Osteonecrosis of the maxilla as a complication to chemotherapy: a case report

Special Care in Dentistry - Tập 22 Số 4 - Trang 142-146 - 2002
Eric Sung1, Stephen M. Chan2, Kari Sakurai3, Evelyn M Chung4
1Clinical Associate Professor, Department of Hospital Dentistry, Center for the Health Sciences, Rm. B3‐069, UCLA School of Dentistry, 10833 Le Conte Ave., Los Angeles, CA 90095‐1668
2Chief Resident, General Practice Residency, Department of Hospital Dentistry, Center for the Health Sciences, Rm. B3‐069, UCLA School of Dentistry, 10833 Le Conte Ave., Los Angeles, CA 90095‐1668
3Lecturer, Department of Hospital Dentistry, Center for the Health Sciences, Rm. B3-069, UCLA School of Dentistry, 10833 Le Conte Ave., Los Angeles, CA 90095-1668
4Adjunct Assistant Professor, Department of Hospital Dentistry, Center for the Health Sciences, Rm. B3-069, UCLA School of Dentistry, 10833 Le Conte Ave., Los Angeles, CA 90095-1668

Tóm tắt

AbstractNumerous oral complications have been documented as a consequence of chemotherapy for the treatment of cancer. One not so well documented consequence of this treatment is avascular necrosis or osteonecrosis of the underlying bone. In this case report, osteonecrosis of the maxilla in a 48‐year‐old female patient who was treated for acute myelogenous leukemia is presented. The patient had successfully completed both induction and consolidation chemotherapy without steroid administration. Possible causes and difficulties in diagnosis were reviewed.

Từ khóa


Tài liệu tham khảo

National Cancer Institute.Estimated new cancer cases and deaths for 2000.SEER Cancer Statistics Review 19731997. (http:www‐seer.ims.nci.nih.gov) Accessed on June 21 2000.

10.14219/jada.archive.1978.0304

Sung EC., 1995, Dental management of patients undergoing chemotherapy, J Calif Dent Assoc, 23, 55

10.1007/s005200050217

10.1016/0964-1955(96)00037-1

U.S. Department of Health and Human Services National Institutes of Health.Chemotherapy and your mouth publication #99–4361.

Sonis ST, 1990, Oral complications of cancer therapies. Pretreatment oral assessment, NCI Monographs, 9, 29

Sonis ST, 1992, Prevention and management of oral mucositis induced by antineoplastic therapy, Oncology, 5, 11

10.1002/1097-0142(19851101)56:9<2292::AID-CNCR2820560925>3.0.CO;2-8

10.1007/BF00350214

10.1002/1097-0142(19810901)48:5<1245::AID-CNCR2820480532>3.0.CO;2-E

10.1016/S0749-8063(05)80355-X

Usher BW, 1995, Steroid‐induced osteonecrosis of the humeral head, Orthopedics, 18, 47, 10.3928/0147-7447-19950101-10

10.1111/j.1365-2257.1994.tb00381.x

10.1111/j.1600-0609.1998.tb01085.x

10.1080/028418698429739

10.1016/S0009-9260(97)80253-X

10.1002/hed.2890040313

Jones DN., 1994, Multifocal osteonecrosis following chemotherapy and short‐term corticosteroid therapy in a patient with small‐cell bronchogenic carcinoma, J Nucl Med, 35, 1347

10.3109/02770909909065152

10.1136/bmj.288.6413.267

Marymount JV, 1986, Osteonecrosis of bone associated with combination chemotherapy without corticosteroids, Clin Orthop, 204, 150

Oral complications of cancer therapies: diagnosis prevention and treatment. NIH Consensus Statement Online 1989 Apr 17–19 (cited 2001 May 17);7(7)1–11.

10.1007/s003300050131