On the maximum likelihood method in molecular phylogenetics

Journal of Molecular Evolution - Tập 32 - Trang 443-445 - 1991
Masami Hasegawa1,2, Hirohisa Kishino1,2, Naruya Saitou3
1The Institute of Statistical Mathematics, The Graduate University for Advanced Studies, Tokyo, Japan
2Department of Statistical Science, The Graduate University for Advanced Studies, Tokyo, Japan
3Department of Anthropology, University of Tokyo, Tokyo, Japan

Tóm tắt

The efficiency of obtaining the correct tree by the maximum likelihood method (Felsenstein 1981) for inferring trees from DNA sequence data was compared with trees obtained by distance methods. It was shown that the maximum likelihood method is superior to distance methods in the efficiency particularly when the evolutionary rate differs among lineages.

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