One-pot three-component synthesis of quinoxaline and phenazine ring systems using Fischer carbene complexes

Priyabrata Roy1, Binay K. Ghorai
1Department of Chemistry, Bengal Engineering and Science University, Shibpur, Howrah 711103, India

Tóm tắt

One-pot three-component coupling of o-alkynylheteroaryl carbonyl derivatives with Fischer carbene complexes and dienophiles leading to the synthesis of quinoxaline and phenazine ring systems has been investigated. This involves the generation of furo[3,4-b]pyrazine and furo[3,4-b]quinoxaline as transient intermediates, which were trapped with Diels–Alder dienophiles. This is the first report on furo[3,4-b]pyrazine intermediates.

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