On serum as a mitogen in intact tissue

Springer Science and Business Media LLC - Tập 31 - Trang 67-73 - 1979
Klas Norrby1, Anders Grimvall1
1Department of Pathology II and Department of Mathematics, University of Linköping, Linköping, Sweden

Tóm tắt

The mitogenic effect of serum in defined cells in organ-cultured normal intact membranous rat mesentery was studied. Serum caused a strictly concentration-dependent stimulation of proliferation in mesothelial-cell-like and fibroblast-like cells, whereas the sequence S-G2-mitosis was apparently unaffected by serum. The results support the concept that similar mitogenic mechanisms may operate in cell culture and in situ in an intact tissue.

Tài liệu tham khảo

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