Optimisation of organic solvent-free polyphenol extraction from Hypericum triquetrifolium Turra using Box–Behnken experimental design and kinetics

Galanakis CM (2012) Recovery of high added-value components from food wastes: conventional, emerging technologies and commercialized applications. Trends Food Sci Technol 26:68–87

Conforti F, Loizzo M, Statti A, Menichini F (2007) Cytotoxic activity of antioxidant constituents from Hypericum triquetrifolium Turra. Nat Prod Res 21:42–46

Couladis M, Baziou P, Verykokidou E, Loukis A (2002) Antioxidant activity of polyphenols from Hypericum triquetrifolium Turra. Phytother Res 16:769–770

Apostolakis A, Grigorakis S, Makris DP (2014) Optimisation and comparative kinetics study of polyphenol extraction from olive leaves (Olea europaea) using heated water/glycerol mixtures. Separ Purif Technol 128:89–95

Lameiras P, Boudesocque L, Mouloungui Z, Renault J-H, Wieruszeski J-M, Lippens G, Nuzillard J-M (2011) Glycerol and glycerol carbonate as ultraviscous solvents for mixture analysis by NMR. J Magn Reson 212:161–168

Cacace J, Mazza G (2002) Extraction of anthocyanins and other phenolics from black currants with sulfured water. J Agric Food Chem 50:5939–5946

Makris DP, Kefalas P (2013) Characterization of polyphenolic phytochemicals in red grape pomace. Inter J Waste Resour 3:126

Makris DP, Boskou G, Andrikopoulos NK (2007) Polyphenolic content and in vitro antioxidant characteristics of wine industry and other agri-food solid waste extracts. J Food Compos Anal 20:125–132

Cavdarova M, Makris DP (2014) Extraction kinetics of phenolics from carob (Ceratonia siliqua L.) kibbles using environmentally benign solvents. Waste Biomass Valor 5:1–7

Seikova I, Simeonov E, Ivanova E (2004) Protein leaching from tomato seed—experimental kinetics and prediction of effective diffusivity. J Food Eng 61:165–171

Rakotondramasy-Rabesiaka L, Havet J-L, Porte C, Fauduet H (2010) Estimation of effective diffusion and transfer rate during the protopine extraction process from Fumaria officinalis L. Separ Purif Technol 76:126–131

Tao Y, Zhang Z, Sun D-W (2014) Kinetic modeling of ultrasound-assisted extraction of phenolic compounds from grape marc: influence of acoustic energy density and temperature. Ultrasonics Sonochem 21:1461–1469

Herodež ŠS, Hadolin M, Škerget M, Knez Ž (2003) Solvent extraction study of antioxidants from balm (Melissa officinalis) leaves. Food Chem 80:275–282

Kalogeropoulos N, Yannakopoulou K, Gioxari A, Chiou A, Makris DP (2010) Polyphenol characterization and encapsulation in β-cyclodextrin of a flavonoid-rich Hypericum perforatum (St John’s wort) extract. LWT Food Sci Technol 43:882–889

Bogdanov MG, Svinyarov I (2013) Ionic liquid-supported solid–liquid extraction of bioactive alkaloids. II. Kinetics, modeling and mechanism of glaucine extraction from Glaucium flavum Cr. (Papaveraceae). Separ Purif Technol 103:279–288

Aguilera JM (2003) Solid–liquid extraction. In: Tzia C, Liadakis G (eds) Extraction optimization in food engineering. Marcel Dekker Inc., Switzerland

Hosni K, Msaâda K, Taârit MB, Hammami M, Marzouk B (2010) Bioactive components of three Hypericum species from Tunisia: a comparative study. Ind Crops Prod 31:158–163

Silva BA, Ferreres F, Malva JO, Dias AC (2005) Phytochemical and antioxidant characterization of Hypericum perforatum alcoholic extracts. Food Chem 90:157–167

Tatsis EC, Boeren S, Exarchou V, Troganis AN, Vervoort J, Gerothanassis IP (2007) Identification of the major constituents of Hypericum perforatum by LC/SPE/NMR and/or LC/MS. Phytochemistry 68:383–393

Pinelo M, Tress AG, Pedersen M, Arnous A, Meyer AS (2007) Effect of cellulases, solvent type and particle size distribution on the extraction of chlorogenic acid and other phenols from spent coffee grounds. Am J Food Technol 2:641–651

Pilepić KH, Maleš Ž (2013) Quantitative analysis of polyphenols in eighteen Hypericum taxa. Period Biolog 115:459–462

Silva BA, Malva JO, Dias AC (2008) St. John’s Wort (Hypericum perforatum) extracts and isolated phenolic compounds are effective antioxidants in several in vitro models of oxidative stress. Food Chem 110:611–619

Altun ML, Yılmaz BS, Orhan IE, Citoglu GS (2013) Assessment of cholinesterase and tyrosinase inhibitory and antioxidant effects of Hypericum perforatum L. (St. John’s wort). Ind Crops Prod 43:87–92

Božin B, Kladar N, Grujić N, Anačkov G, Samojlik I, Gavarić N, Čonić BS (2013) Impact of origin and biological source on chemical composition, anticholinesterase and antioxidant properties of some St. John’s Wort species (Hypericum spp., Hypericaceae) from the central Balkans. Molecules 18:11733–11750

Rainha N, Lima E, Baptista J (2011) Comparison of the endemic Azorean Hypericum foliosum with other Hypericum species: antioxidant activity and phenolic profile. Nat Prod Res 25:123–135

Sagratini G, Ricciutelli M, Vittori S, Öztürk N, Öztürk Y, Maggi F (2008) Phytochemical and antioxidant analysis of eight Hypericum taxa from central Italy. Fitoterapia 79:210–213

Bariş D, Kızıl M, Aytekin Ç, Kızıl G, Yavuz M, Çeken B, Ertekin AS (2011) In vitro Antimicrobial and antioxidant activity of ethanol extract of three Hypericum and three Achillea species from Turkey. Inter J Food Prop 14:339–355

Kızıl G, Kızıl M, Çeken B, Yavuz M, Demir H (2011) Protective ability of ethanol extracts of Hypericum scabrum l. and Hypericum retusum aucher against the protein oxidation and DNA damage. Inter J Food Prop 14:339–355

Aoun M, Makris DP (2012) Binary mixtures of natural polyphenolic antioxidants with ascorbic acid: impact of interactions on the antiradical activity. Inter Food Res J 19:603–606

Karvela E, Makris DP, Karathanos V (2013) Evaluation of mixture effects in binary solutions of ascorbic acid with grape (Vitis vinifera) seed extracts using response surface methodology. Inter Food Res J 20:2193–2198