Osteoblast-specific Knockout of the Insulin-like Growth Factor (IGF) Receptor Gene Reveals an Essential Role of IGF Signaling in Bone Matrix Mineralization

Journal of Biological Chemistry - Tập 277 Số 46 - Trang 44005-44012 - 2002
Mei Zhang1, Shouhong Xuan2, Mary Bouxsein3, D. von Stechow3, Nagako Akeno1, M.-C. Faugere4, Hartmut H. Malluche4, Guisheng Zhao1, Clifford J. Rosen5, Argiris Efstratiadis2, Thomas L. Clemens1
1Department of Medicine, University of Cincinnati, Cincinnati, Ohio 45267, the
2Department of Genetics and Development, Columbia University, New York, New York 10032, the
3Orthopedic Biomechanics Laboratory, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, the
4Department of Medicine, University of Kentucky, Lexington, Kentucky 40536, and the
5Maine Center for Osteoporosis Research and Education, St. Joseph's Hospital, Bangor, Maine 04401

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Journal of Biological Chemistry

Tập 277 Số 46

44005-44012

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