Oncologic outcome in surgical management of jugular paraganglioma and factors influencing outcomes

Head and Neck - Tập 35 Số 4 - Trang 527-534 - 2013
Raja Ahmad Al'konee Raja Lope Ahmad1, Shailendra Sivalingam2, Masaya Konishi3, Giuseppe Donato4, Mario Sanna5,4
1Department of Otolaryngology—Head & Neck Surgery, International Islamic University, Malaysia, Kuantan, Malaysia
2Department of Otolaryngology—Head & Neck Surgery, University of Malaya, Kuala Lumpur, Malaysia
3Department of Otolaryngology, Kansai Medical University|, Osaka, Japan
4Department of Otology and Skull Base Surgery, Gruppo Otologico, Piacenza, Italy
5Department of Otolaryngology, University of Chieti, Chieti, Italy

Tóm tắt

AbstractBackgroundThe purpose of this study was to identify the factors that may influence the management outcome in patients with jugular paragangliomas.MethodsThe surgical records of 121 cases of jugular paraganglioma (Fisch classifications C and D) were reviewed.ResultsThe average follow‐up was 88 months. Intracranial extension (ICE; Fisch classification De and Di) constitutes 55.4% of the cases. Two cases had a malignant jugular paraganglioma. Complete tumor resection was achieved in 81.8% of the cases, and there was evidence of recurrence in 4.0% from this group. Surgical tumor control was achieved in 96% of cases. Perioperative complications consisted mainly of cerebrospinal fluid leakage in 1.6% of the cases. The lower cranial nerve (CN) was preserved in 63% of the patients mainly in the cases without ICE.ConclusionThe infratemporal fossa approach type A allows for complete tumor resection with low perioperative morbidity and recurrence rates. The significant influential factors were the severity of ICE and internal carotid artery involvement. © 2012 Wiley Periodicals, Inc. Head Neck, 2013

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Head and Neck

Tập 35 Số 4

527-534

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