Opposite long-term synaptic effects of 17β-estradiol and 5α-dihydrotestosterone and localization of their receptors in the medial vestibular nucleus of rats

Brain Research Bulletin - Tập 97 - Trang 1-7 - 2013
Silvarosa Grassi1, Mariangela Scarduzio1, Roberto Panichi1, Cecilia Dall’Aglio2, Cristiano Boiti3, Vito E. Pettorossi1
1Dipartimento di Medicina Interna, Sezione di Fisiologia Umana, Università di Perugia, Via del Giochetto, I-06126 Perugia, Italy
2Dipartimento di Scienze Biopatologiche ed Igiene delle Produzioni Animali e Alimentari, Sezione di Anatomia, Laboratorio di Biotecnologie Fisiologiche, Università di Perugia, Via S. Costanzo 4, I-06100 Perugia, Italy
3Dipartimento di Scienze Biopatologiche ed Igiene delle Produzioni Animali e Alimentari, Sezione di Fisiologia Veterinaria, Laboratorio di Biotecnologie Fisiologiche, Università di Perugia, Via S. Costanzo 4, I-06100 Perugia, Italy

Tài liệu tham khảo

Andrescu, 2007, Estradiol improves cerebellar memory formation by activating estrogen receptor β, Journal of Neuroscience, 27, 10832, 10.1523/JNEUROSCI.2588-07.2007 Babalian, 1997, Central vestibular networks in the guinea-pig: functional characterization in the isolated whole brain in vitro, Neuroscience, 81, 405, 10.1016/S0306-4522(97)00069-9 Baulieu, 1998, Neurosteroids: a novel function of the brain, Psychoneuroendocrinology, 23, 963, 10.1016/S0306-4530(98)00071-7 Grassi, 2007, Neurosteroid modulation of neuronal excitability and synaptic transmission in the rat medial vestibular nuclei, European Journal of Neuroscience, 26, 23, 10.1111/j.1460-9568.2007.05645.x Grassi, 2009, Long-term potentiation in the rat medial vestibular nuclei depends on locally synthesised 17β-estradiol, Journal of Neuroscience, 29, 10779, 10.1523/JNEUROSCI.1697-09.2009 Grassi, 2010, Influence of testosterone on synaptic transmission in the rat medial vestibular nuclei: estrogenic and androgenic effects, Neuroscience, 171, 666, 10.1016/j.neuroscience.2010.09.035 Grassi, 2010, Effects of 17β-estradiol on glutamate synaptic transmission and neuronal excitability in the rat medial vestibular nuclei, Neuroscience, 165, 1100, 10.1016/j.neuroscience.2009.11.039 Grassi, 2011, Influence of sex and estrous cycle on synaptic responses of the medial vestibular nuclei in rats: role of circulating 17β-estradiol, Brain Research Bulletin, 87, 319, 10.1016/j.brainresbull.2011.11.008 Grassi, 2011, Neural 17β-estradiol facilitates long-term potentiation in the hippocampal CA1 region, Neuroscience, 192, 67, 10.1016/j.neuroscience.2011.06.078 Hamson, 2004, Distribution of androgen receptor immunoreactivity in the brainstem of male rats, Neuroscience, 127, 797, 10.1016/j.neuroscience.2004.06.006 Hojo, 2004, Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P450 17alpha and P450 aromatase localized in neurons, Proceedings of the National Academy of Sciences of the United States of America, 101, 865, 10.1073/pnas.2630225100 Hojo, 2008, Estrogen synthesis in the brain. Role on synaptic plasticity and memory, Molecular and Cellular Endocrinology, 290, 31, 10.1016/j.mce.2008.04.017 Hojo, 2009, Comparison between hippocampus-synthesized and circulation-derived sex steroids in the hippocampus, Endocrinology, 150, 5106, 10.1210/en.2009-0305 Horvath, 1999, Aromatase in developing sensory system in the rat brain, Journal of Neuroendocrinology, 11, 77, 10.1046/j.1365-2826.1999.00285.x Johnston, 1994, Ionic conductances contributing to spike depolarization and after-potentials in rat medial vestibular nucleus neurons, Journal of Physiology, 481, 61, 10.1113/jphysiol.1994.sp020419 Kimoto, 2001, Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain, Endocrinology, 142, 3578, 10.1210/en.142.8.3578 Liu, 2008, Activation of estrogen receptors-beta regulates hippocampal synaptic plasticity and improves memory, Nature Neuroscience, 11, 334, 10.1038/nn2057 Mellon, 2001, Biosynthesis and action of neurosteroids, Brain Research Reviews, 37, 3, 10.1016/S0165-0173(01)00109-6 Mukai, 2006, Hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: synaptocrinology, Neuroscience, 138, 757, 10.1016/j.neuroscience.2005.09.010 Naftolin, 1975, The formation and metabolism of estrogens in brain tissues, Advances in the Biosciences, 15, 105 Okada, 1998, Enhancement of GABA-mediated inhibition of rat medial vestibular nucleus neurons by the neurosteroid 20-hydroxyecdysone, Acta Otolaryngology, 118, 11, 10.1080/00016489850155062 Paxinos, 1986 Pettorossi, 2011, Cyclic estrogenic fluctuation influences synaptic transmission of the medial vestibular nuclei in female rats, Acta Otolaryngology, 131, 434, 10.3109/00016489.2010.536992 Robel, 1994, Neurosteroids biosynthesis and function, Trends in Endocrinology & Metabolism, 5, 1, 10.1016/1043-2760(94)90114-7 Seemungal, 2001, The endocrine system, vertigo and balance, Current Opinion in Neurology, 14, 27, 10.1097/00019052-200102000-00005 Serafin, 1991, Medial vestibular nucleus in the guinea-pig. I. Intrinsic membrane properties in brainstem slices, Experimental Brain Research, 84, 417, 10.1007/BF00231464 Simerly, 1990, Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study, Journal of Comparative Neurology, 294, 76, 10.1002/cne.902940107 Simpson, 1994, Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis, Endocrine Reviews, 15, 342 Tanaka, 2012, Continuous de novo synthesis of neurosteroids is required for normal synaptic transmission and plasticity in the dentate gyrus of the rat hippocampus, Neuropharmacology, 62, 2373, 10.1016/j.neuropharm.2012.02.007 Yamamoto, 1998, Effects of the neurosteroid dehydropiandrosterone sulphate on medial vestibular nucleus neurons, Acta Otolaryngology, 118, 185, 10.1080/00016489850183692 Yamamoto, 1998, The neurosteroid pregnenolone sulphate excites medial vestibular nucleus neurons, Acta Otolaryngology, 533, 22, 10.1080/00016489850183692