Osteosarcoma of the spine: surgical treatment and outcomes

World Journal of Surgical Oncology - Tập 11 Số 1 - 2013
Feng Ding1, Xianghong Yang1, Tielong Liu1, Jianru Xiao1, Zhipeng Wu1, Quan Huang1, Jinghong Ma1, Wending Huang1, Wei Zheng1, Zhenggang Cui2, Huazi Xu3, Yue Teng4
1Spine Center, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai, 200003, China
2Department of Orthopedic Surgery, Nantong First People's Hospital, Nantong, 226001, China
3Department of Orthopedic Surgery, Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325027, China
4Department of Orthopedic Surgery, Wulumuqi General Hospital of Lanzhou Military Command, People's Liberation Army, Wulumuqi, 830000, China

Tóm tắt

AbstractBackgroundThe goal of this study was to determine whether there are correlations between various options of surgical treatment and long-term outcome for spinal osteosarcoma.MethodsThis was a retrospective review of 16 patients with spinal osteosarcoma, who underwent surgical treatment from 1999 to 2010. Seven patients were given totalen blocspondylectomy (TES), while nine received piecemeal resection (there were seven cases of total piecemeal spondylectomy, one of sagittal resection, and one of vertebrectomy). The outcome and prognosis of the patients were evaluated, grouped by surgical treatment.ResultsAll 16 cases were followed for an average of 42.4 months. At follow-up, all patients noted that pain had eased or had gradually disappeared. Three months after surgery, eight patients (50.0%) had improved 1 to 2 grades in their neurological status, based on Frankel scoring. Six (37.5%) patients experienced local recurrence of the tumor, nine (56.3%) had metastases, and five (31.3%) died of the disease. Of the six patients who received a wide or marginalen blocresection, none developed local recurrence or died from the disease. Conversely, of the ten patients who received intralesional or contaminated resections, six (60%) relapsed and five (50%) died from the disease.ConclusionsTES, with a wide margin, should be planned for patients with osteosarcoma of the cervical and thoracolumbar spine, whenever possible. When the patients are not candidates foren blocresection, total piecemeal spondylectomy is an appropriate choice for osteosarcoma in the mobile spine.

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World Journal of Surgical Oncology

Tập 11 Số 1

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