Oral corticosteroids and fracture risk: relationship to daily and cumulative doses

Rheumatology - Tập 39 Số 12 - Trang 1383-1389 - 2000
Tjeerd van Staa1, Hubert G. M. Leufkens1, Lucien Abenhaim2,3, B. Zhang1, Cyrus Cooper4
1Department of Pharmacoepidemiology and Pharmacotherapy, University of Utrecht, Sorbonnelaan 16, Utrecht, The Netherlands,
2McGill University, Department of Epidemiology & Biostatistics, Montreal, Canada and
3Sir Mortimer B. Davis Jewish General Hospital, Centre for Clinical Epidemiology and Community Studies, Montreal,
4MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK

Tóm tắt

Từ khóa


Tài liệu tham khảo

Lukert B. Glucocorticoid‐induced osteoporosis. In: Marcus R, Feldman D, Kelsey J, eds. Osteoporosis. San Diego: Academic Press, 1996;801–13.

Reid IR. Gluco‐corticoid‐induced osteoporosis and other forms of secondary osteoporosis. In: Meunier PJ, ed. Osteoporosis: diagnosis and management. London: Martin Dunitz, 1998:233–50.

Luengo M, Picado C, Del Rio L, Guañabens N, Montserrat JM, Setoain J. Vertebral fractures in steroid dependent asthma and involutional osteoporosis: a comparative study. Thorax1991;46:803–6.

Cooper C, Coupland C, Mitchell M. Rheumatoid arthritis, corticosteroid therapy and hip fracture. Ann Rheum Dis1995;54:49–52.

Lems WF, Jahangier ZN, Jacobs JWG, Bulsma JWJ. Vertebral fractures in patients with rheumatoid arthritis treated with corticosteroids. Clin Exp Rheumatol1995; 13:293–7.

McDougall R, Sibley J, Haga M, Russell A. Outcome in patients with rheumatoid arthritis receiving prednisone compared to matched controls. J Rheumatol1994;21: 1207–13.

Saag KG, Koehnke R, Caldwell JR, et al. Low dose long‐term corticosteroid therapy in rheumatoid arthritis: An analysis of serious adverse events. Am J Med1994; 96:115–23.

Michel BA, Bloch DA, Wolfe F, Fries JF. Fractures in rheumatoid arthritis: An evaluation of associated risk factors. J Rheumatol1993;20:1666–9.

Laan RFJM, van Riel PLCM, van Erning LJTO, Lemmens JAM, Ruijs SHJ, van de Putte LBA. Vertebral osteoporosis in rheumatoid arthritis patients: Effect of low dose prednisone therapy. Br J Rheumatol1992;31:91–6.

Butler RC, Davie MWJ, Worsfold M, Sharp CA. Bone mineral content in patients with rheumatoid arthritis: Relationship to low‐dose steroid therapy. Br J Rheumatol1991;30:86–90.

Michel BA, Bloch DA, Fries JF. Predictors of fractures in early rheumatoid arthritis. J Rheumatol1991;18:804–9.

Sambrook PN, Eisman JA, Yeates MG, Pocock NA, Eberl S, Champion GD. Osteoporosis in rheumatoid arthritis: safety in low dose corticosteroids. Ann Rheum Dis1986;45:950–3.

Verstraeten A, Dequeker J. Vertebral and peripheral bone mineral content and fracture incidence in postmenopausal patients with rheumatoid arthritis: effect of low dose corticosteroids. Ann Rheum Dis1986;45:852–7.

Dykman TR, Gluck OS, Murphy WA, Hahn TJ, Hahn BH. Evaluation of factors associated with glucocorticoid‐induced osteopenia in patients with rheumatic diseases. Arthritis Rheum1985;28:361–8.

Hooyman JR, Melton JL IIII, Nelson AM, O'Fallon MW, Riggs BL. Fractures after rheumatoid arthritis. A population-based study. Arthritis Rheum1984;27:1353–61.

Adinoff AD, Hollister MD, Roger J. Steroid‐induced fractures and bone loss in patients with asthma. New Engl J Med1983;309:265–8.

Saville PD, Oved K. Osteoporosis of rheumatoid arthritis: influence of age, sex and corticosteroids. Arthritis Rheum1967;10:423–31.

McConkey B, Fraser GM, Bligh AS. Osteoporosis and purpura in rheumatoid disease: Prevalence and relation to treatment with corticosteroids. Q J Med, New Series XXXI1962;124:419–27.

Van Staa TP, Leufkens B, Abenhaim L, Zhang B, Cooper C. Use of oral corticosteroids and risk of fractures. J Bone Miner Res2000;15:993–1000.

Hall G. Pharmacoepidemiology using a UK Database of Primary Care Records. Pharmacoepidemiol Drug Safety1992;1:33–7.

Lis Y, Mann RD. The Vamp Research Multi‐purpose Database in the U.K. J Clin Epidemiol1995;48:431–43.

Mann RD, Hall G, Chukwujindu J. Research implications of computerised primary care. Post Marketing Surveillance1992;5:259–68.

Hollowell J. General Practice Research Database (GPRD): Scope and quality of data. London: Office of Population Censuses and Statistics, 1994.

Anonymous. The general practice research database: information for researchers. London: Office for National Statistics, 1996.

Walley T, Mantgani A. The UK General Practice Research Database. Lancet1997;350:1097–9.

Jick H, Jick SS, Derby LE. Validation of Information recorded on general practitioner based computerised data resource in the United Kingdom. Br Med J1991;302: 766–8.

Jick H, Terris BZ, Derby LE, Jick SS. Further validation of information recorded on a general practitioner based computerised data resource in the United Kingdom. Pharmacoepidemiol Drug Safety1992;1:347–9.

Nazareth I, King M, Haines A, Rangel L, Myers S. Accuracy of diagnosis of psychosis on general practice computer system. Br Med J1993;307:32–4.

Van Staa TP, Abenhaim L. The quality of information recorded on a UK database of primary care records: a study of hospitalization due to hypoglycemia and other conditions. Pharmacoepidemiol Drug Safety1994;3:15–21.

British Medical Association and the Royal Pharmaceutical Society of Great Britain. British National Formulary Number 32 (September 1996). Wallingford, UK: Pharmaceutical Press, 1996.

Breslow NE, Day NE. Statistical methods in cancer research. Lyon: International Agency for Research on Cancer, 1987.

Greenland S. Dose–response and trend analysis in epidemiology: alternatives to categorical analysis. Epidemiology1995;6:356–65.

Durrleman S, Simon R. Flexible regression models with cubic splines. Stat Med1989;8:551–61.

Pizer M. Numerical Computing and Mathematical Analysis. Chicago: Science Research Associates, 1975. Chapter 4, pp. 251–456.

SAS/GRAPH Software: Reference, Version 6, First Edition, Vol. 1. Cary, NC: SAS Institute,1996.

Dequeker J, Westhovens R. Low dose corticosteroid associated osteoporosis in rheumatoid arthritis and its prophylaxis and treatment: Bones of contention. J Rheumatol1995;22:1013–9.

Spector TD, Sambrook PN. Steroid osteoporosis. Br Med J1993;307:519–20.

Cooper C. Osteoporosis in rheumatological practice: questions to be answered. Ann Rheum Dis1995;54:1–2.

Henderson NK, Sambrook PN. Relationship between osteoporosis and arthritis and effect of corticosteroids and other drugs on bone. Curr Opin Rheumatol1996; 8:365–9.

Eastell R, Reid DM, Compston J, et al. A UK consensus group on management of glucocorticoid induced osteoporosis: an update. J Intern Med1998;244:271–92.

van Staa TP, Abenheim L, Cooper C, Zhang B, Leufkens HGM. The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results. Pharmacoepidemiol Drug Safety 2001; in press.

Cooper C, O'Neill T, Silman A. The epidemiology of vertebral fractures. Bone1993;14:S89–97.