Optimal Treatment for Patients with Oligometastatic Prostate Cancer

Urologia Internationalis - Tập 106 Số 3 - Trang 217-226 - 2022
Bülent Çetin1, Chiara A. Wabl2, Özge Gümüşay2
1Division of Medical Oncology, Department of Internal Medicine, Suleyman Demirel University Faculty of Medicine, Isparta, Turkey
2UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA

Tóm tắt

Oligometastatic prostate cancer (PCa) can be defined as cancer with a limited number of metastases, typically fewer than 5 lesions, and involves lesions contained within the axial versus the appendicular skeleton. Patients can present with de novo oligometastatic, oligorecurrent, or oligoprogressive PCa. Oligometastatic PCa patients demonstrate considerable improvements in survival outcomes, with a better prognosis than patients with extensive metastatic disease. However, the management of patients that present with nonsymptomatic oligometastatic PCa remains difficult. In the oligometastatic setting, the benefit of local therapies such as prostatectomy and radiotherapy on survival outcomes is an intriguing topic; however, their impact on oncological outcomes is still unknown.

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