Oral immunization with Salmonella harboring a Sm14-based DNA vaccine does not protect mice against Schistosoma mansoni infection

Chitsulo, 2004, Schistosomiasis, Nat Rev Microbiol, 2, 12, 10.1038/nrmicro801 Wilson, 2006, Schistosome vaccines: a critical appraisal, Mem Inst Oswaldo Cruz, 101, 13, 10.1590/S0074-02762006000900004 Capron, 2002, Prospects for a schistosome vaccine, Curr Drug Targets Immune Endocr Metab Disord, 2, 281, 10.2174/1568008023340587 Pearce, 2003, Progress towards a vaccine for schistosomiasis, Acta Trop, 86, 309, 10.1016/S0001-706X(03)00062-7 Bergquist, 2002, Blueprint for schistosomiasis vaccine development, Acta Trop, 82, 183, 10.1016/S0001-706X(02)00048-7 Kofta, 2001, c-DNA vaccination against parasitic infections: advantages and disadvantages, Vet Parasitol, 100, 3, 10.1016/S0304-4017(01)00478-2 Dupré, 1999, Control of schistosomiasis pathology by combination of Sm28GST DNA immunization and praziquantel treatment, J Infect Dis, 180, 454, 10.1086/314875 Da'Dara, 2003, A DNA-prime/protein-boost vaccination regimen enhances Th2 immune responses but not protection following Schistosoma mansoni infection, Parasite Immunol, 25, 429, 10.1111/j.1365-3024.2003.00651.x Chlichlia, 2001, DNA vaccination with asparaginyl endopeptidase (Sm32) from the parasite Schistosoma mansoni: anti-fecundity effect induced in mice, Vaccine, 20, 439, 10.1016/S0264-410X(01)00345-0 Shalaby, 2003, Protection against Schistosoma mansoni utilizing DNA vaccination with genes encoding Cu/Zn cytosolic superoxide dismutase, signal peptide-containing superoxide dismutase and glutathione peroxidase enzymes, Vaccine, 22, 130, 10.1016/S0264-410X(03)00535-8 Cook, 2004, Nucleic acid vaccination with Schistosoma mansoni antioxidant enzyme cytosolic superoxide dismutase and the structural protein filamin confers protection against the adult worm stage, Infect Immun, 72, 6112, 10.1128/IAI.72.10.6112-6124.2004 Fonseca, 2006, Co-administration of plasmid expressing IL-12 with 14-kDa Schistosoma mansoni fatty acid-binding protein cDNA alters immune response profiles and fails to enhance protection induced by Sm14 DNA vaccine alone, Microbes Infect, 8, 2509, 10.1016/j.micinf.2006.06.008 Nascimento, 2002, Protective immunity of single and multi-antigen DNA vaccines against schistosomiasis, Mem Inst Oswaldo Cruz, 97, 105, 10.1590/S0074-02762002000900021 Dietrich, 1999, Delivery of DNA vaccines by attenuated intracellular bacteria, Immunol Today, 20, 251, 10.1016/S0167-5699(98)01431-5 Weiss, 2001, Bacteria-mediated transfer of eukaryotic expression plasmids into mammalian host cells, Biol Chem, 382, 533, 10.1515/BC.2001.067 Pacheco, 2005, Oral administration of a live Aro attenuated Salmonella vaccine strain expressing 14-kDa Schistosoma mansoni fatty acid-binding protein induced partial protection against experimental schistosomiasis, Acta Trop, 95, 132, 10.1016/j.actatropica.2005.05.007 Sambrook, 2001 Pellegrino, 1956, Técnica de perfusão para colheita de Schistosoma mansoni em cobaias experimentalmente infectadas, Ver Bras Malariol D Trop, 8, 589 Donnelly, 2003, Technical and regulatory hurdles for DNA vaccines, Int J Parasitol, 33, 457, 10.1016/S0020-7519(03)00056-0 Andrade, 1964, Mild prolonged schistosomiasis: alterations in host response with time and the development of portal fibrosis, Trans R Soc Trop Méd Hyg, 58, 447 Sandor, 2003, Granulomas in schistosome and mycobacterial infections: a model of local immune responses, Trends Immunol, 24, 44, 10.1016/S1471-4906(02)00006-6 Wilson, 2007, Immunopathology of schistosomiasis, Immunol Cell Biol, 85, 148, 10.1038/sj.icb.7100014 Pellegrino, 1965, The oogram method for the screening of drugs in schistosomiasis mansoni, Am J Trop Med Hyg, 14, 363, 10.4269/ajtmh.1965.14.363 Pearce, 1991, Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni, J Exp Med, 173, 159, 10.1084/jem.173.1.159 Cheever, 1992, The role of cytokines in the pathogenesis of hepatic granulomatous disease in Schistosoma mansoni infected mice, Mem Inst Oswaldo Cruz, 87, 81, 10.1590/S0074-02761992000800011 Hoffmann, 2000, IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis, J Immunol, 164, 6406, 10.4049/jimmunol.164.12.6406