Oral administration of a mixture of probiotics protects against food allergy via induction of CD103+ dendritic cells and modulates the intestinal microbiota

Atarashi, 2013, Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota, Nature, 500, 232, 10.1038/nature12331 Atarashi, 2011, Induction of colonic regulatory T cells by indigenous Clostridium species, Science, 331, 337, 10.1126/science.1198469 Barletta, 2013, Probiotic VSL#3-induced TGF-beta ameliorates food allergy inflammation in a mouse model of peanut sensitization through the induction of regulatory T cells in the gut mucosa, Molecular Nutrition & Food Research, 57, 2233, 10.1002/mnfr.201300028 Bunker, 2015, Innate and adaptive humoral responses coat distinct commensal bacteria with immunoglobulin A, Immunity, 43, 541, 10.1016/j.immuni.2015.08.007 Bunyavanich, 2015, Systems biology of asthma and allergic diseases: A multiscale approach, The Journal of Allergy and Clinical Immunology, 135, 31, 10.1016/j.jaci.2014.10.015 Capobianco, 2008, Oral sensitization with shrimp tropomyosin induces in mice allergen-specific IgE, T cell response and systemic anaphylactic reactions, International Immunology, 20, 1077, 10.1093/intimm/dxn065 Cerovic, 2014, Intestinal macrophages and dendritic cells: What's the difference?, Trends in Immunology, 35, 270, 10.1016/j.it.2014.04.003 Chen, 2018, Sugary Kefir Strain Lactobacillus mali APS1 ameliorated hepatic steatosis by regulation of SIRT-1/Nrf-2 and gut microbiota in rats, Molecular Nutrition & Food Research, 62, e1700903, 10.1002/mnfr.201700903 Corthesy, 2013, Multi-faceted functions of secretory IgA at mucosal surfaces, Frontiers in Immunology, 4, 185, 10.3389/fimmu.2013.00185 Denning, 2011, Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization, Journal of Immunology, 187, 733, 10.4049/jimmunol.1002701 Gao, 2018, Impact of the gut microbiota on intestinal immunity mediated by tryptophan metabolism, Frontiers in Cellular and Infection Microbiology, 8, 13, 10.3389/fcimb.2018.00013 Hardy, 2013, Probiotics, prebiotics and immunomodulation of gut mucosal defences: Homeostasis and immunopathology, Nutrients, 5, 1869, 10.3390/nu5061869 Hesla, 2014, Impact of lifestyle on the gut microbiota of healthy infants and their mothers-the ALADDIN birth cohort, FEMS Microbiology Ecology, 90, 791, 10.1111/1574-6941.12434 Huang, 2017, The microbiome in allergic disease: Current understanding and future opportunities-2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology, The Journal of Allergy and Clinical Immunology, 139, 1099, 10.1016/j.jaci.2017.02.007 Jia, 2018, Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis, Nature Reviews Gastroenterology & Hepatology, 15, 111, 10.1038/nrgastro.2017.119 Kawamoto, 2014, Foxp3(+) T cells regulate immunoglobulin a selection and facilitate diversification of bacterial species responsible for immune homeostasis, Immunity, 41, 152, 10.1016/j.immuni.2014.05.016 Koplin, 2018, Prevention of food allergies, Immunology and Allergy Clinics of North America, 38, 1, 10.1016/j.iac.2017.09.001 Kourosh, 2018, Fecal microbiome signatures are different in food-allergic children compared to siblings and healthy children, Pediatric Allergy and Immunology, 29, 545, 10.1111/pai.12904 Kukkonen, 2010, High intestinal IgA associates with reduced risk of IgE-associated allergic diseases, Pediatric Allergy and Immunology, 21, 67, 10.1111/j.1399-3038.2009.00907.x Lawley, 2012, Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice, PLOS Pathogens, 8, e1002995, 10.1371/journal.ppat.1002995 Lim, 2017, Lactobacillus johnsonii CJLJ103 attenuates colitis and memory impairment in mice by inhibiting gut microbiota lipopolysaccharide production and NF-κB activation, Journal of Functional Foods, 34, 359, 10.1016/j.jff.2017.05.016 Di Luccia, 2018, Lactobacillus gasseri SF1183 protects the intestinal epithelium and prevents colitis symptoms in vivo, Journal of Functional Foods, 42, 195, 10.1016/j.jff.2017.12.049 Merad, 2013, The dendritic cell lineage: Ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting, Annual Review of Immunology, 31, 563, 10.1146/annurev-immunol-020711-074950 Mowat, 2003, Anatomical basis of tolerance and immunity to intestinal antigens, Nature Reviews Immunology, 3, 331, 10.1038/nri1057 Mowat, 2014, Regional specialization within the intestinal immune system, Nature Reviews Immunology, 14, 667, 10.1038/nri3738 Noval Rivas, 2013, A microbiota signature associated with experimental food allergy promotes allergic sensitization and anaphylaxis, The Journal of Allergy and Clinical Immunology, 131, 201, 10.1016/j.jaci.2012.10.026 Noval Rivas, 2016, Regulatory T cells in allergic diseases, The Journal of Allergy and Clinical Immunology, 138, 639, 10.1016/j.jaci.2016.06.003 Oh, 2018, Probiotic and anti-inflammatory potential of Lactobacillus rhamnosus 4B15 and Lactobacillus gasseri 4M13 isolated from infant feces, PLoS One, 13, e0192021, 10.1371/journal.pone.0192021 Pabst, 2012, Oral tolerance to food protein, Mucosal Immunology, 5, 232, 10.1038/mi.2012.4 Rescigno, 2014, Dendritic cell-epithelial cell crosstalk in the gut, Immunological Reviews, 260, 118, 10.1111/imr.12181 Robertson, 2005, Mucispirillum schaedleri gen. nov., sp. nov., a spiral-shaped bacterium colonizing the mucus layer of the gastrointestinal tract of laboratory rodents, International Journal of Systematic and Evolutionary Microbiology, 55, 1199, 10.1099/ijs.0.63472-0 Rodriguez, 2012, Infant gut microbiota is protective against cow's milk allergy in mice despite immature ileal T-cell response, FEMS Microbiology Ecology, 79, 192, 10.1111/j.1574-6941.2011.01207.x Rodriguez-Nogales, 2017, Differential intestinal anti-inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and microbiota composition, Molecular Nutrition & Food Research, 61, 10.1002/mnfr.201700144 Rothschild, 2018, Environment dominates over host genetics in shaping human gut microbiota, Nature, 555, 210, 10.1038/nature25973 Sampson, 2018, Mechanisms of food allergy, The Journal of Allergy and Clinical Immunology, 141, 11, 10.1016/j.jaci.2017.11.005 Sanchez, 2017, Probiotics, gut microbiota, and their influence on host health and disease, Molecular Nutrition & Food Research, 61, 10.1002/mnfr.201600240 Savage, 2015, Food allergy: Epidemiology and natural history, Immunology and Allergy Clinics of North America, 35, 45, 10.1016/j.iac.2014.09.004 Scott, 2011, Intestinal CD103+ dendritic cells: Master regulators of tolerance?, Trends in Immunology, 32, 412, 10.1016/j.it.2011.06.003 Shin, 2014, Preventive effects of skullcap (Scutellaria baicalensis) extract in a mouse model of food allergy, Journal of Ethnopharmacology, 153, 667, 10.1016/j.jep.2014.03.018 Sicherer, 2014, Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment, The Journal of Allergy and Clinical Immunology, 133, 291, 10.1016/j.jaci.2013.11.020 Smit, 2011, The role of intestinal dendritic cells subsets in the establishment of food allergy, Clinical & Experimental Allergy, 41, 890, 10.1111/j.1365-2222.2011.03738.x Spasova, 2014, Blowing on embers: Commensal microbiota and our immune system, Frontiers in Immunology, 5, 318, 10.3389/fimmu.2014.00318 Stefka, 2014, Commensal bacteria protect against food allergen sensitization, Proceedings of the National Academy of Sciences of the United States of America, 111, 13145, 10.1073/pnas.1412008111 Steinman, 2012, Decisions about dendritic cells: Past, present, and future, Annual Review of Immunology, 30, 1, 10.1146/annurev-immunol-100311-102839 Sun, 2007, Impact of CD40 ligand, B cells, and mast cells in peanut-induced anaphylactic responses, Journal of Immunology, 179, 6696, 10.4049/jimmunol.179.10.6696 Tamburini, 2016, The microbiome in early life: Implications for health outcomes, Nature Medicine, 22, 713, 10.1038/nm.4142 Tu, 2017, Interleukin-4 inhibits regulatory T cell differentiation through regulating CD103+ dendritic cells, Frontiers in Immunology, 8, 214, 10.3389/fimmu.2017.00214 Turner, 2018, Primary prevention of food allergy: Translating evidence from clinical trials to population-based recommendations, The Journal of Allergy and Clinical Immunology: In Practice, 6, 367, 10.1016/j.jaip.2017.12.015 Veenbergen, 2016, Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103(+) dendritic cells, Mucosal Immunology, 9, 894, 10.1038/mi.2015.118 Xiao, 2014, A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome, FEMS Microbiology Ecology, 87, 357, 10.1111/1574-6941.12228 Yamazaki, 2013, Dendritic cells in the periphery control antigen-specific natural and induced regulatory T cells, Frontiers in Immunology, 4, 151, 10.3389/fimmu.2013.00151