Optimising clinical trials in acute myocardial infarction complicated by cardiogenic shock: a statement from the 2020 Critical Care Clinical Trialists Workshop
Mattia Arrigo1, Susanna Price2, David A Baran3, Janine Pöss4, Nadia Aissaoui5,6, Antoni Bayes-Genis7, Laurent Bonello8, Bruno François9, Etienne Gayat10, Martine Gilard11, Navin K Kapur12, Mahir Karakas13, Maciej Kostrubiec14,15, Pascal Leprince16, Bruno Levy17, Yves Rosenberg18, Holger Thiele4, Uwe Zeymer19, Michael O Harhay20, Alexandre Mebazaa10
1Department of Internal Medicine, Triemli Hospital Zurich and University of Zurich, Zurich, Switzerland
2Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, UK
3Advanced Heart Failure Center, Sentara Heart Hospital, Eastern Virginia Medical School, Norfolk, VA, USA
4Department of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany
5Hershey Medical Center, Heart and Vascular Institute, Critical Care Unit, Penn State University, Harrisburg, PA, USA
6Department of Critical Care, AP-HP, Hôpital Européen Georges Pompidou, Paris, France
7Heart Institute, Hospital Universitari Germans Trias i Pujol, Badalona, and Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Instituto de Salud Carlos III, Madrid, Spain
8Aix-Marseille Université, and Intensive Care Unit, Department of Cardiology, AP-HM, Hôpital Nord Marseille, and Mediterranean Association for Research and Studies in Cardiology, Marseille, France
9Department of Intensive Care, Dupuytren University Hospital and INSERM CIC-1435 and UMR-1092, Limoges, France
10Department of Anesthesia, Burn and Critical Care Medicine, AP-HP, Hôpitaux Universitaires Saint-Louis-Lariboisière, FHU PROMICE, INI-CRCT, and Université de Paris, MASCOT, INSERM, Paris, France
11Department of Cardiology, Brest University Hospital, Brest, France
12CardioVascular Center for Research and Innovation, Acute Circulatory Support Program, Interventional Research Laboratories, Boston, MA, USA
13Department of Intensive Care Medicine, University Medical Center, and Department of Cardiology, University Heart & Vascular Center Hamburg, and German Center for Cardiovascular Research (DZHK) Hamburg/Kiel/Lübeck, Germany
14Department of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland
15Mid and South Essex NHS Foundation Trust, Broomfield, UK
16Department of Cardiovascular Surgery, AP-HP, Pitié-Salpêtrère Hospital and Sorbonne University, Paris, France
17Médecine Intensive et Réanimation Brabois, CHRU de Nancy and INSERM U1116, Université de Lorraine, Nancy, France
18National Heart, Lung, and Blood Institute, Bethesda, MD USA
19Klinikum Ludwigshafen and Institut für Herzinfarktforschung, Ludwigshafen, Germany
20Palliative and Advanced Illness Research (PAIR) Center Clinical Trials Methods and Outcomes Lab, and Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
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