Oral mucosal fibroblasts overexpressing BMP-2 differentiate into osteoblasts and participate in new bone formation during bone regeneration

Hirata, 2003, Transplantation of skin fibroblasts expressing BMP-2 promotes bone repair more effectively than those expressing Runx2, Bone, 32, 502, 10.1016/S8756-3282(03)00054-1 Umehara, 2012, Canine oral mucosal fibroblasts differentiate into osteoblastic cells in response to BMP-2, Anat Rec (Hoboken), 295, 1327, 10.1002/ar.22510 Sersa, 2008, Electrochemotherapy in treatment of tumours, Eur J Surg Oncol: J Eur Soc Surg Oncol Br Assoc Surg Oncol, 34, 232, 10.1016/j.ejso.2007.05.016 Landstrom, 2010, Electroporation therapy of skin cancer in the head and neck area, Dermatol Surg: Off Publ Am Soc Dermatol Surg, 36, 1245, 10.1111/j.1524-4725.2010.01617.x Low, 2009, DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer, Hum Gene Ther, 20, 1269, 10.1089/hum.2009.067 Stoll, 2001, Epstein-Barr virus/human vector provides high-level, long-term expression of alpha1-antitrypsin in mice, Mol Ther, 4, 122, 10.1006/mthe.2001.0429 Mucke, 1997, Suitability of Epstein-Barr virus-based episomal vectors for expression of cytokine genes in human lymphoma cells, Gene Ther, 4, 82, 10.1038/sj.gt.3300363 Lufino, 2008, Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression, Mol Ther, 16, 1525, 10.1038/mt.2008.156 Min, 2005, Improved gene expression pattern using Epstein-Barr virus (EBV)-based plasmid and cationic emulsion, Biomaterials, 26, 1063, 10.1016/j.biomaterials.2004.04.005 Lindner, 2007, The plasmid replicon of Epstein-Barr virus: mechanistic insights into efficient, licensed, extrachromosomal replication in human cells, Plasmid, 58, 1, 10.1016/j.plasmid.2007.01.003 Min, 2003, Prolonged gene expression in primary porcine pancreatic cells using an Epstein-Barr virus-based episomal vector, Biochem Biophys Res Commun, 305, 108, 10.1016/S0006-291X(03)00689-2 Weir, 2008, Mesenchymal stem cells: isolation, characterisation and in vivo fluorescent dye tracking, Heart, Lung Circ, 17, 395, 10.1016/j.hlc.2008.01.006 Chalfie, 1995, Green fluorescent protein, Photochem Photobiol, 62, 651, 10.1111/j.1751-1097.1995.tb08712.x Mehrara, 1999, Adenovirus-mediated gene therapy of osteoblasts in vitro and in vivo, J Bone Miner Res: Off J Am Soc Bone Miner Res, 14, 1290, 10.1359/jbmr.1999.14.8.1290 Shah, 2005, Molecular optical imaging: applications leading to the development of present day therapeutics, NeuroRx: J Am Soc Exp NeuroTher, 2, 215, 10.1602/neurorx.2.2.215 Goldmacher, 2013, Tracking transplanted bone marrow stem cells and their effects in the rat MCAO stroke model, PloS One, 8, e60049, 10.1371/journal.pone.0060049 Kadowaki, 2004, Isolation and characterization of a mesenchymal cell line that differentiates into osteoblasts in response to BMP-2 from calvariae of GFP transgenic mice, Bone, 34, 993, 10.1016/j.bone.2004.01.018