, Lancet, 377, 42, 10.1016/S0140-6736(10)62175-7 Hiddemann, 2018, Immunotherapy with obinutuzumab or rituximab for previously untreated follicular lymphoma in the GALLIUM study: incidence of chemotherapy on efficacy and safety, J Clin Oncol, 36, 2395, 10.1200/JCO.2017.76.8960 Salles, 2017, Long term follow-up pf the PRIMA study: half of patients receiving rituximab maintenance remain progression free at 10 years, Blood, 130, 486 Magnano, 2017, Long-term safety and outcome of fludarabine, cyclophosphamide and mitoxantrone (FCM) regimen in previously untreated patients with advanced follicular lymphoma: 12 years follow-up of a phase 2 trial, Ann Hematol, 96, 639, 10.1007/s00277-017-2920-2 Sacci, 2008, Secondary malignancies after treatment for indolent non-Hodgkin's lymphoma: a 16-year follow-up study, Haematologica, 93, 398, 10.3324/haematol.12120 Carney, 2010, Therapy-related myelodysplastic syndrome and acute myeloid leukemia following fludarabine combination chemotherapy, Leukemia, 24, 2056, 10.1038/leu.2010.218 Bennett, 2005, Assessment of treatment-related myelodysplastic syndromes and acute myeloid leukemia in patients with non-Hodgkin lymphoma treated with tositumomab and iodine I131 tositumomab, Blood, 105, 4576, 10.1182/blood-2004-12-4690 Rummel, 2017, Bendamustine plus rituximab (B-R) versus CHOP plus rituximab (CHOP-R) as first-line treatment in patients with indolent lymphomas: nine-year updated results from the StiL NHL1 study, J Clin Oncol, 35, 7501, 10.1200/JCO.2017.35.15_suppl.7501 Cheson, 1999, Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas, J Clin Oncol, 17, 1244, 10.1200/JCO.1999.17.4.1244 Casulo, 2015, Early relapse of follicular lymphoma after rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone defines patients at high risk for death: an analysis from the National LymphoCare Study, J Clin Oncol, 33, 2516, 10.1200/JCO.2014.59.7534