Olfactory Receptors in Non-Chemosensory Organs: The Nervous System in Health and Disease
Tóm tắt
Từ khóa
Tài liệu tham khảo
Alcock, 2014, Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms, Bioessays, 36, 940, 10.1002/bies.201400071
Ansoleaga, 2013, Dysregulation of brain olfactory and taste receptors in AD, PSP, CJD and AD-related model, Neuroscience, 248, 369, 10.1016/j.neuroscience.2013.06.034
Ansoleaga, 2015, Decrease in olfactory and taste receptor expression in the dorsolateral prefrontal cortex in chronic schizophrenia, J. Psychiatr. Res., 60, 109, 10.1016/j.jpsychires.2014.09.012
Asai, 1996, Genomic structure and transcription of a murine odorant receptor gene: differential initiation of transcription in the olfactory and testicular cells, Biochem. Biophys. Res. Commun., 221, 240, 10.1006/bbrc.1996.0580
Aso, 2012, Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer’s disease, Brain Pathol., 22, 636, 10.1111/j.1750-3639.2011.00560.x
Au, 2002, Rapid insertion of GLUT2 into the rat jejunal brush-border membrane promoted by glucagon-like peptide 2, Biochem. J., 367, 247, 10.1042/bj20020393
Ay, 2014, The effect of hyperbaric conditions on olfactory functions, Undersea Hyperb. Med., 41, 203
Bakalyar, 1990, Identification of a specialized adenylyl cyclase that may mediate odorant detection, Science, 250, 1403, 10.1126/science.2255909
Baker, 2015, Olfr603, an orphan olfactory receptor, is expressed in multiple specific embryonic tissues, Gene Expr. Patterns, 19, 30, 10.1016/j.gep.2015.06.002
Barish, 2015, Mechanisms of olfactory receptor neuron specification in Drosophila, Wiley Interdiscip Rev. Dev. Biol, 4, 609, 10.1002/wdev.197
Behrens, 2006, Members of RTP and REEP gene families influence functional bitter taste receptor expression, J. Biol. Chem., 281, 20650, 10.1074/jbc.m513637200
Behrens, 2007, Gustatory expression pattern of the human TAS2R bitter receptor gene family reveals a heterogenous population of bitter responsive taste receptor cells, J. Neurosci., 27, 12630, 10.1523/jneurosci.1168-07.2007
Behrens, 2010, Oral and extraoral bitter taste receptors, Results Probl. Cell. Differ., 52, 87, 10.1007/978-3-642-14426-4_8
Belluscio, 1998, Mice deficient in G(olf) are anosmic, Neuron, 20, 69, 10.1016/s0896-6273(00)80435-3
Ben-Shaul, 2010, In vivo vomeronasal stimulation reveals sensory encoding of conspecific and allospecific cues by the mouse accessory olfactory bulb, Proc. Natl. Acad. Sci. U S A, 107, 5172, 10.1073/pnas.0915147107
Berrettini, 1998, Human G (olf) gene polymorphisms and vulnerability to bipolar disorder, Psychiatr. Genet., 8, 235, 10.1097/00041444-199808040-00006
Bertram, 2011, Genetics of Alzheimer’s disease, Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 51, 10.1002/9781444341256.ch9
Billig, 2011, Ca2+-activated Cl- currents are dispensable for olfaction, Nat. Neurosci., 14, 763, 10.1038/nn.2821
Blache, 1998, Cloning and tissue distribution of a new rat olfactory receptor-like (OL2), Biochem. Biophys. Res. Commun., 242, 669, 10.1006/bbrc.1997.8041
Blomquist, 2003, Insect Pheromone Biochemistry and Molecular Biology.
Bönigk, 1999, The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits, J. Neurosci., 19, 5332, 10.1523/JNEUROSCI.19-13-05332.1999
Borchelt, 1996, Familial Alzheimer’s disease-linked presenilin 1 variants elevate Aβ1–42/1–40 ratio in vitro and in vivo, Neuron, 17, 1005, 10.1016/s0896-6273(00)80230-5
Braak, 1991, Neuropathological staging of Alzheimer-related changes, Acta Neuropathol., 82, 239, 10.1007/bf00308809
Braak, 1999, Temporal sequence of Alzheimer’s disease-related pathology, Cerebral Cortex Vol. 14, Neurodegenerative and Age-Related Changes in Structure and Function of Cerebral Cortex, 475, 10.1007/978-1-4615-4885-0_14
Braak, 2011, Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years, J. Neuropathol. Exp. Neurol., 70, 960, 10.1097/NEN.0b013e318232a379
Branscomb, 2000, Evolution of odorant receptors expressed in human testes, Genetics, 156, 785, 10.1002/1521-1878(200009)22:9803::aid-bies53.3.co;2-b
Braun, 2007, Enterochromaffin cells of the human gut: sensors for spices and odorants, Gastroenterology, 132, 1890, 10.1053/j.gastro.2007.02.036
Breer, 2012, Gastrointestinal chemosensation: chemosensory cells in the alimentary tract, Histochem. Cell Biol., 138, 13, 10.1007/s00418-012-0954-z
Briscoe, 2013, Female behaviour drives expression and evolution of gustatory receptors in butterflies, PLoS Genet., 9, e1003620, 10.1371/journal.pgen.1003620
Brunet, 1996, General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel, Neuron, 17, 681, 10.1016/s0896-6273(00)80200-7
Buck, 1991, A novel multigene family may encode odorant receptors: a molecular basis for odor recognition, Cell, 65, 175, 10.1016/0092-8674(91)90418-x
Budka, 2011, Sporadic Creutzdfeldt-Jakob disease, Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 322, 10.1002/9781444341256.ch32
Burke, 2015, Physiological mechanisms by which non-nutritive sweeteners may impact body weight and metabolism, Physiol. Behav., 152, 381, 10.1016/j.physbeh.2015.05.036
Chen, 2006, Bitter stimuli induce Ca2+ signaling and CCK release in enteroendocrine STC-1 cells: role of L-type voltage-sensitive Ca2+ channels, Am. J. Physiol. Cell Physiol., 291, C726, 10.1152/ajpcell.00003.2006
Claudianos, 2014, Odor memories regulate olfactory receptor expression in the sensory periphery, Eur. J. Neurosci., 39, 1642, 10.1111/ejn.12539
Corvol, 2001, Gαolf is necessary for coupling D1 and A2a receptors to adenylyl cyclase in the striatum, J. Neurochem., 76, 1585, 10.1046/j.1471-4159.2001.00201.x
Dal Monte, 1991, Purification and characterization of two odorant-binding proteins from nasal tissue of rabbit and pig, Comp. Biochem. Physiol. B, 99, 445, 10.1016/0305-0491(91)90068-o
Davidson, 2011, Intake of high-intensity sweeteners alters the ability of sweet taste to signal caloric consequences: implications for the learned control of energy and body weight regulation, Q. J. Exp. Psychol. (Hove), 64, 1430, 10.1080/17470218.2011.552729
Dehkordi, 2012, Neuronal expression of bitter taste receptors and downstream signalling molecules in rat brainstem, Brain Res., 1475, 1, 10.1016/j.brainres.2012.07.038
De la Cruz, 2009, A signature of evolutionary constraint on a subset of ectopically expressed olfactory receptor genes, Mol. Biol. Evol., 26, 491, 10.1093/molbev/msn294
Depoortere, 2014, Taste receptors of the gut: emerging roles in health and disease, Gut, 63, 179, 10.1136/gutjnl-2013-305112
Dhallan, 1990, Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons, Nature, 347, 184, 10.1038/347184a0
Dhingra, 2007, Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community, Circulation, 116, 480, 10.1161/circulationaha.107.689935
Dickson, 2011, Progressive supranuclear palsy and corticobasal degeneration, Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 135, 10.1002/9781444341256.ch15
Dreyer, 1998, The area code hypothesis revisited: olfactory receptors and other related transmembrane receptors may function as the last digits in a cell surface code for assembling embryos, Proc. Natl. Acad. Sci. U S A, 95, 9072, 10.1073/pnas.95.16.9072
Drutel, 1995, Cloning of OL1, a putative olfactory receptor and its expression in the developing rat heart, Receptors Channels, 3, 33
Duvernay, 2009, Anterograde trafficking of G protein-coupled receptors: function of the C-terminal F(X)6LL motif in export from the endoplasmic reticulum, Mol. Pharmacol., 75, 751, 10.1124/mol.108.051623
Duvernay, 2004, A conserved motif for the transport of G protein-coupled receptors from the endoplasmic reticulum to the cell surface, J. Biol. Chem., 279, 30741, 10.1074/jbc.M313881200
Duyckaerts, 2011, Neuropathology of Alzheimer’s disease and variants, Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 62, 10.1002/9781444341256.ch10
Dyer, 2005, Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells, Biochem. Soc. Trans., 33, 302, 10.1042/bst0330302
Eckmeier, 2014, Noradrenergic plasticity of olfactory sensory neuron inputs to the main olfactory bulb, J. Neurosci., 34, 15234, 10.1523/JNEUROSCI.0551-14.2014
Egan, 2008, Taste cells of the gut and gastrointestinal chemosensation, Mol. Interv., 8, 78, 10.1124/mi.8.2.5
Feingold, 1999, An olfactory receptor gene is located in the extended human β-globin gene cluster and is expressed in erythroid cells, Genomics, 61, 15, 10.1006/geno.1999.5935
Feinstein, 2004, Axon guidance of mouse olfactory sensory neurons by odorant receptors and the β2 adrenergic receptor, Cell, 117, 833, 10.1016/j.cell.2004.05.013
Feinstein, 2004, A contextual model for axonal sorting into glomeruli in the mouse olfactory system, Cell, 117, 817, 10.1016/j.cell.2004.05.011
Feldmesser, 2006, Widespread ectopic expression of olfactory receptor genes, BMC Genomics, 7, 121, 10.1186/1471-2164-7-121
Ferreira, 2014, Silencing of odorant receptor genes by G protein βγ signaling ensures the expression of one odorant receptor per olfactory sensory neuron, Neuron, 81, 847, 10.1016/j.neuron.2014.01.001
Ferrer, 2012, Defining Alzheimer as a common age-related neurodegenerative process not inevitably leading to dementia, Prog. Neurobiol., 97, 38, 10.1016/j.pneurobio.2012.03.005
Ferrer, 2009, Early involvement of the cerebral cortex in Parkinson’s disease: convergence of multiple metabolic defects, Prog. Neurobiol., 88, 89, 10.1016/j.pneurobio.2009.02.004
Ferrer, 2012, Neurochemistry and the non-motor aspects of PD, Neurobiol. Dis., 46, 508, 10.1016/j.nbd.2011.10.019
Ferrer, 2011, Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease, J. Neural Transm. (Vienna), 118, 821, 10.1007/s00702-010-0482-8
Firestein, 1991, Activation of the sensory current in salamander olfactory receptor neurons depends on a G protein-mediated cAMP second messenger system, Neuron, 6, 825, 10.1016/0896-6273(91)90178-3
Flegel, 2013, Expression profile of ectopic olfactory receptors determined by deep sequencing, PLoS One, 8, e55368, 10.1371/journal.pone.0055368
Flower, 1996, The lipocalin protein family: structure and function, Biochem. J., 318, 1, 10.1042/bj3180001
Fowler, 2015, Diet soda intake is associated with long-term increases in waist circumference in a biethnic cohort of older adults: the San Antonio Longitudinal Study of Aging, J. Am. Geriatr. Soc., 63, 708, 10.1111/jgs.13376
Fukuda, 2006, Developmental expression patterns of testicular olfactory receptor genes during mouse spermatogenesis, Genes Cells, 11, 71, 10.1111/j.1365-2443.2005.00915.x
Fukuda, 2004, Functional characterization of a mouse testicular olfactory receptor and its role in chemosensing and in regulation of sperm motility, J. Cell Sci., 117, 5835, 10.1242/jcs.01507
Garcia-Esparcia, 2013, Functional genomics reveals dysregulation of cortical olfactory receptors in Parkinson’s disease: novel putative chemoreceptors in the human brain, J. Neuropathol. Exp. Neurol., 72, 524, 10.1097/NEN.0b013e318294fd76
Garibotti, 1995, Porcine VEG proteins and tear prealbumin, Chem. Senses, 20, 69, 10.1093/chemse/20.1.69
Gilad, 2005, A comparison of the human and chimpanzee olfactory receptor gene repertoires, Genome Res., 15, 224, 10.1101/gr.2846405
Gimelbrant, 2001, Olfactory receptor trafficking involves conserved regulatory steps, J. Biol. Chem., 276, 7285, 10.1074/jbc.m005433200
Gimelbrant, 2004, Selective pressures on the olfactory receptor repertoire since the human-chimpanzee divergence, Proc. Natl. Acad. Sci. U S A, 101, 9019, 10.1073/pnas.0401566101
Glasgow, 1995, Tear lipocalins bind a broad array of lipid ligands, Curr. Eye Res., 14, 363, 10.3109/02713689508999934
Glusman, 2000a, The olfactory receptor gene superfamily: data mining, classification and nomenclature, Mamm. Genome, 11, 1016, 10.1007/s003350010196
Glusman, 2000b, Sequence, structure and evolution of a complete human olfactory receptor gene cluster, Genomics, 63, 227, 10.1006/geno.1999.6030
Go, 2008, Similar numbers but different repertoires of olfactory receptor genes in humans and chimpanzees, Mol. Biol. Evol., 25, 1897, 10.1093/molbev/msn135
Godfrey, 2004, The mouse olfactory receptor gene family, Proc. Natl. Acad. Sci. U S A, 101, 2156, 10.1073/pnas.0308051100
Goto, 2001, Expression of a testis-specific member of the olfactory receptor gene family in human primordial germ cells, Mol. Hum. Reprod., 7, 553, 10.1093/molehr/7.6.553
Griffin, 2009, MOR23 promotes muscle regeneration and regulates cell adhesion and migration, Dev. Cell, 17, 649, 10.1016/j.devcel.2009.09.004
Grison, 2014, Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules, BMC Genomics, 15, 729, 10.1186/1471-2164-15-729
Gu, 2014, Chemosensory functions for pulmonary neuroendocrine cells, Am. J. Respir. Cell Mol. Biol., 50, 637, 10.1165/rcmb.2013-0199OC
Gu, 2015, Bitter taste receptor mTas2r105 is expressed in small intestinal villus and crypts, Biochem. Biophys. Res. Commun., 463, 934, 10.1016/j.bbrc.2015.06.038
Guiraudie-Capraz, 2005, Biochemical and chemical supports for a transnasal olfactory continuity through sow maternal fluids, Chem. Senses, 30, 241, 10.1093/chemse/bji020
Haga, 2010, The male mouse pheromone ESP1 enhances female sexual receptive behaviour through a specific vomeronasal receptor, Nature, 466, 118, 10.1038/nature09142
Hague, 2004, The N terminus of the human α1D-adrenergic receptor prevents cell surface expression, J. Pharmacol. Exp. Ther., 309, 388, 10.1124/jpet.103.060509
Halatchev, 2005, Peripheral administration of PYY(3–36) produces conditioned taste aversion in mice, Cell Metab., 1, 159, 10.1016/j.cmet.2005.02.003
Hallem, 2006, Insect odor and taste receptors, Annu. Rev. Entomol., 51, 113, 10.1146/annurev.ento.51.051705.113646
Hamzic, 2013, Immune-induced expression of lipocain-2 in brain endothelial cells: relationship with interleukin-6, cyclooxygenassse-2 and the febrile response, J. Neuroendocrinol., 25, 271, 10.1111/jne.12000
Hayden, 2014, A cluster of olfactory receptor genes linked to frugivory in bats, Mol. Biol. Evol., 31, 917, 10.1093/molbev/msu043
Head, 2009, Sporadic Creutzfeldt-Jakob disease: discrete subtypes or a spectrum of the disease, Brain, 132, 2627, 10.1093/brain/awp225
Hervé, 2011, Identification of a specific assembly of the g protein golf as a critical and regulated module of dopamine and adenosine-activated cAMP pathways in the striatum, Front. Neuroanat., 5, 48, 10.3389/fnana.2011.00048
Heydel, 2010, UDP-glucuronosyltransferases (UGTs) in neuro-olfactory tissues: expression, regulation and function, Drug Metab. Rev., 42, 74, 10.3109/03602530903208363
Höfer, 1996, Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin, Proc. Natl. Acad. Sci. U S A, 93, 6631, 10.1073/pnas.93.13.6631
Holy, 2000, Responses of vomeronasal neurons to natural stimuli, Science, 289, 1569, 10.1126/science.289.5484.1569
Hoover, 2013, Evolution of olfactory receptors, Methods Mol. Biol., 1003, 241, 10.1007/978-1-62703-377-0_18
Houlden, 2012, The genetics and neuropathology of Parkinson’s disease, Acta Neuropathol., 124, 325, 10.1007/s00401-012-1013-5
Hsu, 2008, Structural characterization of sulfated steroids that activate mouse pheromone-sensing neurons, Biochemistry, 47, 14009, 10.1021/bi801392j
Hughes, 2014, Loss of olfactory receptor function in hominin evolution, PLoS One, 9, e84714, 10.1371/journal.pone.0084714
Ihara, 2013, Chemosensory signals and their receptors in the olfactory neural system, Neuroscience, 254, 45, 10.1016/j.neuroscience.2013.08.063
Ishimaru, 2009, Transient receptor potential (TRP) channels and taste sensation, J. Dent. Res., 88, 212, 10.1177/0022034508330212
Itakura, 2006, Expression of Golf in the rat placenta: possible implication in olfactory receptor transduction, Placenta, 27, 103, 10.1016/j.placenta.2004.12.006
Iwatsuki, 2012, Sense of taste in the gastrointestinal tract, J. Pharmacol. Sci., 118, 123, 10.1254/jphs.11r08cp
Jacquier, 2006, Characterization of an extended receptive ligand repertoire of the human olfactory receptor OR17–40 comprising structurally related compounds, J. Neurochem., 97, 537, 10.1111/j.1471-4159.2006.03771.x
Jang, 2007, Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1, Proc. Natl. Acad. Sci. U S A, 104, 15069, 10.1073/pnas.0706890104
Jang, 2013, Secreted protein lipocalin-2 promotes microglial M1 polarization, FASEB J., 27, 1176, 10.1096/fj.12-222257
Jellinger, 2011, Parkinson’s disease, Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 194, 10.1002/9781444341256.ch21
Jin, 2014, Lipocalin-2 deficiency attenuates neuroinflammation and brain injury after transient middle cerebral artery occlusion in mice, J. Cereb. Blood Flow Metab., 34, 1306, 10.1038/jcbfm.2014.83
Jones, 1989, Golf: an olfactory neuron specific-G protein involved in odorant signal transduction, Science, 244, 790, 10.1126/science.2499043
Jungnickel, 2001, Trp2 regulates entry of Ca2+ into mouse sperm triggered by egg ZP3, Nat. Cell Biol., 3, 499, 10.1038/35074570
Juntti, 2010, The androgen receptor governs the execution, but not programming, of male sexual and territorial behaviours, Neuron, 66, 260, 10.1016/j.neuron.2010.03.024
Kanageswaran, 2015, Deep sequencing of the murine olfactory receptor neuron transcriptome, PLoS One, 10, e0113170, 10.1371/journal.pone.0113170
Kang, 2015, Olfactory receptor Olfr544 responding to azelaic acid regulates glucagon secretion in α-cells of mouse pancreatic islets, Biochem. Biophys. Res. Commun., 460, 616, 10.1016/j.bbrc.2015.03.078
Kang, 2012, Olfactory receptors in non-chemosensory tissues, BMB Rep., 45, 612, 10.5483/bmbrep.2012.45.11.232
Kato, 2009, Mammalian olfactory receptors: pharmacology, G protein coupling and desensitization, Cell Mol. Life Sci., 66, 3743, 10.1007/s00018-009-0111-6
Keller, 2007, Genetic variation in a human odorant receptor alters odour perception, Nature, 449, 468, 10.1038/nature06162
Kendig, 2014, Activation of the umami taste receptor (T1R1/T1R3) initiates the peristaltic reflex and pellet propulsion in the distal colon, Am. J. Physiol. Gastrointest. Liver Physiol., 307, G1100, 10.1152/ajpgi.00251.2014
Kerr, 2008, Ric-8B interacts with Gαolf and Gγ13 and co-localizes with Gαolf, Gβ1 and Gγ13 in the cilia of olfactory sensory neurons, Mol. Cell Neurosci., 38, 341, 10.1016/j.mcn.2008.03.006
Khafizov, 2007, Ligand specificity of odorant receptors, J. Mol. Model., 13, 401, 10.1007/s00894-006-0160-9
Kim, 2015a, Expression of human olfactory receptor 10J5 in heart aorta, coronary artery and endothelial cells and its functional role in angiogenesis, Biochem. Biophys. Res. Commun., 460, 404, 10.1016/j.bbrc.2015.03.046
Kim, 2015b, Odorant stimulation promotes survival of rodent olfactory receptor neurons via PI3K/Akt activation and Bcl-2 expression, Mol. Cells, 38, 535, 10.14348/molcells.2015.0038
Kimchi, 2007, A functional circuit underlying male sexual behaviour in the female mouse brain, Nature, 448, 1009, 10.1038/nature06089
Kludt, 2015, Integrating temperature with odor processing in the olfactory bulb, J. Neurosci., 35, 7892, 10.1523/JNEUROSCI.0571-15.2015
Knopman, 2011, Clinical aspects of Alzheimer’s disease, Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 39, 10.1002/9781444341256.ch8
Kumar, 2014, Mutations in GNAL: a novel cause of craniocervical dystonia, JAMA Neurol., 71, 490, 10.1001/jamaneurol.2013.4677
Kwon, 2009, Ca extrusion by NCX is compromised in olfactory sensory neurons of OMP mice, PLoS One, 4, e4260, 10.1371/journal.pone.0004260
Laurin, 2008, Investigation of the G protein subunit Gαolf gene (GNAL) in attention deficit/hyperactivity disorder, J. Psychiatr. Res., 42, 117, 10.1016/j.jpsychires.2006.10.010
Leclerc, 2002, Glucuronidation of odorant molecules in the rat olfactory system: activity, expression and age-linked modifications of UDP-glucuronosyltransferase isoforms, UGT1A6 and UGT2A1 and relation to mitral cell activity, Brain Res. Mol. Brain Res., 107, 201, 10.1016/s0169-328x(02)00455-2
Le Danvic, 2009, Natural ligands of porcine olfactory binding proteins, J. Chem. Ecol., 35, 741, 10.1007/s10886-009-9645-1
Lee, 2011, Lipocalin-2 Is a chemokine inducer in the central nervous system: role of chemokine ligand 10 (CXCL10) in lipocalin-2-induced cell migration, J. Biol. Chem., 286, 43855, 10.1074/jbc.M111.299248
Leinders-Zufall, 2014, A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons, J. Neurosci., 34, 5121, 10.1523/JNEUROSCI.0186-14.2014
Leypold, 2002, Altered sexual and social behaviors in trp2 mutant mice, Proc. Natl. Acad. Sci. U S A, 99, 6376, 10.1073/pnas.082127599
Li, 2015, Aversion and attraction through olfaction, Curr. Biol., 25, R120, 10.1016/j.cub.2014.11.044
Li, 2013a, Heterotrimeric G protein subunit Gγ13 is critical to olfaction, J. Neurosci., 33, 7975, 10.1523/JNEUROSCI.5563-12.2013
Li, 2013b, Activation of olfactory receptors on mouse pulmonary macrophages promotes monocyte chemotactic protein-1 production, PLoS One, 8, e80148, 10.1371/journal.pone.0080148
Liberles, 2014, Mammalian pheromones, Annu. Rev. Physiol., 76, 151, 10.1146/annurev-physiol-021113-170334
Liman, 1994, A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMP, Neuron, 13, 611, 10.1016/0896-6273(94)90029-9
Lowe, 2015, Dementia, Greenfield’s Neuropathology, 858
Lowe, 1989, Adenylate cyclase mediates olfactory transduction for a wide variety of odorants, Proc. Natl. Acad. Sci. U S A, 86, 5641, 10.1073/pnas.86.14.5641
Luo, 2002, Impaired olfactory behavior in mice deficient in the α subunit of G(o), Brain Res., 941, 62, 10.1016/s0006-8993(02)02566-0
Luo, 2003, Encoding pheromonal signals in the accessory olfactory bulb of behaving mice, Science, 299, 1196, 10.1126/science.1082133
Lutsey, 2008, Dietary intake and the development of the metabolic syndrome: the atherosclerosis risk in communities study, Circulation, 117, 754, 10.1161/CIRCULATIONAHA.107.716159
Mace, 2007, Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2, J. Physiol., 582, 379, 10.1113/jphysiol.2007.130906
Mackenzie, 2005a, Nomenclature up-date for the mammalian UDP glycosyltransferase (UGT) gene superfamily, Pharmacogenet. Genomics, 15, 677, 10.1097/01.fpc.0000173483.13689.56
Mackenzie, 2005b, Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosyltransferases, Toxicol. Appl. Pharmacol., 207, 77, 10.1016/j.taap.2004.12.026
Malnic, 2007, Searching for the ligands of odorant receptors, Mol. Neurobiol., 35, 175, 10.1007/s12035-007-0013-2
Malnic, 2004, The human olfactory receptor gene family, Proc. Natl. Acad. Sci. U S A, 101, 2584, 10.1073/pnas.0307882100
Malnic, 2010, Odorant receptors, The Neurobiology of Olfaction
Manteniotis, 2013, Comprehensive RNA-Seq expression analysis of sensory ganglia with a focus on ion channels and GPCRs in trigeminal ganglia, PLoS One, 8, e79523, 10.1371/journal.pone.0079523
Marchese, 1998, Lipocalins of boar salivary glands binding odours and pheromones, Eur. J. Biochem., 252, 563, 10.1046/j.1432-1327.1998.2520563.x
Margolskee, 2007, T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1, Proc. Natl. Acad. Sci. U S A, 104, 15075, 10.1073/pnas.0706678104
Martin, 2011, Environmental temperature modulates olfactory reception in Drosophila melanogaster, J. Insect Physiol., 57, 1631, 10.1016/j.jinsphys.2011.08.016
Mast, 2010, The TRPC2 channel forms protein-protein interactions with homer and RTP in the rat vomeronasal organ, BMC Neurosci., 11, 61, 10.1186/1471-2202-11-61
Mombaerts, 1999, Molecular biology of odorant receptors in vertebrates, Annu. Rev. Neurosci., 22, 487, 10.1146/annurev.neuro.22.1.487
Mombaerts, 2004, Genes and ligands for odorant, vomeronasal and taste receptors, Nat. Rev. Neurosci., 5, 263, 10.1038/nrn1365
Nakamura, 1987, A cyclic nucleotide-gated conductance in olfactory receptor cilia, Nature, 325, 442, 10.1038/325442a0
Nam, 2014, Lipocalin-2 protein deficiency ameliorates experimental autoimmune encephalomyelitis: the pathogenic role of lipocalin-2 in the central nervous system and peripheral lymphoid tissues, J. Biol. Chem., 289, 16773, 10.1074/jbc.M113.542282
Natarajan, 2015, Olfaction in the kidney: ‘smelling’ gut microbial metabolites, Exp. Physiol., 101, 478, 10.1113/ep085285
Nef, 1997, Olfaction: transient expression of a putative odorant receptor in the avian notochord, Proc. Natl. Acad. Sci. U S A, 94, 4766, 10.1073/pnas.94.9.4766
Neuhaus, 2009, Activation of an olfactory receptor inhibits proliferation of prostate cancer cells, J. Biol. Chem., 284, 16218, 10.1074/jbc.M109.012096
Niimura, 2012, Olfactory receptor multigene family in vertebrates: from the viewpoint of evolutionary genomics, Curr. Genomics, 13, 103, 10.2174/138920212799860706
Niimura, 2014, Extreme expansion of the olfactory receptor gene repertoire in African elephants and evolutionary dynamics of orthologous gene groups in 13 placental mammals, Genome Res., 24, 1485, 10.1101/gr.169532.113
Niimura, 2003, Evolution of olfactory receptor genes in the human genome, Proc. Natl. Acad. Sci. U S A, 100, 12235, 10.1073/pnas.1635157100
Niimura, 2005, Comparative evolutionary analysis of olfactory receptor gene clusters between humans and mice, Gene, 346, 13, 10.1016/j.gene.2004.09.025
Nodari, 2008, Sulfated steroids as natural ligands of mouse pheromone-sensing neurons, J. Neurosci., 28, 6407, 10.1523/jneurosci.1425-08.2008
Olender, 2004, The olfactory receptor universe–from whole genome analysis to structure and evolution, Genet. Mol. Res., 3, 545
Otaki, 2004, Odorant receptor expression in the mouse cerebral cortex, J. Neurobiol., 58, 315, 10.1002/neu.10272
Pace, 1985, Odorant-sensitive adenylate cyclase may mediate olfactory reception, Nature, 316, 255, 10.1038/316255a0
Paolini, 1998, Amino acid sequence, posttranslational modifications, binding and labelling of porcine odorant-binding protein, Chem. Senses, 23, 689, 10.1093/chemse/23.6.689
Parchi, 2011, Genetic Creutzfeldt-Jakob disease, Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 322, 10.1002/9781444341256.ch33
Parchi, 2009, Incidence and spectrum of sporadic Creutzfledt-Jakob disease variants with mixed phenotypes and co-occurrence of PrPsc types: an updated classification, Acta Neuropathol., 118, 659, 10.1007/s00401-009-0585-1
Parmentier, 1992, Expression of members of the putative olfactory receptor gene family in mammalian germ cells, Nature, 355, 453, 10.1038/355453a0
Pelosi, 1990, Odorant binding proteins in vertebrates and insects: similarities and possible common functions, Chem. Senses, 15, 205, 10.1093/chemse/15.2.205
Pepino, 2015, Metabolic effects of non-nutritive sweeteners, Physiol. Behav., 152, 450, 10.1016/j.physbeh.2015.06.024
Perricone, 2013, Smell and autoimmunity: a comprehensive review, Clin. Rev. Allergy Immunol., 45, 87, 10.1007/s12016-012-8343-x
Persuy, 2015, Mammalian olfactory receptors: molecular mechanisms of odorant detection, 3D-modeling and structure-activity relationships, Prog. Mol. Biol. Transl. Sci., 130, 1, 10.1016/bs.pmbts.2014.11.001
Pevsner, 1988, Molecular cloning of odorant-binding protein: member of a ligand carrier family, Science, 241, 336, 10.1126/science.3388043
Pevsner, 1986, Odorant-binding protein: localization to nasal glands and secretions, Proc. Natl. Acad. Sci. U S A, 83, 4942, 10.1073/pnas.83.13.4942
Picone, 2014, Taste and odorant receptors of the coelacanth–a gene repertoire in transition, J. Exp. Zool. B Mol. Dev. Evol., 322, 403, 10.1002/jez.b.22531
Pierce, 2007, Overeating by young obesity-prone and lean rats caused by tastes associated with low energy foods, Obesity (Silver Spring), 15, 1969, 10.1038/oby.2007.235
Pluznick, 2013, Renal and cardiovascular sensory receptors and blood pressure regulation, Am. J. Physiol. Renal. Physiol., 305, F439, 10.1152/ajprenal.00252.2013
Pluznick, 2014, Extra sensory perception: the role of Gpr receptors in the kidney, Curr. Opin. Nephrol. Hypertens., 23, 507, 10.1097/MNH.0000000000000048
Pluznick, 2013, Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation, Proc. Natl. Acad. Sci. U S A, 110, 4410, 10.1073/pnas.1215927110
Pluznick, 2009, Functional expression of the olfactory signaling system in the kidney, Proc. Natl. Acad. Sci. U S A, 106, 2059, 10.1073/pnas.0812859106
Pronin, 2014, Expression of olfactory signaling genes in the eye, PLoS One, 9, e96435, 10.1371/journal.pone.0096435
Pyrski, 2007, Sodium/calcium exchanger expression in the mouse and rat olfactory systems, J. Comp. Neurol., 501, 944, 10.1002/cne.21290
Quignon, 2005, The dog and rat olfactory receptor repertoires, Genome Biol., 6, R83, 10.1186/gb-2005-6-10-r83
Quintela, 2013, Analysis of the effects of sex hormone background on the rat choroid plexus transcriptome by cDNA microarrays, PLoS One, 8, e60199, 10.1371/journal.pone.0060199
Rajkumar, 2014, Identification and characterization of novel renal sensory receptors, PLoS One, 9, e111053, 10.1371/journal.pone.0111053
Raskin, 2009, Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses, J. Neurosci., 29, 4461, 10.1523/JNEUROSCI.0296-09.2009
Reimann, 2012, G-protein-coupled receptors in intestinal chemosensation, Cell Metab., 15, 421, 10.1016/j.cmet.2011.12.019
Ren, 2009, Sweet taste signalling functions as a hypothalamic glucose sensor, Front. Integr. Neurosci., 3, 12, 10.3389/neuro.07.012.2009
Revesz, 2015, Extrapyramidal diseases of movement, Greenfield’s Neuropathology, 740
Riveron, 2013, Transcriptional basis of the acclimation to high environmental temperature at the olfactory receptor organs of Drosophila melanogaster, BMC Genomics, 14, 259, 10.1186/1471-2164-14-259
Rizvanovic, 2013, Olfactory discrimination ability of Asian elephants (Elephas maximus) for structurally-related odorants, Chem. Senses, 38, 107, 10.1093/chemse/bjs097
Robertson, 1993, Extraction, characterization and binding analysis of two pheromonally active ligands associated with major urinary protein of the house mouse (Mus musculus), J. Chem. Ecol., 19, 1405, 10.1007/BF00984885
Rouquier, 2000, The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates, Proc. Natl. Acad. Sci. U S A, 97, 2870, 10.1073/pnas.040580197
Rouquier, 2007, Olfactory receptor gene repertoires in mammals, Mutat. Res., 616, 95, 10.1016/j.mrfmmm.2006.11.012
Rouquier, 1998, Distribution of olfactory receptor genes in the human genome, Nat. Genet., 18, 243, 10.1038/ng0398-243
Rozengurt, 2006, Taste receptors in the gastrointestinal tract. I. Bitter taste receptors and α-gustducin in the mammalian gut, Am. J. Physiol. Gastrointest. Liver Physiol., 291, G171, 10.1152/ajpgi.00073.2006
Rozengurt, 2006, Colocalization of the α-subunit of gustducin with PYY and GLP-1 in L cells of human colon, Am. J. Physiol. Gastrointest. Liver Physiol., 291, G792, 10.1152/ajpgi.00074.2006
Ruiz-DeDiego, 2015, Dopaminergic regulation of olfactory G-protein subunit expression in the striatum, Mov. Disord., 30, 1039, 10.1002/mds.26197
Saidu, 2009, Role of plasma membrane calcium ATPases in calcium clearance from olfactory sensory neurons, Chem. Senses, 34, 349, 10.1093/chemse/bjp008
Saito, 2006, The functional properties of mammalian odorant receptors, Chem. Senses, 31, A65
Saito, 2004, RTP family members induce functional expression of mammalian odorant receptors, Cell, 119, 679, 10.1016/j.cell.2004.11.021
Sanz, 2005, Comparison of odorant specificity of two human olfactory receptors from different phylogenetic classes and evidence for antagonism, Chem. Senses, 30, 69, 10.1093/chemse/bji002
Scaloni, 2011, Purification, cloning and characterisation of odorant- and pheromone-binding proteins from pig nasal epithelium, Cell Mol. Life Sci., 58, 823, 10.1007/pl00000903
Schmiedeberg, 2007, Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2, J. Struct. Biol., 159, 400, 10.1016/j.jsb.2007.04.013
Schneider, 2015, Clinical and pathological features of Parkinson’s disease, Curr. Top. Behav. Neurosci., 22, 205, 10.1007/7854_2014_317
Serrano-Pozo, 2011, Neuropathological alterations in Alzheimer’s disease, Cold Spring Harb. Perspect. Med., 1, a006189, 10.1101/cshperspect.a006189
Shaw, 2011, Olfactory copy number association with age at onset of Alzheimer disease, Neurology, 76, 1302, 10.1212/WNL.0b013e318221c187
Shirazi-Beechey, 2014, Role of nutrient-sensing taste 1 receptor (T1R) family members in gastrointestinal chemosensing, Br. J. Nutr., 111, S8, 10.1017/s0007114513002286
Shirokova, 2005, Identification of specific ligands for orphan olfactory receptors, J. Biol. Chem., 280, 11807, 10.1074/jbc.m411508200
Singer, 1986, Purification and analysis of a proteinaceous aphrodisiac pheromone from hamster vaginal discharge, J. Biol. Chem., 28, 13323, 10.1016/S0021-9258(18)69307-X
Singh, 2011, Functional bitter taste receptors are expressed in brain cells, Biochem. Biophys. Res. Commun., 406, 146, 10.1016/j.bbrc.2011.02.016
Sklar, 1986, The odorant-sensitive adenylate cyclase of olfactory receptor cells, J. Biol. Chem., 261, 15538, 10.1016/S0021-9258(18)66747-X
Spehr, 2003, Identification of testicular odorant receptor mediating human sperm chemotaxis, Science, 299, 2054, 10.1126/science.1080376
Stephan, 2009, ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification, Proc. Natl. Acad. Sci. U S A, 106, 11776, 10.1073/pnas.0903304106
Stephan, 2011, The Na+/Ca2+ exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response, Nat. Neurosci., 15, 131, 10.1038/nn.2943
Sternini, 2008, Enteroendocrine cells: a site of ‘taste’ in gastrointestinal chemosensing, Curr. Opin. Endocrinol. Diabetes Obes., 15, 73, 10.1097/MED.0b013e3282f43a73
Stopková, 2014, Complementary roles of mouse lipocalins in chemical communication and immunity, Biochem. Soc. Trans., 42, 893, 10.1042/BST20140053
Stowers, 2002, Loss of sex discrimination and male-male aggression in mice deficient for TRP2, Science, 295, 1493, 10.1126/science.1069259
Stowers, 2010, Sexual dimorphism in olfactory signalling, Curr. Opin. Neurobiol., 20, 770, 10.1016/j.conb.2010.08.015
Swartz, 2012, Up-regulation of intestinal type 1 taste receptor 3 and sodium glucose luminal transporter-1 expression and increased sucrose intake in mice lacking gut microbiota, Br. J. Nutr., 107, 621, 10.1017/S0007114511003412
Syme, 2006, Caveolin-1 regulates cellular trafficking and function of the glucagon-like peptide 1 receptor, Mol. Endocrinol., 20, 3400, 10.1210/me.2006-0178
Taoka, 2006, Golf protein levels in rat striatum are increased by chronic antidepressant administration and decreased by olfactory bulbectomy, Life Sci., 79, 462, 10.1016/j.lfs.2006.01.033
Thal, 2002, Phases of β-amyloid deposition in the human brain and its relevance for the development of AD, Neurology, 58, 1791, 10.1212/wnl.58.12.1791
Tukey, 2000, Human UDP-glucuronosyltransferases: metabolism, expression and disease, Annu. Rev. Pharmacol. Toxicol., 40, 581, 10.1146/annurev.pharmtox.40.1.581
van Avesaat, 2015, Intraduodenal infusion of a combination of tastants decreases food intake in humans, Am. J. Clin. Nutr., 102, 729, 10.3945/ajcn.115.113266
Vanderhaeghen, 1997, Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome, Biochem. Biophys. Res. Commun., 237, 283, 10.1006/bbrc.1997.7043
Vassalli, 2002, Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb, Neuron, 35, 681, 10.1016/s0896-6273(02)00793-6
Vegezzi, 2014, Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract, PLoS One, 9, e107732, 10.1371/journal.pone.0107732
Veitinger, 2011, Chemosensory Ca2+ dynamics correlate with diverse behavioral phenotypes in human sperm, J. Biol. Chem., 286, 17311, 10.1074/jbc.m110.211524
Vemula, 2013, Role of Gα(olf) in familial and sporadic adult-onset primary dystonia, Hum. Mol. Genet., 22, 2510, 10.1093/hmg/ddt102
Vogt, 1985, Kinetic properties of a sex pherpomone-degrading enzyme: the sensillar esterase of Anthereacea polyphemus, Proc. Natl. Acad. Sci. U S A, 82, 8827, 10.1073/pnas.82.24.8827
Vogt, 1991, Molecular cloning and sequencing of general odorant-binding proteins GOBP1 and GOBP2 from the tobacco hawk moth Manduca sexta: comparison with other insect OBPs and their signal peptides, J. Neurosci., 11, 2972, 10.1523/JNEUROSCI.11-10-02972.1991
Voigt, 2015, Trans-synaptic tracing from taste receptor cells reveals local taste receptor gene expression in gustatory ganglia and brain, J. Neurosci., 35, 9717, 10.1523/JNEUROSCI.0381-15.2015
Von Dannecker, 2005, Ric-8B, an olfactory putative GTP exchange factor, amplifies signal transduction through the olfactory-specific G-protein Gαolf, J. Neurosci., 25, 3793, 10.1523/jneurosci.4595-04.2005
Von Dannecker, 2006, Ric-8B promotes functional expression of odorant receptors, Proc. Natl. Acad. Sci. U S A, 103, 9310, 10.1073/pnas.0600697103
Walensky, 1995, Odorant receptors and desensitization proteins co-localize in mammalian sperm, Mol. Med., 1, 130, 10.1007/BF03401561
Walensky, 1998, Two novel odorant receptor families expressed in spermatids undergo 5’-splicing, J. Biol. Chem., 273, 9378, 10.1074/jbc.273.16.9378
Ward, 2015, Toll receptors instruct axon and dendrite targeting and participate in synaptic partner matching in a Drosophila olfactory circuit, Neuron, 85, 1013, 10.1016/j.neuron.2015.02.003
Weber, 2002, Olfactory receptor expressed in ganglia of the autonomic nervous system, J. Neurosci. Res., 68, 176, 10.1002/jnr.10164
Wetzel, 1999, Specificity and sensitivity of a human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus laevis oocytes, J. Neurosci., 19, 7426, 10.1523/JNEUROSCI.19-17-07426.1999
Wicher, 2015, Olfactory signaling in insects, Prog. Mol. Biol. Transl. Sci., 130, 37, 10.1016/bs.pmbts.2014.11.002
Wilson, 2006, Learning to Smell: Olfactory Perception from Neurobiology to Behaviour, 10.1353/book.3242
Wolf, 2015, Sequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysis, PLoS One, 10, e0123533, 10.1371/journal.pone.0123533
Wong, 2000, Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice, Neuron, 27, 487, 10.1016/s0896-6273(00)00060-x
Worley, 2007, Homer proteins in Ca2+ signaling by excitable and non-excitable cells, Cell Calcium, 42, 363, 10.1016/j.ceca.2007.05.007
Wu, 2015, Lipocalin-2 enhances angiogenesis in rat brain endothelial cells via reactive oxygen species and iron-dependent mechanisms, J. Neurochem., 132, 622, 10.1111/jnc.13023
Wu, 2009, Estrogen masculinizes neural pathways and sex-specific behaviors, Cell, 139, 61, 10.1016/j.cell.2009.07.036
Wu, 2002, Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells, Proc. Natl. Acad. Sci. U S A, 99, 2392, 10.1073/pnas.042617699
Xia, 2001, Identification of a prostate-specific G-protein coupled receptor in prostate cancer, Oncogene, 20, 5903, 10.1038/sj.onc.1204803
Xing, 2014, Neuronal production of lipocalin-2 as a help-me signal for glial activation, Stroke, 45, 2085, 10.1161/STROKEAHA.114.005733
Xu, 2000, PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer, Cancer Res., 60, 6568
Yoder, 2014, The molecular evolutionary dynamics of the vomeronasal receptor (class 1) genes in primates: a gene family on the verge of a functional breakdown, Front. Neuroanat., 8, 153, 10.3389/fnana.2014.00153
Young, 2002, Different evolutionary processes shaped the mouse and human olfactory receptor gene families, Hum. Mol. Genet., 11, 535, 10.1093/hmg/11.5.535
Young, 2003, Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels, Genome Biol., 4, R71, 10.1186/gb-2003-4-11-r71
Yuan, 2001, Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species, Gene, 278, 41, 10.1016/s0378-1119(01)00709-0
Zerr, 2009, Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease, Brain, 132, 2659, 10.1093/brain/awp191
Zhang, 2012, G protein-coupled receptors participate in cytokinesis, Cytoskeleton (Hoboken), 69, 810, 10.1002/cm.21055
Zhang, 2007, Characterizing the expression of the human olfactory receptor gene family using a novel DNA microarray, Genome Biol., 8, R86, 10.1186/gb-2007-8-5-r86
Zhang, 2002, The olfactory receptor gene superfamily of the mouse, Nat. Neurosci., 5, 124, 10.1038/nn800
Zhang, 2004, High-throughput microarray detection of olfactory receptor gene expression in the mouse, Proc. Natl. Acad. Sci. U S A, 101, 14168, 10.1073/pnas.0405350101
Zhao, 2013, Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy, J. Alzheimers Dis., 34, 417, 10.3233/JAD-121894
