Oral Immunotherapy for Food Allergy

Gupta, 2011, The prevalence, severity, and distribution of childhood food allergy in the United States, Pediatrics, 128, e9, 10.1542/peds.2011-0204

Chafen, 2010, Diagnosing and managing common food allergies: a systematic review, JAMA, 303, 1848, 10.1001/jama.2010.582

Kim, 2013, The effects of elimination diet on nutritional status in subjects with atopic dermatitis, Nutr Res Pract, 7, 488, 10.4162/nrp.2013.7.6.488

Hobbs, 2015, Food allergies affect growth in children, J Allergy Clin Immunol Pract, 3, 133, 10.1016/j.jaip.2014.11.004

Nowak-Wegrzyn, 2011, Future therapies for food allergies, J Allergy Clin Immunol, 127, 558, 10.1016/j.jaci.2010.12.1098

Nurmatov, 2012, Allergen-specific oral immunotherapy for peanut allergy, Cochrane Database Syst Rev, 10.1002/14651858.CD009014.pub2

Sicherer, 2010, Food allergy, J Allergy Clin Immunol, 125, S116, 10.1016/j.jaci.2009.08.028

Bock, 2007, Further fatalities caused by anaphylactic reactions to food, 2001-2006, J Allergy Clin Immunol, 119, 1016, 10.1016/j.jaci.2006.12.622

Wensing, 2002, The range of minimum provoking doses in hazelnut-allergic patients as determined by double-blind, placebo-controlled food challenges, Clin Exp Allergy, 32, 1757, 10.1046/j.1365-2222.2002.01555.x

Sampson, 2006, Risk-taking and coping strategies of adolescents and young adults with food allergy, J Allergy Clin Immunol, 117, 1440, 10.1016/j.jaci.2006.03.009

Bock, 2001, Fatalities due to anaphylactic reactions to foods, J Allergy Clin Immunol, 107, 191, 10.1067/mai.2001.112031

Nguyen-Luu, 2012, Inadvertent exposures in children with peanut allergy, Pediatr Allergy Immunol, 23, 133, 10.1111/j.1399-3038.2011.01235.x

Lieberman, 2011, Quality of life in food allergy, Curr Opin Allergy Clin Immunol, 11, 236, 10.1097/ACI.0b013e3283464cf0

Hofmann, 2009, Safety of a peanut oral immunotherapy protocol in children with peanut allergy, J Allergy Clin Immunol, 124, 286, 10.1016/j.jaci.2009.03.045

Kulis, 2015, Diagnosis, management, and investigational therapies for food allergies, Gastroenterology, 148, 1132, 10.1053/j.gastro.2015.01.034

Burks, 2012, Oral immunotherapy for treatment of egg allergy in children, N Engl J Med, 367, 233, 10.1056/NEJMoa1200435

Vickery, 2014, Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy, J Allergy Clin Immunol, 133, 468, 10.1016/j.jaci.2013.11.007

Staden, 2007, Specific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction, Allergy, 62, 1261, 10.1111/j.1398-9995.2007.01501.x

Blumchen, 2010, Oral peanut immunotherapy in children with peanut anaphylaxis, J Allergy Clin Immunol, 126, 83, 10.1016/j.jaci.2010.04.030

Keet, 2013, Long-term follow-up of oral immunotherapy for cow's milk allergy, J Allergy Clin Immunol, 132, 737, 10.1016/j.jaci.2013.05.006

Gorelik, 2015, Suppression of the immunologic response to peanut during immunotherapy is often transient, J Allergy Clin Immunol, 135, 1283, 10.1016/j.jaci.2014.11.010

Caminiti, 2015, oral immunotherapy for egg allergy: a double-blind placebo-controlled study, with postdesensitization follow-up, J Allergy Clin Immunol Pract, 3, 532, 10.1016/j.jaip.2015.01.017

Oppenheimer, 1992, Treatment of peanut allergy with rush immunotherapy, J Allergy Clin Immunol, 90, 256, 10.1016/0091-6749(92)90080-L

Patriarca, 2006, Oral rush desensitization in peanut allergy: a case report, Dig Dis Sci, 51, 471, 10.1007/s10620-006-3157-4

Mansfield, 2006, Successful oral desensitization for systemic peanut allergy, Ann Allergy Asthma Immunol, 97, 266, 10.1016/S1081-1206(10)60026-9

Jones, 2009, Clinical efficacy and immune regulation with peanut oral immunotherapy, J Allergy Clin Immunol, 124, 292, 10.1016/j.jaci.2009.05.022

Varshney, 2011, A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response, J Allergy Clin Immunol, 127, 654, 10.1016/j.jaci.2010.12.1111

Anagnostou, 2011, Efficacy and safety of high-dose peanut oral immunotherapy with factors predicting outcome, Clin Exp Allergy, 41, 1273, 10.1111/j.1365-2222.2011.03699.x

Anagnostou, 2014, Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial, Lancet, 383, 1297, 10.1016/S0140-6736(13)62301-6

Narisety, 2014, A randomized, double-blind, placebo-controlled pilot study of sublingual versus oral immunotherapy for the treatment of peanut allergy, J Allergy Clin Immunol, 135, 1275, 10.1016/j.jaci.2014.11.005

Patriarca, 2003, Oral desensitizing treatment in food allergy: clinical and immunological results, Aliment Pharmacol Ther, 17, 459, 10.1046/j.1365-2036.2003.01468.x

Patriarca, 1998, Food allergy in children: results of a standardized protocol for oral desensitization, Hepatogastroenterology, 45, 52

Buchanan, 2007, Egg oral immunotherapy in nonanaphylactic children with egg allergy, J Allergy Clin Immunol, 119, 199, 10.1016/j.jaci.2006.09.016

Vickery, 2010, Individualized IgE-based dosing of egg oral immunotherapy and the development of tolerance, Ann Allergy Asthma Immunol, 105, 444, 10.1016/j.anai.2010.09.030

Morisset, 2007, Oral desensitization in children with milk and egg allergies obtains recovery in a significant proportion of cases. A randomized study in 60 children with cow's milk allergy and 90 children with egg allergy, Eur Ann Allergy Clin Immunol, 39, 12

Dello Iacono, 2013, Specific oral tolerance induction with raw hen's egg in children with very severe egg allergy: a randomized controlled trial, Pediatr Allergy Immunol, 24, 66, 10.1111/j.1399-3038.2012.01349.x

Meglio, 2013, Oral food desensitization in children with IgE-mediated hen's egg allergy: a new protocol with raw hen's egg, Pediatr Allergy Immunol, 24, 75, 10.1111/j.1399-3038.2012.01341.x

Itoh, 2010, Rush specific oral tolerance induction in school-age children with severe egg allergy: one year follow up, Allergol Int, 59, 43, 10.2332/allergolint.09-OA-0107

Garcia Rodriguez, 2011, Oral rush desensitization to egg: efficacy and safety, Clin Exp Allergy, 41, 1289, 10.1111/j.1365-2222.2011.03722.x

Meglio, 2004, A protocol for oral desensitization in children with IgE-mediated cow's milk allergy, Allergy, 59, 980, 10.1111/j.1398-9995.2004.00542.x

Meglio, 2008, Oral desensitization in children with immunoglobulin E-mediated cow's milk allergy–follow-up at 4 yr and 8 months, Pediatr Allergy Immunol, 19, 412, 10.1111/j.1399-3038.2007.00670.x

Zapatero, 2008, Oral desensitization in children with cow's milk allergy, J Investig Allergol Clin Immunol, 18, 389

Alvaro, 2012, Specific oral desensitization in children with IgE-mediated cow's milk allergy. Evolution in one year, Eur J Pediatr, 171, 1389, 10.1007/s00431-012-1739-z

Sanchez-Garcia, 2012, Efficacy of oral immunotherapy protocol for specific oral tolerance induction in children with cow's milk allergy, Isr Med Assoc J, 14, 43

Longo, 2008, Specific oral tolerance induction in children with very severe cow's milk-induced reactions, J Allergy Clin Immunol, 121, 343, 10.1016/j.jaci.2007.10.029

Skripak, 2008, A randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow's milk allergy, J Allergy Clin Immunol, 122, 1154, 10.1016/j.jaci.2008.09.030

Narisety, 2009, Open-label maintenance after milk oral immunotherapy for IgE-mediated cow's milk allergy, J Allergy Clin Immunol, 124, 610, 10.1016/j.jaci.2009.06.025

Pajno, 2010, Oral immunotherapy for cow's milk allergy with a weekly up-dosing regimen: a randomized single-blind controlled study, Ann Allergy Asthma Immunol, 105, 376, 10.1016/j.anai.2010.03.015

Pajno, 2013, Comparison between two maintenance feeding regimens after successful cow's milk oral desensitization, Pediatr Allergy Immunol, 24, 376, 10.1111/pai.12077

Martorell, 2011, Oral desensitization as a useful treatment in 2-year-old children with cow's milk allergy, Clin Exp Allergy, 41, 1297, 10.1111/j.1365-2222.2011.03749.x

Salmivesi, 2013, Milk oral immunotherapy is effective in school-aged children, Acta Paediatr, 102, 172, 10.1111/j.1651-2227.2012.02815.x

Keet, 2012, The safety and efficacy of sublingual and oral immunotherapy for milk allergy, J Allergy Clin Immunol, 129, 448, 10.1016/j.jaci.2011.10.023

Begin, 2014, Safety and feasibility of oral immunotherapy to multiple allergens for food allergy, Allergy Asthma Clin Immunol, 10, 1, 10.1186/1710-1492-10-1

Vickery, 2013, Peanut oral immunotherapy modifies IgE and IgG4 responses to major peanut allergens, J Allergy Clin Immunol, 131, 128, 10.1016/j.jaci.2012.10.048

Syed, 2014, Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3), J Allergy Clin Immunol, 133, 500, 10.1016/j.jaci.2013.12.1037

Chen, 1995, Peripheral deletion of antigen-reactive T cells in oral tolerance, Nature, 376, 177, 10.1038/376177a0

Begin, 2015, Changes in peanut-specific T-cell clonotype with oral immunotherapy, J Allergy Clin Immunol, 135, 1636, 10.1016/j.jaci.2015.03.010

Wasserman, 2014, Oral immunotherapy for peanut allergy: multipractice experience with epinephrine-treated reactions, J Allergy Clin Immunol Pract, 2, 91, 10.1016/j.jaip.2013.10.001

Sanchez-Garcia, 2012, Possible eosinophilic esophagitis induced by milk oral immunotherapy, J Allergy Clin Immunol, 129, 1155, 10.1016/j.jaci.2011.11.042

Ridolo, 2011, Eosinophilic esophagitis after specific oral tolerance induction for egg protein, Ann Allergy Asthma Immunol, 106, 73, 10.1016/j.anai.2010.10.010

Lucendo, 2014, Relation between eosinophilic esophagitis and oral immunotherapy for food allergy: a systematic review with meta-analysis, Ann Allergy Asthma Immunol, 113, 624, 10.1016/j.anai.2014.08.004

Nadeau, 2011, Rapid oral desensitization in combination with omalizumab therapy in patients with cow's milk allergy, J Allergy Clin Immunol, 127, 1622, 10.1016/j.jaci.2011.04.009

Schneider, 2013, A pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients, J Allergy Clin Immunol, 132, 1368, 10.1016/j.jaci.2013.09.046

Tang, 2015, Administration of a probiotic with peanut oral immunotherapy: a randomized trial, J Allergy Clin Immunol, 135, 737, 10.1016/j.jaci.2014.11.034

Noh, 2009, A pilot study of interferon-gamma-induced specific oral tolerance induction (ISOTI) for immunoglobulin E-mediated anaphylactic food allergy, J Interferon Cytokine Res, 29, 667, 10.1089/jir.2009.0001

Jagdis, 2014, Effect of ketotifen premedication on adverse reactions during peanut oral immunotherapy, Allergy Asthma Clin Immunol, 10, 36, 10.1186/1710-1492-10-36

Takahashi, 2014, New efficacy of LTRAs (montelukast sodium): it possibly prevents food-induced abdominal symptoms during oral immunotherapy, Allergy Asthma Clin Immunol, 10, 3, 10.1186/1710-1492-10-3

Lee, 2013, In vitro induction of allergen-specific interleukin-10-producing regulatory b cell responses by interferon-gamma in non-immunoglobulin e-mediated milk allergy, Allergy Asthma Immunol Res, 5, 48, 10.4168/aair.2013.5.1.48