Opposite-directional sex change in functional female protandrous anemonefish, Amphiprion clarkii: effect of aromatase inhibitor on the ovarian tissue

Atz JW. Intersexuality in fishes. Academic Press; 1964.

Devlin RH, Nagahama Y. Sex determination and sex differentiation in fish: an overview of genetic, physiological, and environmental influences. Aquaculture. 2002;208:191–364.

Kobayashi Y, Nagahama Y, Nakamura M. Diversity and plasticity of sex determination and differentiation in fishes. Sex Dev. 2013;7:115–25.

Godwin JR, Thomas P. Sex change and steroid profiles in the protandrous anemonefish Amphiprion melanopus (Pomacentridae, Teleostei). Gen Comp Endocrinol. 1993;91:144–57.

Godwin J. Historical aspects of protandrous sex change in the anemonefish Amphiprion melanopus (Pomacentridae, teleostei). J Zool. 1994;232:199–213.

Nakamura M, Mariko T, Nagahama Y. Ultrastructure and in vitro Steroidogenesis of the Gonads in the Protandrous Anemonefish Amphiprion frenatus. Japan J Ichthyology. 1994;41:47–56.

Miura S, Komatsu T, Higa M, Bhandari R, Nakamura S, Nakamura M. Gonadal sex differentiation in protandrous anemone fish, Amphiprion clarkii. Fish Physiol Biochem. 2003;28:165–6.

Kobayashi Y, Horiguchi R, Miura S, Nakamura M. Sex- and tissue-specific expression of P450 aromatase (cyp19a1a) in the yellowtail clownfish, Amphiprion clarkii. Comp Biochem Phys A. 2010;155:237–44.

Fricke H, Fricke S. Monogamy and sex change by aggressive dominance in coral reef fish. Nature. 1977;266:830–2.

Moyer JT, Nakazono A. Protatidrous Hermaphroditism, in Six Species of the Anemonefish Genus Amphiprion in Japan. Jpn J Ichthyol. 1978, 25.

Fricke HW. Mating system, resource defence and sex change in the anemonefish Amphiprion akallopisos. Z Tierpsychol. 1979;50:313–26.

Paul-Prasanth B, Bhandari R, Kobayashi T, Horiguchi R, Kobayashi Y, Nakamoto M, et al. Estrogen oversees the maintenance of the female genetic program in terminally differentiated gonochorists. Sci Rep. 2013;3.

Takatsu K, Miyaoku K, Roy SR, Murono Y, Sago T, Itagaki H, et al. Induction of female-to-male sex change in adult zebrafish by aromatase inhibitor treatment. Sci Rep. 2013;3.

Lee YH, Du JL, Yueh WS, Lin BY, Huang JD, Lee CY, et al. Sex change in the protandrous black porgy, Acanthopagrus schlegeli: A review in gonadal development, estradiol, estrogen receptor, aromatase activity and gonadotropin. J Experimental Zoology. 2001;290:715–26.

Nakamura M, Bhandari RK, Higa M. The role estrogens play in sex differentiation and sex changes of fish. Fish Physiol Biochem. 2003;28:113–7.

Nakamura M, Hourigan TF, Yamauchi K, Nagahama Y, Grau EG. Histological and ultrastructural evidence for the role of gonadal steroid hormones in sex change in the protogynous wrasse Thalassoma duperrey. Environ Biol Fish. 1989;24:117–36.

Bhandari RK, Komuro H, Nakamura S, Higa M, Nakamura M. Gonadal restructuring and correlative steroid hormone profiles during natural sex change in protogynous honeycomb grouper (Epinephelus merra). Zool Sci. 2003;20:1399–404.

Higa M, Ogasawara K, Sakaguchi A, Nagahama Y, Nakamura M. Role of steriod hormones in sex change of protogynous wrasse. Fish Physiol Biochem. 2003;28:149–50.

Alam MA, Bhandari RK, Kobayashi Y, Nakamura S, Soyano K, Nakamura M. Changes in androgen-producing cell size and circulating 11-ketotestosterone level during female–male sex change of honeycomb grouper Epinephelus merra. Mol Reprod Dev. 2006;73:206–14.

Miura S, Kobayashi Y, Bhandari RK, Nakamura M. Estrogen favors the differentiation of ovarian tissues in the ambisexual gonads of anemonefish Amphiprion clarkii. J Experimental Zoology Part A. 2013;319:560–8.

Asahina K, Kambegawa A, Higashi T. Development of a microtiter plate enzyme-linked immunosorbent assay for 17alpha, 20. Beta-21-trihydroxy-4-pregnen-3-one, a teleost gonadal steroid. Fisheries Science. 1995;61:491–4.

Nozu R, Horiguchi R, Murata R, Kobayashi Y, Nakamura M. Survival of ovarian somatic cells during sex change in the protogynous wrasse, Halichoeres trimaculatus. Fish Physiol Biochem. 2013;39:47–51.

Bhandari RK, Higa M, Nakamura S, Nakamura M. Aromatase inhibitor induces complete sex change in the protogynous honeycomb grouper (Epinephelus merra). Mol Reprod Dev. 2004;67:303–7.

Bhandari RK, Komuro H, Higa M, Nakamura M. Sex inversion of sexually immature honeycomb grouper (Epinephelus merra) by aromatase inhibitor. Zool Sci. 2004;21:305–10.

Okutsu T, Suzuki K, Takeuchi Y, Takeuchi T, Yoshizaki G. Testicular germ cells can colonize sexually undifferentiated embryonic gonad and produce functional eggs in fish. Proc Natl Acad Sci U S A. 2006;103:2725–9.

Nakamura M. Morphological and physiological studies on gonadal sex differentiation in teleost fish. Aqua-BioScience Monographs. 2013;6:1–47.

Nakamura M, Kobayashi T, Chang XT, Nagahama Y. Gonadal sex differentiation in teleost fish. J Experimental Zoology. 1998;281:362–72.

Chang C-F, Lau E-L, Lin B-Y. Estradiol-17β suppresses testicular development and stimulates sex reversal in protandrous black porgy, Acanthopagrus schlegeli. Fish Physiol Biochem. 1995;14:481–8.

Chang CF, Lau EL, Lin BY. Stimulation of spermatogenesis or of sex reversal according to the dose of exogenous estradiol-17 beta in juvenile males of protandrous black porgy, Acanthopagrus schlegeli. Gen Comp Endocrinol. 1995;100:355–67.

Lee YH, Yueh WS, Du JL, Sun LT, Chang CF. Aromatase inhibitors block natural sex change and induce male function in the protandrous black porgy, Acanthopagrus schlegeli Bleeker: possible mechanism of natural sex change. Biol Reprod. 2002;66:1749–54.