Orexin-a elevation in antipsychotic-treated compared to drug-free patients with schizophrenia: A medication effect independent of metabolic syndrome

Journal of the Formosan Medical Association - Tập 121 - Trang 2172-2181 - 2022
Po-Yu Chen1,2, Chin-Kuo Chang3,4,5, Chun-Hsin Chen6,7,8, Su-Chen Fang9, Valeria Mondelli5, Chih-Chiang Chiu2,6, Mong-Liang Lu6,7, Ling-Ling Hwang1,10, Ming-Chyi Huang2,6,8
1Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
2Department of Psychiatry, Taipei City Psychiatric Center, Taipei City Hospital, Taipei, Taiwan
3Global Health Program, College of Public Health, National Taiwan University, Taipei, Taiwan
4Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
5Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK
6Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taiwan
7Department of Psychiatry, Wan Fang Hospital, Taipei, Taiwan
8Psychiatric Research Center, Wang-Fang Hospital, Taipei Medical University, Taipei, Taiwan
9Department of Nursing, Mackay Medical College, New Taipei City, Taiwan
10Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

Tài liệu tham khảo

McEvoy, 2005, Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III, Schizophr Res, 80, 19, 10.1016/j.schres.2005.07.014 Huang, 2009, Prevalence of metabolic syndrome among patients with schizophrenia or schizoaffective disorder in Taiwan, Acta Psychiatr Scand, 120, 274, 10.1111/j.1600-0447.2009.01401.x Gardner-Sood, 2015, Cardiovascular risk factors and metabolic syndrome in people with established psychotic illnesses: baseline data from the IMPaCT randomized controlled trial, Psychol Med, 45, 2619, 10.1017/S0033291715000562 Deh, 2009, Metabolic syndrome in people with schizophrenia: a review, World Psychiatr, 8, 15, 10.1002/j.2051-5545.2009.tb00199.x Thakore, 2004, Metabolic disturbance in first-episode schizophrenia, Br J Psychiatr Suppl, 47, S76, 10.1192/bjp.184.47.s76 Vancampfort, 2015, Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta-analysis, World Psychiatr : official journal of the World Psychiatric Association, 14, 339, 10.1002/wps.20252 Baptista, 2008, Pharmacological management of atypical antipsychotic-induced weight gain, CNS Drugs, 22, 477, 10.2165/00023210-200822060-00003 Sakurai, 1998, Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior, Cell, 92, 573, 10.1016/S0092-8674(00)80949-6 Kastin, 1999, Orexin A but not orexin B rapidly enters brain from blood by simple diffusion, J Pharmacol Exp Therapeut, 289, 219 Messina, 2018, Functional changes induced by orexin A and adiponectin on the sympathetic/parasympathetic balance, Front Physiol, 9, 259, 10.3389/fphys.2018.00259 Shirasaka, 1999, Sympathetic and cardiovascular actions of orexins in conscious rats, Am J Physiol, 277, R1780 Messina, 2014, Orexin-A controls sympathetic activity and eating behavior, Front Psychol, 5, 997, 10.3389/fpsyg.2014.00997 Park, 2015, Orexin A regulates plasma insulin and leptin levels in a time-dependent manner following a glucose load in mice, Diabetologia, 58, 1542, 10.1007/s00125-015-3573-0 Tsuneki, 2015, Hypothalamic orexin prevents hepatic insulin resistance via daily bidirectional regulation of autonomic nervous system in mice, Diabetes, 64, 459, 10.2337/db14-0695 Strawn, 2010, Low cerebrospinal fluid and plasma orexin-A (hypocretin-1) concentrations in combat-related posttraumatic stress disorder, Psychoneuroendocrinology, 35, 1001, 10.1016/j.psyneuen.2010.01.001 Steward, 2019, Reduced plasma orexin-A concentrations are associated with cognitive deficits in anorexia nervosa, Sci Rep, 9, 7910, 10.1038/s41598-019-44450-6 Lee, 2021, Differences in serum orexin-A levels between the acute and subacute withdrawal phases in individuals who use methamphetamine, Exp Clin Psychopharmacol, 29, 573, 10.1037/pha0000395 Tsuchimine, 2019, Reduced plasma orexin-A levels in patients with bipolar disorder, Neuropsychiatric Dis Treat, 15, 2221, 10.2147/NDT.S209023 Yamanaka, 2006, Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner, J Neurophysiol, 96, 284, 10.1152/jn.01361.2005 Linehan, 2019, Dopamine modulates excitatory transmission to orexin neurons in a receptor subtype-specific manner, Am J Physiol Regul Integr Comp Physiol, 316, R68, 10.1152/ajpregu.00150.2018 Chien, 2015, Elevated plasma orexin A levels in a subgroup of patients with schizophrenia associated with fewer negative and disorganized symptoms, Psychoneuroendocrinology, 53, 1, 10.1016/j.psyneuen.2014.12.012 Chen, 2019, Orexin-A levels in relation to the risk of metabolic syndrome in patients with schizophrenia taking antipsychotics, Int J Neuropsychopharmacol, 22, 28, 10.1093/ijnp/pyy075 Fadel, 2002, Differential activation of orexin neurons by antipsychotic drugs associated with weight gain, J Neurosci, 22, 6742, 10.1523/JNEUROSCI.22-15-06742.2002 Monda, 2008, Olanzapine blocks the sympathetic and hyperthermic reactions due to cerebral injection of orexin A, Peptides, 29, 120, 10.1016/j.peptides.2007.10.016 Monda, 2003, Haloperidol reduces the sympathetic and thermogenic activation induced by orexin A, Neurosci Res, 45, 17, 10.1016/S0168-0102(02)00191-8 Monda, 2004, Clozapine blocks sympathetic and thermogenic reactions induced by orexin A in rat, Physiol Res, 53, 507, 10.33549/physiolres.930516 Monda, 2018, Functional changes of orexinergic reaction to psychoactive substances, Mol Neurobiol, 10.1007/s12035-017-0865-z Williams, 2020, Aberrant glycosylation in schizophrenia: a review of 25 years of post-mortem brain studies, Mol Psychiatr, 10.1038/s41380-020-0761-1 Lee, 1990, Reliability and validity of using a Brief psychiatric symptom rating Scale in clinical practice, J Formos Med Assoc, 89, 1081 Grundy, 2005, Diagnosis and management of the metabolic syndrome: an American heart association/national heart, lung, and blood Institute scientific statement, Circulation, 112, 2735, 10.1161/CIRCULATIONAHA.105.169404 Pearson, 1909, Determination of the coefficient of correlation, Science, 30, 23, 10.1126/science.30.757.23 Dalal, 2003, Lower CSF orexin A (hypocretin-1) levels in patients with schizophrenia treated with haloperidol compared to unmedicated subjects, Mol Psychiatr, 8, 836, 10.1038/sj.mp.4001363 Basoglu, 2010, Plasma orexin A, ghrelin, cholecystokinin, visfatin, leptin and agouti-related protein levels during 6-week olanzapine treatment in first-episode male patients with psychosis, Int Clin Psychopharmacol, 25, 165, 10.1097/YIC.0b013e3283377850 Messina, 2017, Role of autonomic nervous system and orexinergic system on adipose tissue, Front Physiol, 8, 137, 10.3389/fphys.2017.00137 Ahlenius, 1999, Clozapine: dopamine D1 receptor agonism in the prefrontal cortex as the code to decipher a Rosetta stone of antipsychotic drugs, Pharmacol Toxicol, 84, 193, 10.1111/j.1600-0773.1999.tb01482.x Tuplin, 2017, Aripiprazole, A drug that displays partial agonism and functional selectivity, Curr Neuropharmacol, 15, 1192, 10.2174/1570159X15666170413115754 Sakurai, 2003, Orexin: a link between energy homeostasis and adaptive behaviour, Curr Opin Clin Nutr Metab Care, 6, 353, 10.1097/00075197-200307000-00001 Chieffi, 2017, Orexin system: the key for a healthy life, Front Physiol, 8, 10.3389/fphys.2017.00357